Publications by authors named "Pedro Pinheiro"

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Exploring the Impact of 3--Methylquercetin on Wnt/β-Catenin Pathway Activity and Its Potential in Neural Processes.
Kamila Leichtweis, Danilo Predes, Marielly C Mangelli, Hugo Mauricio, Barbara S M de Jesus, Pedro S M Pinheiro

Pharmaceuticals (Basel)· November 2025

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Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease.
Pedro de Sena M Pinheiro, Francesca de Chirico, Manuela Loi, Stefania Trazzi, Elisabetta Ciani

Eur J Med Chem· October 2025

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Histone Deacetylases in Neurodegenerative Diseases and Their Potential Role as Therapeutic Targets: Shedding Light on Astrocytes.
Pedro de Sena Murteira Pinheiro, Luan Pereira Diniz, Lucas S Franco, Michele Siqueira, Flávia Carvalho Alcantara Gomes

Pharmaceuticals (Basel)· September 2025

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HDACs in the Brain: From Chromatin Remodeling to Neurodegenerative Disease.
Luan Pereira Diniz, Pedro de Sena Murteira Pinheiro, Lucas S Franco, Flávia Carvalho Alcantara Gomes

Cells· August 2025

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A smart energy management system for surface unmanned vehicles for border surveillance missions.
João F P Fernandes, Mário Assunção, Daniel Serrano, Pedro Afonso, Pedro Pinheiro

Sci Rep· July 2025

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Drug Repurposing by Virtual Screening: Identification of New Already Approved ROCK Inhibitors as Promising Drugs to Target Neurodegeneration.
Lucas Silva Franco, Daniel Alencar Rodrigues, Gabriela Joras Baumart, Bárbara da Silva Mascarenhas de Jesus, Flávia Carvalho Alcantara Gomes, Pedro de Sena Murteira Pinheiro

ACS Omega· July 2025

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Deep learning models for improving Parkinson's disease management regarding disease stage, motor disability and quality of life.
Helena R Gonçalves, Pedro Pinheiro, Cristiana Pinheiro, Luís Martins, Ana Margarida Rodrigues

Comput Biol Med· May 2025

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Exploring the Conformational Effects of - and -Methylation of -Acylhydrazones.
Lucas Silva Franco, Marina Amaral Alves, Carlos Mauricio R Sant'Anna, Isadora Tairinne de Sena Bastos, Regina Cely Rodrigues Barroso, Pedro de Sena M Pinheiro

ACS Omega· May 2025

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Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups.
Gustavo Salgado Pires, Heber Victor Tolomeu, Daniel Alencar Rodrigues, Lídia Moreira Lima, Carlos Alberto Manssour Fraga, Pedro de Sena Murteira Pinheiro

Pharmaceuticals (Basel)· April 2025

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The Impact of the COVID-19 Pandemic on Cardiovascular Diseases Hospitalizations in Brazil.
Antonio Fagundes, Camila de Castro Silva, Fernanda de Sousa Rodrigues, Maria Carolina Fonseca Loureiro Caldeira de Freitas, Luiz Guilherme Passaglia, Pedro C Pinheiro

JACC Adv· February 2025

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Regioselective Nucleophilic Aromatic Substitution: Theoretical and Experimental Insights into 4-Aminoquinazoline Synthesis as a Privileged Structure in Medicinal Chemistry.
Maria Letícia de Castro Barbosa, Pedro de Sena Murteira Pinheiro, Raissa Alves da Conceição, José Ricardo Pires, Lucas Silva Franco

Molecules· December 2024

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The Elusive Biological Activity of Scorpionates: A Useful Scaffold for Cancer Therapy?
Artem Petrosian, Pedro F Pinheiro, Ana P C Ribeiro, Luísa M D R S Martins, Gonçalo C Justino

Molecules· November 2024

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Modulating the phototoxicity and selectivity of a porphyrazine towards epidermal tumor cells by coordination with metal ions.
Pedro A Pinheiro, Gabriel F M Pereira, Leandro O Cunha, Julia P S C Leal, Meiry E Alvarenga

Photochem Photobiol Sci· September 2024

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Remapping the Chemical Space and the Pharmacological Space of Drugs: What Can We Expect from the Road Ahead?
Lucas Silva Franco, Bárbara da Silva Mascarenhas de Jesus, Pedro de Sena Murteira Pinheiro, Carlos Alberto Manssour Fraga

Pharmaceuticals (Basel)· June 2024

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First Case Report of Bilateral Parotid Lymphoepithelial Carcinoma.
Willer Everton Feitosa Meneses, Pedro Henrique Cunha Lima DO Rego, Valdenor Neves Feitosa Junior, Herbert Tavares Palmeira, Douglas Henning Pinheiro Aragao, Pedro Miguel Azevedo Pinheiro

Cancer Diagn Progn· May 2024

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Milk and Fresh Cheese Quality of Crossbred Cows Supplemented with Phytogenic Additives and Managed under Thermal Stress.
Abner Alves Mesquita, Poliana Carneiro Martins, Patrick Bezerra Fernandes, Leonardo Amorim de Oliveira, Paulo Victor Toledo Leão, Pedro Paulo Alves Pinheiro

Animals (Basel)· November 2023

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The Magic Methyl and Its Tricks in Drug Discovery and Development.
Pedro de Sena Murteira Pinheiro, Lucas Silva Franco, Carlos Alberto Manssour Fraga

Pharmaceuticals (Basel)· August 2023

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Jejunal Gastrointestinal Stromal Tumor: A Strange Cause of Massive Gastrointestinal Bleeding.
Daniela Martins, Pedro Costa, Gonçalo Guidi, Pedro Pinheiro, João A Pinto-de-Sousa

Cureus· August 2023

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Exploring the Mechanisms behind the Anti-Tumoral Effects of Model C-Scorpionate Complexes.
Pedro M G Silva, Pedro F Pinheiro, Sérgio P Camões, Ana P C Ribeiro, Luísa M D R S Martins

Molecules· July 2023

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Depression Screening in a population-based study: Brazilian National Health Survey 2019.
Ana Paula Souto Melo, Cecília Silva Costa Bonadiman, Fabiana Martins de Andrade, Pedro Cisalpino Pinheiro, Deborah Carvalho Malta

Cien Saude Colet· April 2023

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Premature mortality due to noncommunicable diseases in Brazilian capitals: redistribution of garbage causes and evolution by social deprivation strata.
Deborah Carvalho Malta, Renato Azeredo Teixeira, Laís Santos de Magalhães Cardoso, Juliana Bottoni de Souza, Regina Tomie Ivata Bernal, Pedro Cisalpino Pinheiro

Rev Bras Epidemiol· April 2023

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Protocol to study in vitro drug metabolism and identify montelukast metabolites from purified enzymes and primary cell cultures by mass spectrometry.
Cátia F Marques, Pedro F Pinheiro, Gonçalo C Justino

STAR Protoc· March 2023

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Hybrid model for early identification post-Covid-19 sequelae.
Evandro Carvalho de Andrade, Luana Ibiapina C C Pinheiro, Plácido Rogério Pinheiro, Luciano Comin Nunes, Mirian Calíope Dantas Pinheiro, Pedro Gabriel C D Pinheiro

J Ambient Intell Humaniz Comput· February 2023

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Optimized protocol for obtaining and characterizing primary neuron-enriched cultures from embryonic chicken brains.
Cátia F Marques, Pedro F Pinheiro, Gonçalo C Justino

STAR Protoc· December 2022

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Methyl Effect on the Metabolism, Chemical Stability, and Permeability Profile of Bioactive -Sulfonylhydrazones.
Jéssica de Siqueira Guedes, Teiliane Rodrigues Carneiro, Pedro de Sena Murteira Pinheiro, Carlos Alberto Manssour Fraga, Carlos Mauricio R Sant Anna

ACS Omega· November 2022

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