Publications by authors named "Paul Witting"

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Myeloperoxidase Luminol Reaction - A Novel Faecal Assay for Predicting Colonoscopy Findings in Patients with Ulcerative Colitis: A Pilot Cross-Sectional Clinical Study.
Viraj Kariyawasam, Taylor Davis, Mark Ghali, David Tejcek, Thomas R O'Neil, Paul K Witting

Adv Healthc Mater· August 2025

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The PAD4 inhibitor GSK484 diminishes neutrophil extracellular trap in the colon mucosa but fails to improve inflammatory biomarkers in experimental colitis.
Kangzhe Xie, Jordan Hunter, Aaron Lee, Gulfam Ahmad, Paul K Witting

Biosci Rep· May 2025

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Cyclic Nitroxide 4-Methoxy-Tempo May Decrease Serum Amyloid A-Mediated Renal Fibrosis and Reorganise Collagen Networks in Aortic Plaque.
Antony Gao, Kangzhe Xie, Sameesh Gupta, Gulfam Ahmad, Paul K Witting

Int J Mol Sci· July 2024

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Myeloperoxidase Gene Deletion Causes Drastic Microbiome Shifts in Mice and Does Not Mitigate Dextran Sodium Sulphate-Induced Colitis.
Patrick T San Gabriel, Thomas R O'Neil, Alice Au, Jian K Tan, Gabriela V Pinget, Paul K Witting

Int J Mol Sci· April 2024

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Effects of polyphenolic maqui () extract on the inhibition of NLRP3 inflammasome and activation of mast cells in a mouse model of Crohn's disease-like colitis.
Tamara Ortiz-Cerda, Federico Argüelles-Arias, Laura Macías-García, Victoria Vázquez-Román, Gladys Tapia, Paul K Witting

Front Immunol· January 2024

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Redox-Mediated Rewiring of Signalling Pathways: The Role of a Cellular Clock in Brain Health and Disease.
Filip Vujovic, Claire E Shepherd, Paul K Witting, Neil Hunter, Ramin M Farahani

Antioxidants (Basel)· October 2023

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Response to Low-density Granulocytes as Novel Biomarkers of Disease Activity in IBD.
Kangzhe Xie, Tamara Ortiz Cerda, Angie Schroder, Nicolette Shiung, Bruno Lemos Wimmer, Paul K Witting

Inflamm Bowel Dis· August 2023

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Myeloperoxidase in Health and Disease.
Tamara Ortiz-Cerda, Kangzhe Xie, Albaraa Mojadadi, Paul K Witting

Int J Mol Sci· April 2023

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Physiological Benefits of Novel Selenium Delivery via Nanoparticles.
Alice Au, Albaraa Mojadadi, Jia-Ying Shao, Gulfam Ahmad, Paul K Witting

Int J Mol Sci· March 2023

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Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice.
Yutang Wang, Dinh Tam Nguyen, Jack Anesi, Ahmed Alramahi, Paul K Witting

Int J Mol Sci· February 2023

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Dietary fatty acids and mortality risk from heart disease in US adults: an analysis based on NHANES.
Yutang Wang, Yan Fang, Paul K Witting, Fadi J Charchar, Christopher G Sobey

Sci Rep· January 2023

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Hypertension alters the function and expression profile of the peptide cotransporters PEPT1 and PEPT2 in the rodent renal proximal tubule.
Othman A Alghamdi, Nicola King, Nicholas M Andronicos, Graham L Jones, Belal Chami, Paul K Witting

Amino Acids· July 2022

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Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations.
Guang Yang, Tingting Qian, Hui Sun, Qun Xu, Xujuan Hou, Paul K Witting

J Hum Hypertens· June 2022

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Multiplex analysis of mass imaging data: Application to the pathology of experimental myocardial infarction.
Han Shi, Mary El Kazzi, Yuyang Liu, Antony Gao, Angie L Schroder, Paul K Witting

Acta Physiol (Oxf)· June 2022

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Evidence for Oxidative Pathways in the Pathogenesis of PD: Are Antioxidants Candidate Drugs to Ameliorate Disease Progression?
Alexander Leathem, Tamara Ortiz-Cerda, Joanne M Dennis, Paul K Witting

Int J Mol Sci· June 2022

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Neutrophil Extracellular Trap Density Increases With Increasing Histopathological Severity of Crohn's Disease.
Angie L Schroder, Belal Chami, Yuyang Liu, Chloe M Doyle, Mary El Kazzi, Paul K Witting

Inflamm Bowel Dis· March 2022

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The Cyclic Nitroxide TEMPOL Ameliorates Oxidative Stress but Not Inflammation in a Cell Model of Parkinson's Disease.
Alexander Leathem, Martin Simone, Joanne M Dennis, Paul K Witting

Antioxidants (Basel)· January 2022

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Pro-Inflammatory Serum Amyloid a Stimulates Renal Dysfunction and Enhances Atherosclerosis in Apo E-Deficient Mice.
Antony Gao, Sameesh Gupta, Han Shi, Yuyang Liu, Angie L Schroder, Paul K Witting

Int J Mol Sci· November 2021

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Immunomodulatory effects of intestinal mesenchymal cells in the context of inflammatory bowel disease.
Belal Chami, Paul K Witting

Acta Physiol (Oxf)· October 2021

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PTU, a novel ureido-fatty acid, inhibits MDA-MB-231 cell invasion and dissemination by modulating Wnt5a secretion and cytoskeletal signaling.
Yassir Al-Zubaidi, Yongjuan Chen, Md Khalilur Rahman, Bala Umashankar, Hassan Choucair, Paul K Witting

Biochem Pharmacol· October 2021

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Role for Selenium in Metabolic Homeostasis and Human Reproduction.
Albaraa Mojadadi, Alice Au, Wed Salah, Paul Witting, Gulfam Ahmad

Nutrients· September 2021

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Periodontitis induces endothelial dysfunction in mice.
Maria Parvaneh, Paul K Witting, Jaqueline Ku, Tala Moradi, Elif Eroglu

Sci Rep· July 2021

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Efficacy of the Piperidine Nitroxide 4-MethoxyTEMPO in Ameliorating Serum Amyloid A-Mediated Vascular Inflammation.
Nathan J Martin, Belal Chami, Abigail Vallejo, Albaraa A Mojadadi, Paul K Witting

Int J Mol Sci· April 2021

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Nitroxides Mitigate Neutrophil-Mediated Damage to the Myocardium after Experimental Myocardial Infarction in Rats.
Mary El Kazzi, Han Shi, Sally Vuong, Xiaosuo Wang, Belal Chami, Paul K Witting

Int J Mol Sci· October 2020

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The Synthetic Myeloperoxidase Inhibitor AZD3241 Ameliorates Dextran Sodium Sulfate Stimulated Experimental Colitis.
Gulfam Ahmad, Belal Chami, Yuyang Liu, Angie L Schroder, Patrick T San Gabriel, Paul K Witting

Front Pharmacol· September 2020

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