Publications by authors named "Pavithra Viswanath"

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Understanding and imaging PHGDH-driven intrinsic resistance to mutant IDH inhibition in gliomas.
Céline Taglang, Georgios Batsios, Anne Marie Gillespie, Joanna J Phillips, Jennie W Taylor, Pavithra Viswanath

bioRxiv· September 2025

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Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma.
Suresh Udutha, Céline Taglang, Georgios Batsios, Anne Marie Gillespie, Meryssa Tran, Pavithra Viswanath

Cell Rep· May 2025

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The 1p/19q co-deletion induces targetable and imageable vulnerabilities in glucose metabolism in oligodendrogliomas.
Suresh Udutha, Georgios Batsios, Céline Taglang, Anne Marie Gillespie, Pavithra Viswanath

bioRxiv· May 2025

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Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in H3K27M-mutant gliomas.
Georgios Batsios, Céline Taglang, Suresh Udutha, Anne Marie Gillespie, Simon P Robinson, Pavithra Viswanath

bioRxiv· January 2025

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GABA production induced by imipridones is a targetable and imageable metabolic alteration in diffuse midline gliomas.
Georgios Batsios, Suresh Udutha, Céline Taglang, Anne Marie Gillespie, Benison Lau, Pavithra Viswanath

bioRxiv· June 2024

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Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas.
Suresh Udutha, Céline Taglang, Georgios Batsios, Anne Marie Gillespie, Meryssa Tran, Pavithra Viswanath

bioRxiv· November 2023

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Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-C]-gluconolactone.
Georgios Batsios, Celine Taglang, Anne Marie Gillespie, Pavithra Viswanath

Neurooncol Adv· July 2023

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Hyperpolarized δ-[1- C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.
Noriaki Minami, Donghyun Hong, Celine Taglang, Georgios Batsios, Anne Marie Gillespie, Pavithra Viswanath

Sci Rep· March 2023

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Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.
Noriaki Minami, Donghyun Hong, Nicholas Stevers, Carter J Barger, Marina Radoul, Pavithra Viswanath

Neuro Oncol· November 2022

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A C/P surface coil to visualize metabolism and energetics in the rodent brain at 3 Tesla.
Manushka V Vaidya, Bei Zhang, DongHyun Hong, Ryan Brown, Georgios Batsios, Pavithra Viswanath

J Magn Reson· October 2022

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Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer.
Georgios Batsios, Céline Taglang, Meryssa Tran, Nicholas Stevers, Carter Barger, Pavithra Viswanath

Clin Cancer Res· August 2022

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Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.
Céline Taglang, Georgios Batsios, Joydeep Mukherjee, Meryssa Tran, Anne Marie Gillespie, Pavithra Viswanath

Neuro Oncol· July 2022

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Acquisition and quantification pipeline for in vivo hyperpolarized C MR spectroscopy.
Donghyun Hong, Georgios Batsios, Pavithra Viswanath, Anne Marie Gillespie, Manushka Vaidya

Magn Reson Med· April 2022

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Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.
Pavithra Viswanath, Georgios Batsios, Vinay Ayyappan, Céline Taglang, Anne Marie Gillespie

Neuro Oncol· September 2021

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Deuterium Metabolic Imaging-Rediscovery of a Spectroscopic Tool.
Ilona Polvoy, Hecong Qin, Robert R Flavell, Jeremy Gordon, Pavithra Viswanath

Metabolites· August 2021

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Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies.
Ning Zhao, Yangjie Huang, Yung-Hua Wang, Ryan K Muir, Ying-Chu Chen, Pavithra Viswanath

J Nucl Med· July 2021

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MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.
Abigail R Molloy, Chloé Najac, Pavithra Viswanath, Aliya Lakhani, Elavarasan Subramani

Theranostics· May 2021

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Imaging 6-Phosphogluconolactonase Activity in Brain Tumors Using Hyperpolarized δ-[1-C]gluconolactone.
Georgios Batsios, Céline Taglang, Peng Cao, Anne Marie Gillespie, Chloé Najac, Pavithra Viswanath

Front Oncol· April 2021

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Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.
Marina Radoul, Donghyun Hong, Anne Marie Gillespie, Chloé Najac, Pavithra Viswanath

Metabolites· February 2021

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Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
Pavithra Viswanath, Georgios Batsios, Joydeep Mukherjee, Anne Marie Gillespie, Peder E Z Larson

Nat Commun· January 2021

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Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment.
Elavarasan Subramani, Marina Radoul, Chloe Najac, Georgios Batsios, Abigail R Molloy, Pavithra Viswanath

Cancer Res· November 2020

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In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-C]glycine.
Georgios Batsios, Chloé Najac, Peng Cao, Pavithra Viswanath, Elavarasan Subramani

Sci Rep· April 2020

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PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.
Georgios Batsios, Pavithra Viswanath, Elavarasan Subramani, Chloe Najac, Anne Marie Gillespie

Sci Rep· July 2019

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In vivo investigation of hyperpolarized [1,3-C]acetoacetate as a metabolic probe in normal brain and in glioma.
Chloé Najac, Marina Radoul, Lydia M Le Page, Georgios Batsios, Elavarasan Subramani, Pavithra Viswanath

Sci Rep· March 2019

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HDAC inhibition in glioblastoma monitored by hyperpolarized C MRSI.
Marina Radoul, Chloé Najac, Pavithra Viswanath, Joydeep Mukherjee, Mark Kelly

NMR Biomed· February 2019

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