Publications by authors named "Pengrong Yan"

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Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2.
Fan Sun, Pengrong Yan, Yadong Xiao, Hongqiao Zhang, Steven D Shapiro

Elife· December 2024

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Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation.
Tanaya Roychowdhury, Seth W McNutt, Chiranjeevi Pasala, Hieu T Nguyen, Daniel T Thornton, Nan Yang, Pengrong Yan

Nat Commun· October 2024

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Neutrophil extracellular trap related risk score exhibits crucial prognostic value in skin cutaneous melanoma, associating with distinct immune characteristics.
Haiyang Zhang, Xiaoqing Bi, Pengrong Yan, Congcong Wang

Skin Res Technol· August 2024

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Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation.
Seth W McNutt, Tanaya Roychowdhury, Chiranjeevi Pasala, Hieu T Nguyen, Daniel T Thornton, Nan Yang, Pengrong Yan

Res Sq· April 2024

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Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2.
Fan Sun, Pengrong Yan, Yadong Xiao, Hongqiao Zhang, Steven D Shapiro

bioRxiv· January 2024

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How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view.
Matteo Castelli, Pengrong Yan, Anna Rodina, Chander S Digwal, Palak Panchal

Structure· August 2023

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Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.
Anna Rodina, Chao Xu, Chander S Digwal, Suhasini Joshi, Yogita Patel, Pengrong Yan, Chenghua Yang, Yanlong Kang, Meng-Fu Bryan Tsou

Nat Commun· June 2023

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Disease-specific interactome alterations via epichaperomics: the case for Alzheimer's disease.
Stephen D Ginsberg, Thomas A Neubert, Sahil Sharma, Chander S Digwal, Pengrong Yan

FEBS J· April 2022

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Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.
Suhasini Joshi, Erica DaGama Gomes, Tai Wang, Adriana Corben, Tony Taldone, Pengrong Yan, Wanyan Wang

Commun Biol· November 2021

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Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system.
Alexander Bolaender, Danuta Zatorska, Huazhong He, Suhasini Joshi, Sahil Sharma, Pengrong Yan

Nat Commun· August 2021

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Chaperome Networks - Redundancy and Implications for Cancer Treatment.
Pengrong Yan, Tai Wang, Monica L Guzman, Radu I Peter, Gabriela Chiosis

Adv Exp Med Biol· June 2020

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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone.
Pengrong Yan, Hardik J Patel, Sahil Sharma, Adriana Corben, Tai Wang, Chenghua Yang

Cell Rep· June 2020

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A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond.
Tony Taldone, Tai Wang, Anna Rodina, Naga Vara Kishore Pillarsetty, Chander S Digwal, Pengrong Yan

Cold Spring Harb Perspect Biol· April 2020

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Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs.
Dany Pechalrieu, Fanny Assemat, Ludovic Halby, Marlene Marcellin, Pengrong Yan

ACS Chem Biol· April 2020

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The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
Maria Carmen Inda, Suhasini Joshi, Tai Wang, Alexander Bolaender, Srinivasa Gandu, Pengrong Yan

Nat Commun· January 2020

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Paradigms for Precision Medicine in Epichaperome Cancer Therapy.
Nagavarakishore Pillarsetty, Komal Jhaveri, Tony Taldone, Eloisi Caldas-Lopes, Blesida Punzalan, Pengrong Yan

Cancer Cell· November 2019

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Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance.
Fan Sun, Liwen Li, Pengrong Yan, Jingjiao Zhou, Steven D Shapiro

Nat Commun· November 2019

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Reply to 'H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines'.
Mariano J Alvarez, Pengrong Yan, Mary L Alpaugh, Michaela Bowden, Ewa Sicinska

Nat Genet· October 2019

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The epichaperome is an integrated chaperome network that facilitates tumour survival.
Anna Rodina, Tai Wang, Pengrong Yan, Erica DaGama Gomes, Mark P S Dunphy, Chenghua Yang

Nature· October 2016

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Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94.
Hardik J Patel, Pallav D Patel, Stefan O Ochiana, Pengrong Yan, Weilin Sun

J Med Chem· May 2015

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Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.
Anna Rodina, Tony Taldone, Yanlong Kang, Pallav D Patel, John Koren, Pengrong Yan, Chenghua Yang

ACS Chem Biol· August 2014

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Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.
Anna Rodina, Pallav D Patel, Yanlong Kang, Yogita Patel, Imad Baaklini, Pengrong Yan, Chenghua Yang

Chem Biol· December 2013

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Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
Pallav D Patel, Pengrong Yan, Paul M Seidler, Hardik J Patel, Weilin Sun, Chenghua Yang

Nat Chem Biol· November 2013

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The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis.
Jing Fu, Zhaoxia Qu, Pengrong Yan, Chie Ishikawa, Rami I Aqeilan

Blood· February 2011

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Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer.
Zhaoxia Qu, Jing Fu, Pengrong Yan, Jing Hu, Shi-Yuan Cheng

J Biol Chem· April 2010

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