Publications by authors named "Pengda Liu"

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cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S Umbaugh, Pengda Liu

Adv Sci (Weinh)· December 2025

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Phosphorylation of UDP-glucose dehydrogenase increases glycosaminoglycan biosynthesis and promotes tumor cell motility, spheroid growth, and therapeutic resistance.
Asher R Utz, Linlin Ma, Dalton Hilovsky, Brenna M Zimmer, Emily Allego, Pengda Liu, Xiaojing Liu

Matrix Biol· December 2025

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Molecular glue degrader function of SPOP inhibitors enhances STING-dependent immunotherapy efficacy in melanoma models.
Zhichuan Zhu, Xin Zhou, Max Xu, Jianfeng Chen, Kevin C Robertson, Pengda Liu

J Clin Invest· December 2025

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Stable Cas9 expression regulates cell growth by facilitating mTORC2 activation.
Le Yu, Yi Jin, Jianfeng Chen, Zhichuan Zhu, Siyuan Su, Pengda Liu

Nucleic Acids Res· September 2025

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OTU deubiquitinases in disease: roles and targeting.
Yu Deng, Pengda Liu

Trends Mol Med· June 2025

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The Rab18/Ras/ERK/FosB/MMP3 Signaling Pathway Mediates Cell Migration Regulation by 2'3'-cGAMP.
Yu Deng, Runjie Yuan, Pengda Liu

Int J Mol Sci· June 2025

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(GGAA)-Based TF-PROTACs Enable Targeted Degradation of ETV6 to Inhibit Ewing Sarcoma Growth.
Zhichuan Zhu, He Chen, Xing Qiu, H Umit Kaniskan, Ling Xie, Pengda Liu

J Am Chem Soc· April 2025

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Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells.
Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Pengda Liu

Nat Commun· February 2025

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cGAS/STING signalling pathway in senescence and oncogenesis.
Le Yu, Pengda Liu

Semin Cancer Biol· November 2024

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Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency.
Jianfeng Chen, Siyuan Su, Adrian Pickar-Oliver, Anna M Chiarella, Quentin Hahn, Pengda Liu

Nucleic Acids Res· October 2024

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2'3'-cGAMP interactome identifies 2'3'-cGAMP/Rab18/FosB signaling in cell migration control independent of innate immunity.
Yu Deng, Quentin Hahn, Le Yu, Zhichuan Zhu, Joshua A Boyer, Pengda Liu

Sci Adv· October 2024

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Dynamic Event-Triggered Safe Control for Nonlinear Game Systems With Asymmetric Input Saturation.
Pengda Liu, Huiyan Zhang, Zhongyang Ming, Shuoyu Wang, Ramesh K Agarwal

IEEE Trans Cybern· September 2024

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Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells.
Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Pengda Liu

bioRxiv· September 2024

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Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in Ewing sarcoma.
Le Yu, Yu Deng, Xiaodong Wang, Charlene Santos, Ian J Davis, Pengda Liu

Nat Commun· June 2024

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Introducing a Pyrazinoquinoxaline Derivative into a Metal-Organic Framework: Achieving Fluorescence-Enhanced Detection for Cs and Enhancing Photocatalytic Activity.
Ao-Gang Liu, Xiao-Yu Meng, Yuan Chen, Zi-Tong Chen, Peng-da Liu

ACS Appl Mater Interfaces· January 2024

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MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Min-Guk Cho, Rashmi J Kumar, Chien-Chu Lin, Joshua A Boyer, Jamshaid A Shahir, Pengda Liu

Nature· January 2024

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AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms.
Johnny Castillo Cabrera, Hong Dang, Adam Graves, Zhigang Zhang, Jose Torres-Castillo, Pengda Liu

Cell Chem Biol· December 2023

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Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function.
Jianfeng Chen, Xinyi Zhang, Xianming Tan, Pengda Liu

J Exp Med· October 2023

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SETDB1 Triple Tudor Domain Ligand, (,)-59, Promotes Methylation of Akt1 in Cells.
Mélanie Uguen, Yu Deng, Fengling Li, Devan J Shell, Jacqueline L Norris-Drouin, Pengda Liu

ACS Chem Biol· August 2023

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Development of VHL-recruiting STING PROTACs that suppress innate immunity.
Zhichuan Zhu, Rebecca L Johnson, Zhigang Zhang, Laura E Herring, Guochun Jiang, Pengda Liu

Cell Mol Life Sci· May 2023

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SETDB1 Triple Tudor Domain Ligand, ( )-59, Promotes Methylation of Akt1 in Cells.
Mélanie Uguen, Yu Deng, Fengling Li, Devan J Shell, Jacqueline L Norris-Drouin, Pengda Liu

bioRxiv· May 2023

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STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
Zhichuan Zhu, Xin Zhou, Hongwei Du, Erica W Cloer, Jiaming Zhang, Liu Mei, Pengda Liu

Adv Sci (Weinh)· January 2023

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Regulation of EWSR1-FLI1 Function by Post-Transcriptional and Post-Translational Modifications.
Le Yu, Ian J Davis, Pengda Liu

Cancers (Basel)· January 2023

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AtomNet-Aided OTUD7B Inhibitor Discovery and Validation.
Jianfeng Chen, Derek L Bolhuis, Christian Laggner, Deyu Kong, Le Yu, Pengda Liu

Cancers (Basel)· January 2023

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Application of Copper(II)-Organic Frameworks Bearing Dilophine Derivatives in Photocatalysis and Guest Separation.
Yuan Chen, Ao-Gang Liu, Peng-da Liu, Zhen-Yi Zhang, Fan Yu

Inorg Chem· October 2022

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