Publications by authors named "Per-Olof Edlund"

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Improved identification of host cell proteins in a protein biopharmaceutical by LC-MS/MS using the ProteoMiner™ Enrichment Kit.
Harriet Mörtstedt, Åsa Makower, Per-Olof Edlund, Katarina Sjöberg, Agneta Tjernberg

J Pharm Biomed Anal· June 2020

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Robust LC-MS/MS methods for analysis of heparan sulfate levels in CSF and brain for application in studies of MPS IIIA.
Åsa Makower, Erik Arnelöf, Tommy Andersson, Per-Olof Edlund, Susanne Gustavsson

Bioanalysis· August 2019

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A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC.
Chao Su, Hjalmar Gullberg, Hanna Simko, Marguerite Luthman, Per-Olof Edlund

J Chromatogr B Analyt Technol Biomed Life Sci· September 2010

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Development of a two-dimensional liquid chromatography system for isolation of drug metabolites.
Mala Jayamanne, Ingrid Granelli, Agneta Tjernberg, Per-Olof Edlund

J Pharm Biomed Anal· February 2010

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Metabolism of 2-substituted quinolines with antileishmanial activity studied in vitro with liver microsomes, hepatocytes and recombinantly expressed enzymes analyzed by LC/MS.
Julie Desrivot, Per-Olof Edlund, Richard Svensson, Pawel Baranczewski, Alain Fournet

Toxicology· June 2007

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Introduction to early in vitro identification of metabolites of new chemical entities in drug discovery and development.
Paweł Baranczewski, Andrzej Stańczak, Antti Kautiainen, Per Sandin, Per-Olof Edlund

Pharmacol Rep· December 2006

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Characterization of the cytochrome P450 enzymes and enzyme kinetic parameters for metabolism of BVT.2938 using different in vitro systems.
Pawel Baranczewski, Per Olof Edlund, Hans Postlind

J Pharm Biomed Anal· March 2006

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Metabolic fingerprinting of rat urine by LC/MS Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry.
Helena Idborg, Leila Zamani, Per-Olof Edlund, Ina Schuppe-Koistinen, Sven P Jacobsson

J Chromatogr B Analyt Technol Biomed Life Sci· December 2005

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Metabolic fingerprinting of rat urine by LC/MS Part 2. Data pretreatment methods for handling of complex data.
Helena Idborg, Leila Zamani, Per-Olof Edlund, Ina Schuppe-Koistinen, Sven P Jacobsson

J Chromatogr B Analyt Technol Biomed Life Sci· December 2005

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Electrospray ionization mass spectrometry as a tool for determination of drug binding sites to human serum albumin by noncovalent interaction.
Kurt Benkestock, Per-Olof Edlund, Johan Roeraade

Rapid Commun Mass Spectrom· July 2005

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Determination of corticosteroids in tissue samples by liquid chromatography-tandem mass spectrometry.
Yuko Rönquist-Nii, Per Olof Edlund

J Pharm Biomed Anal· February 2005

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Influence of droplet size, capillary-cone distance and selected instrumental parameters for the analysis of noncovalent protein-ligand complexes by nano-electrospray ionization mass spectrometry.
Kurt Benkestock, Gustav Sundqvist, Per-Olof Edlund, Johan Roeraade

J Mass Spectrom· September 2004

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Determination of dissociation constants for protein-ligand complexes by electrospray ionization mass spectrometry.
Agneta Tjernberg, Sofi Carnö, Frida Oliv, Kurt Benkestock, Per-Olof Edlund

Anal Chem· August 2004

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Multivariate approaches for efficient detection of potential metabolites from liquid chromatography/mass spectrometry data.
Helena Idborg, Per-Olof Edlund, Sven P Jacobsson

Rapid Commun Mass Spectrom· May 2004

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Identification of BVT.2938 metabolites by LC/MS and LC/MS/MS after in vitro incubations with liver microsomes and hepatocytes.
Per Olof Edlund, Pawel Baranczewski

J Pharm Biomed Anal· March 2004

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Screening of biomarkers in rat urine using LC/electrospray ionization-MS and two-way data analysis.
Helena Idborg-Björkman, Per-Olof Edlund, Olav M Kvalheim, Ina Schuppe-Koistinen, Sven P Jacobsson

Anal Chem· September 2003

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Automated nano-electrospray mass spectrometry for protein-ligand screening by noncovalent interaction applied to human H-FABP and A-FABP.
Kurt Benkestock, Colleen K Van Pelt, Tomas Akerud, Alistair Sterling, Per-Olof Edlund

J Biomol Screen· June 2003

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On-line microdialysis for enhanced resolution and sensitivity during electrospray mass spectrometry of non-covalent complexes and competitive binding studies.
Kurt Benkestock, Per-Olof Edlund, Johan Roeraade

Rapid Commun Mass Spectrom· December 2002

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