Publications by authors named "Pedro Bule"

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Tripartite binding mode of cohesin-dockerin complexes from Ruminococcus flavefaciens involving naturally truncated dockerins.
Marlene Duarte, Ana Luísa Carvalho, Magda C Ferreira, Beatriz Caires, Maria João Romão, Pedro Bule

J Biol Chem· July 2025

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A new treatment for canine B-cell lymphoma based on a recombinant single-domain antibody immunotoxin derived from exotoxin A.
Ana S André, Joana N R Dias, Isa Moutinho, Joana Loureiro, Ana Leonardo, Pedro Bule

Front Vet Sci· April 2025

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Family GH157 enzyme exhibits broad linkage tolerance and a dual endo/exo-β-glucanase activity on β-glucans.
Catarina Caseiro, Nicholas G S McGregor, Victor Diogo Alves, Ana Luísa Carvalho, Maria João Romão, Pedro Bule

Int J Biol Macromol· December 2024

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New insights into the immunomodulatory potential of sialic acid on monocyte-derived dendritic cells.
Zélia Silva, João Amorim Rabaça, Vanessa Luz, Rita Adubeiro Lourenço, Mariolina Salio, Pedro Bule

Cancer Immunol Immunother· November 2024

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Rabbit derived VL single-domains as promising scaffolds to generate antibody-drug conjugates.
Ana S André, Joana N R Dias, Sandra Aguiar, Sara Nogueira, Pedro Bule

Sci Rep· March 2023

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Structure-function studies can improve binding affinity of cohesin-dockerin interactions for multi-protein assemblies.
Marlene Duarte, Victor D Alves, Márcia Correia, Catarina Caseiro, Luís M A Ferreira, Pedro Bule

Int J Biol Macromol· January 2023

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In Silico Characterization of African Swine Fever Virus Nucleoprotein p10 Interaction with DNA.
Claudia Istrate, Jéssica Marques, Pedro Bule, Sílvia Correia, Frederico Aires-da-Silva

Viruses· October 2022

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Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.
Casper de Boer, Zachary Armstrong, Vincent A J Lit, Uri Barash, Gijs Ruijgrok, Pedro Bule

Proc Natl Acad Sci U S A· August 2022

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Recalcitrant cell wall of seaweed is degraded by a single ulvan lyase from family 25 of polysaccharide lyases.
Mónica M Costa, Luís B Pio, Pedro Bule, Vânia A Cardoso, Marlene Duarte

Anim Nutr· June 2022

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From Cancer Therapy to Winemaking: The Molecular Structure and Applications of β-Glucans and β-1, 3-Glucanases.
Catarina Caseiro, Joana Nunes Ribeiro Dias, Carlos Mendes Godinho de Andrade Fontes, Pedro Bule

Int J Mol Sci· March 2022

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Characterization of the canine CD20 as a therapeutic target for comparative passive immunotherapy.
Joana N R Dias, André Almeida, Ana S André, Sandra I Aguiar, Pedro Bule

Sci Rep· February 2022

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Chemokine-Directed Tumor Microenvironment Modulation in Cancer Immunotherapy.
Pedro Bule, Sandra Isabel Aguiar, Frederico Aires-Da-Silva, Joana Nunes Ribeiro Dias

Int J Mol Sci· September 2021

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A dual cohesin-dockerin complex binding mode in Bacteroides cellulosolvens contributes to the size and complexity of its cellulosome.
Marlene Duarte, Aldino Viegas, Victor D Alves, José A M Prates, Luís M A Ferreira, Pedro Bule

J Biol Chem· August 2021

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An individual alginate lyase is effective in the disruption of Laminaria digitata recalcitrant cell wall.
Mónica Costa, Luís Pio, Pedro Bule, Vânia Cardoso, Cristina M Alfaia

Sci Rep· May 2021

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Cellulosomes: Highly Efficient Cellulolytic Complexes.
Victor D Alves, Carlos M G A Fontes, Pedro Bule

Subcell Biochem· February 2021

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Molecular basis for the preferential recognition of β1,3-1,4-glucans by the family 11 carbohydrate-binding module from Clostridium thermocellum.
Diana O Ribeiro, Aldino Viegas, Virgínia M R Pires, João Medeiros-Silva, Pedro Bule

FEBS J· July 2020

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Molecular Cloning, Expression and Biochemical Characterization of a Family 5 Glycoside Hydrolase First Endo-Mannanase (RfGH5_7) from Ruminococcus flavefaciens FD-1 v3.
Dishant Goyal, Krishan Kumar, Maria S J Centeno, Abhijeet Thakur, Virgínia M R Pires, Pedro Bule

Mol Biotechnol· November 2019

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Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action.
Pedro Bule, Léa Chuzel, Elena Blagova, Liang Wu, Melissa A Gray

Nat Commun· October 2019

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Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction.
Pedro Bule, Virgínia M R Pires, Victor D Alves, Ana Luísa Carvalho, José A M Prates

Sci Rep· May 2018

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Cellulosome assembly: paradigms are meant to be broken!
Pedro Bule, Virgínia Mr Pires, Carlos Mga Fontes, Victor D Alves

Curr Opin Struct Biol· April 2018

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Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Andriy Kryshtafovych, Reinhard Albrecht, Arnaud Baslé, Pedro Bule, Alessandro T Caputo

Proteins· March 2018

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Structure-function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes.
Pedro Bule, Kate Cameron, José A M Prates, Luís M A Ferreira, Steven P Smith

J Biol Chem· March 2018

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Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes.
Pedro Bule, Victor D Alves, Vered Israeli-Ruimy, Ana L Carvalho, Luís M A Ferreira

Sci Rep· April 2017

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Stability and Ligand Promiscuity of Type A Carbohydrate-binding Modules Are Illustrated by the Structure of CBM64C.
Virgínia M R Pires, Pedro M M Pereira, Joana L A Brás, Márcia Correia, Vânia Cardoso, Pedro Bule

J Biol Chem· March 2017

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Complexity of the Ruminococcus flavefaciens FD-1 cellulosome reflects an expansion of family-related protein-protein interactions.
Vered Israeli-Ruimy, Pedro Bule, Sadanari Jindou, Bareket Dassa, Sarah Moraïs

Sci Rep· February 2017

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