Publications by authors named "Perihan Mir"

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Comparison of Gene-Editing Approaches for Severe Congenital Neutropenia-Causing Mutations in the Gene.
Malte Ulrich Ritter, Masoud Nasri, Benjamin Dannenmann, Perihan Mir, Benjamin Secker

CRISPR J· October 2024

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CRISPR-Cas9n-mediated ELANE promoter editing for gene therapy of severe congenital neutropenia.
Masoud Nasri, Malte U Ritter, Perihan Mir, Benjamin Dannenmann, Masako M Kaufmann

Mol Ther· June 2024

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Correction: NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells.
Yun Xu, Masoud Nasri, Benjamin Dannenmann, Perihan Mir, Azadeh Zahabi

Stem Cell Res Ther· October 2023

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iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia.
Benjamin Dannenmann, Maksim Klimiankou, Benedikt Oswald, Anna Solovyeva, Jehan Mardan, Perihan Mir, Miriam Erlacher

Cell Stem Cell· September 2023

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Corrigendum to 'Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34+ cells preceding leukemic transformation' <[Experimental Hematology, Volume 71, 2019;71:51-60]>.
Benjamin Dannenmann, Azadeh Zahabi, Perihan Mir, Benedikt Oswald, Regine Bernhard

Exp Hematol· October 2022

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A topological refactoring design strategy yields highly stable granulopoietic proteins.
Julia Skokowa, Birte Hernandez Alvarez, Murray Coles, Malte Ritter, Masoud Nasri, Perihan Mir

Nat Commun· May 2022

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iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia.
Benjamin Dannenmann, Maksim Klimiankou, Benedikt Oswald, Anna Solovyeva, Jehan Mardan, Perihan Mir, Miriam Erlacher

Cell Stem Cell· May 2021

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Gene Knockout in Hematopoietic Stem and Progenitor Cells Followed by Granulocytic Differentiation.
Perihan Mir, Malte Ritter, Karl Welte, Julia Skokowa, Maksim Klimiankou

Methods Mol Biol· February 2021

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NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells.
Yun Xu, Masoud Nasri, Benjamin Dannenmann, Perihan Mir, Azadeh Zahabi

Stem Cell Res Ther· February 2021

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Design of novel granulopoietic proteins by topological rescaffolding.
Birte Hernandez Alvarez, Julia Skokowa, Murray Coles, Perihan Mir, Masoud Nasri

PLoS Biol· December 2020

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New insights into the pathomechanism of cyclic neutropenia.
Perihan Mir, Maksim Klimiankou, Betuel Findik, Karin Hähnel, Sabine Mellor-Heineke

Ann N Y Acad Sci· April 2020

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CRISPR/Cas9-mediated knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients.
Masoud Nasri, Malte Ritter, Perihan Mir, Benjamin Dannenmann, Narges Aghaallaei

Haematologica· March 2020

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Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34 cells preceding leukemic transformation.
Benjamin Dannenmann, Azadeh Zahabi, Perihan Mir, Benedikt Oswald, Regine Bernhard

Exp Hematol· March 2019

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Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response.
Masoud Nasri, Perihan Mir, Benjamin Dannenmann, Diana Amend, Tessa Skroblyn

Blood Adv· January 2019

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GM-CSF treatment is not effective in congenital neutropenia patients due to its inability to activate NAMPT signaling.
Corinna Koch, Bardia Samareh, Tatsuya Morishima, Perihan Mir, Lothar Kanz

Ann Hematol· March 2017

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Molecular and functional interactions between AKT and SOX2 in breast carcinoma.
Thorsten Schaefer, Hui Wang, Perihan Mir, Martina Konantz, Tamara C Pereboom

Oncotarget· December 2015

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