Publications by authors named "Paz Polak"

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Passenger mutations link cellular origin and transcriptional identity in human lung adenocarcinomas.
Sukanya Panja, Padmaja Mantri, Kofi Ennu Johnson, Juan Sebastian Andrade-Martinez, Soo-Ryum Yang, Paz Polak

Nat Genet· December 2025

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APC-related multiple salivary gland lesions: spatial transcriptomic analysis reveals progressive WNT activation.
Fiona Chan-Pak-Choon, Catherine Beaumont, José Camacho Valenzuela, Josianne Leblanc, Sonja Dahlum, Paz Polak

J Pathol· November 2025

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Learning the cellular origins across cancers using single-cell chromatin landscapes.
Mohamad D Bairakdar, Wooseung Lee, Bruno Giotti, Akhil Kumar, Paula Stancl, Paz Polak

Nat Commun· September 2025

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Probing the relevance of BRCA1 and BRCA2 germline pathogenic variants beyond breast and ovarian cancer.
William D Foulkes, Paz Polak

J Natl Cancer Inst· December 2024

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Whole-genome Mutational Analysis for Tumor-informed Detection of Circulating Tumor DNA in Patients with Urothelial Carcinoma.
Iver Nordentoft, Sia Viborg Lindskrog, Karin Birkenkamp-Demtröder, Santiago Gonzalez, Maja Kuzman, Paz Polak

Eur Urol· October 2024

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Host Nuclear Genome Copy Number Variations Identify High-Risk Anal Precancers in People Living With HIV.
Tinaye Mutetwa, Yuxin Liu, Richard Silvera, Michelle Evans, Michael Yurich, Paz Polak

J Acquir Immune Defic Syndr· June 2024

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Exercise-Induced Cell-Free DNA Correlates with Energy Expenditure in Multiple Exercise Protocols.
Christopher D Nogiec, Rosa Karlic, Eddie Taborda, Sonia Dunkelbarger, Ori Fridlich, Paz Polak

Med Sci Sports Exerc· May 2024

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Whole-exome sequencing of Nigerian benign prostatic hyperplasia reveals increased alterations in apoptotic pathways.
Jason A White, Ernest T Kaninjing, Kayode A Adeniji, Paul Jibrin, John O Obafunwa, Paz Polak

Prostate· April 2024

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Actionable Genotypes and Life Span in Iceland.
William D Foulkes, Paz Polak

N Engl J Med· March 2024

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PD-1 and PD-L1 Blockade plus Chemotherapy in Endometrial Cancer.
Paz Polak, Lili Fu, William D Foulkes

N Engl J Med· August 2023

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Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer.
William D Foulkes, Paz Polak, Rosa Karlić

N Engl J Med· July 2023

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Elevated cfDNA after exercise is derived primarily from mature polymorphonuclear neutrophils, with a minor contribution of cardiomyocytes.
Ori Fridlich, Ayelet Peretz, Ilana Fox-Fisher, Sheina Pyanzin, Ziv Dadon, Paz Polak

Cell Rep Med· June 2023

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Long-term tumour dormancy in a heterozygote.
Setor Amuzu, Lili Fu, Nadine Demko, Barbara Rivera, Celine Domecq, Paz Polak

J Med Genet· January 2023

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Author Correction: A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA.
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A Eden Cruikshank, Katheryn Santos, Paz Polak

Nat Commun· January 2023

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A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA.
Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A Eden Cruikshank, Katheryn Santos, Paz Polak

Nat Commun· December 2022

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Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen

Nat Commun· December 2022

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COOBoostR: An Extreme Gradient Boosting-Based Tool for Robust Tissue or Cell-of-Origin Prediction of Tumors.
Sungmin Yang, Kyungsik Ha, Woojeung Song, Masashi Fujita, Kirsten Kübler, Paz Polak

Life (Basel)· December 2022

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Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
Jason A White, Ernest T Kaninjing, Kayode A Adeniji, Paul Jibrin, John O Obafunwa, Paz Polak

Cancer Res Commun· September 2022

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Diverse mutational landscapes in human lymphocytes.
Heather E Machado, Emily Mitchell, Nina F Øbro, Kirsten Kübler, Megan Davies, Paz Polak

Nature· August 2022

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Characterization of genetic predisposition to molecular subtypes of breast cancer in Brazilian patients.
Daniele Paixão, Giovana Tardin Torrezan, Karina Miranda Santiago, Maria Nirvana Formiga, Samuel Terkper Ahuno, Paz Polak

Front Oncol· August 2022

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Machine-learning of complex evolutionary signals improves classification of SNVs.
Sapir Labes, Doron Stupp, Naama Wagner, Idit Bloch, Michal Lotem, Paz Polak

NAR Genom Bioinform· June 2022

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The Great Majority of Homologous Recombination Repair-Deficient Tumors Are Accounted for by Established Causes.
Paula Štancl, Nancy Hamel, Keith M Sigel, William D Foulkes, Rosa Karlić, Paz Polak

Front Genet· June 2022

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Cell-free DNA profiling informs all major complications of hematopoietic cell transplantation.
Alexandre Pellan Cheng, Matthew Pellan Cheng, Conor James Loy, Joan Sesing Lenz, Kaiwen Chen, Paz Polak

Proc Natl Acad Sci U S A· January 2022

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Companion Tumor Sequencing to Assess the Clinical Significance of Germline Sequencing in Children With Cancer.
Tinaye Mutetwa, Catherine Goudie, William D Foulkes, Paz Polak

JAMA Netw Open· November 2021

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Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa.
Samuel Terkper Ahuno, Anna-Lisa Doebley, Thomas U Ahearn, Joel Yarney, Nicholas Titiloye, Paz Polak

NPJ Precis Oncol· September 2021

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