Publications by authors named "Penny Groves"

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Transcriptomic Plasticity of Human Alveolar Macrophages Revealed by Single-Cell RNA Sequencing Following Drug Exposure: Implications for Therapeutic Development.
Penny L Groves, Levi Hockey, Brendan J O'Sullivan, Lai-Ying Zhang, Zherui Xiong

Int J Mol Sci· May 2025

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A Methodological Approach to Identify Natural Compounds with Antifibrotic Activity and the Potential to Treat Pulmonary Fibrosis Using Single-Cell Sequencing and Primary Human Lung Macrophages.
Simon H Apte, Penny L Groves, Maxine E Tan, Viviana P Lutzky, Tharushi de Silva

Int J Mol Sci· October 2023

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Proteomic identification of the contents of small extracellular vesicles from in vivo Plasmodium yoelii infection.
Karina P De Sousa, Jeremy Potriquet, Jason Mulvenna, Javier Sotillo, Penny L Groves

Int J Parasitol· January 2022

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Identification of the Glycan Binding Profile of Human and Rodent Sporozoites.
Jessica Poole, Lauren E Hartley-Tassell, Christopher J Day, Danielle I Stanisic, Penny L Groves

ACS Infect Dis· August 2021

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Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8 T Cell Responses but Differ in Capacity to Induce CD4 T Cell Responses and Antibody Responses.
David J Pattinson, Simon H Apte, Nani Wibowo, Tania Rivera-Hernandez, Penny L Groves

Front Immunol· May 2021

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A population of CD4CD38 T cells correlates with disease severity in patients with acute malaria.
Simon H Apte, Gabriela Minigo, Penny L Groves, Jessie C Spargo, Magdalena Plebanski

Clin Transl Immunology· November 2020

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Chimeric Murine Polyomavirus Virus-Like Particles Induce Antigen-Specific CD8 T Cell and Antibody Responses.
David J Pattinson, Simon H Apte, Nani Wibowo, Yap P Chuan, Tania Rivera-Hernandez, Penny L Groves

Front Cell Infect Microbiol· February 2020

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A Balanced Proinflammatory and Regulatory Cytokine Signature in Young African Children Is Associated With Lower Risk of Clinical Malaria.
Carlota Dobaño, Augusto J Nhabomba, Maria N Manaca, Tamara Berthoud, Ruth Aguilar, Penny L Groves

Clin Infect Dis· August 2019

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Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties.
Phurpa Wangchuk, Simon H Apte, Michael J Smout, Penny L Groves, Alex Loukas

Int J Mol Sci· November 2018

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Influence of Physicochemical Properties of Lipopeptide Adjuvants on the Immune Response: A Rationale for Engineering a Potent Vaccine.
Sharareh Eskandari, David J Pattinson, Rachel J Stephenson, Penny L Groves, Simon H Apte

Chemistry· July 2018

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High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection.
Carlota Dobaño, Tamara Berthoud, Maria Nelia Manaca, Augusto Nhabomba, Caterina Guinovart, Penny Groves

Malar J· May 2018

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Dichotomous miR expression and immune responses following primary blood-stage malaria.
Julie G Burel, Simon H Apte, Penny L Groves, Michelle J Boyle, Christine Langer

JCI Insight· August 2017

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Polyfunctional and IFN- monofunctional human CD4 T cell populations are molecularly distinct.
Julie G Burel, Simon H Apte, Penny L Groves, James S McCarthy, Denise L Doolan

JCI Insight· February 2017

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Reduced Plasmodium Parasite Burden Associates with CD38+ CD4+ T Cells Displaying Cytolytic Potential and Impaired IFN-γ Production.
Julie G Burel, Simon H Apte, Penny L Groves, Kerenaftali Klein, James S McCarthy

PLoS Pathog· September 2016

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Chemically Attenuated Blood-Stage Plasmodium yoelii Parasites Induce Long-Lived and Strain-Transcending Protection.
Amber I Raja, Yeping Cai, Jennifer M Reiman, Penny Groves, Sumana Chakravarty

Infect Immun· August 2016

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Quantitative assessment of the functional plasticity of memory CD8(+) T cells.
Adriana Baz, Penny Groves, Kathy Buttigieg, Simon H Apte, Norbert Kienzle

Eur J Immunol· April 2016

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Systematic evaluation of self-adjuvanting lipopeptide nano-vaccine platforms for the induction of potent CD8(+) T-cell responses.
Simon H Apte, Rachel J Stephenson, Pavla Simerska, Penny L Groves, Salwa Aljohani

Nanomedicine (Lond)· January 2016

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Highly sensitive quantitative real-time PCR for the detection of Plasmodium liver-stage parasite burden following low-dose sporozoite challenge.
Sophie Schussek, Penny L Groves, Simon H Apte, Denise L Doolan

PLoS One· April 2014

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Subcutaneous cholera toxin exposure induces potent CD103⁺ dermal dendritic cell activation and migration.
Simon H Apte, Andrew M Redmond, Penny L Groves, Sophie Schussek, David J Pattinson

Eur J Immunol· October 2013

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Vaccination with lipid core peptides fails to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model.
Simon H Apte, Penny L Groves, Mariusz Skwarczynski, Yoshio Fujita, Chenghung Chang

PLoS One· April 2013

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Evaluation of approaches to identify the targets of cellular immunity on a proteome-wide scale.
Fernanda C Cardoso, Joanne S Roddick, Penny Groves, Denise L Doolan

PLoS One· April 2012

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High-throughput multi-parameter flow-cytometric analysis from micro-quantities of plasmodium-infected blood.
Simon H Apte, Penny L Groves, Joanne S Roddick, Vanusa P da Hora, Denise L Doolan

Int J Parasitol· October 2011

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IFN-gamma inhibits IL-4-induced type 2 cytokine expression by CD8 T cells in vivo and modulates the anti-tumor response.
Simon H Apte, Penny Groves, Stuart Olver, Adriana Baz, Denise L Doolan

J Immunol· July 2010

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Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells.
Simon H Apte, Adriana Baz, Penny Groves, Anne Kelso, Norbert Kienzle

Proc Natl Acad Sci U S A· November 2008

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Branched and linear lipopeptide vaccines have different effects on primary CD4+ and CD8+ T-cell activation but induce similar tumor-protective memory CD8+ T-cell responses.
Adriana Baz, Kathy Buttigieg, Weiguang Zeng, Michael Rizkalla, David C Jackson, Penny Groves

Vaccine· May 2008

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