Publications by authors named "Pernille Harris"

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Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism.
Yong Fan, Liwei Lyu, Ruben Vazquez-Uribe, Wanliang Zhang, Mareike Bongers, Pernille Harris

Nat Microbiol· August 2025

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design of a mechano-pharmaceutical screening platform against formation of individual beta-amyloid oligomers.
Shankar Pandey, Mathias Bogetoft Danielsen, Yuan Xiang, Zhilei Zhang, Grinsun Sharma, Pernille Harris

Cell Rep Phys Sci· December 2024

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Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide-Activated Sirtuin 7.
Julie E Bolding, Alexander L Nielsen, Iben Jensen, Tobias N Hansen, Line A Ryberg, Pernille Harris

Angew Chem Int Ed Engl· December 2023

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Streptomyces alleviate abiotic stress in plant by producing pteridic acids.
Zhijie Yang, Yijun Qiao, Naga Charan Konakalla, Emil Strøbech, Pernille Harris

Nat Commun· November 2023

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study of the interactions between acylated glucagon like-peptide-1 analogues and the native receptor.
Tine Maja Frimann, Suk Kyu Ko, Pernille Harris, Jens Thostrup Bukrinski, Günther H J Peters

J Biomol Struct Dyn· July 2023

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Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand.
Ida M Vedel, Andreas Prestel, Zhenwei Zhang, Natalia T Skawinska, Holger Stark, Pernille Harris

Structure· June 2023

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Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding.
Alina Kulakova, Dillen Augustijn, Inas El Bialy, Lorenzo Gentiluomo, Maria Laura Greco, Pernille Harris

Mol Pharm· June 2023

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Combining Molecular Dynamics Simulations and Biophysical Characterization to Investigate Protein-Specific Excipient Effects on Reteplase during Freeze Drying.
Suk Kyu Ko, Gabriella Björkengren, Carolin Berner, Gerhard Winter, Pernille Harris

Pharmaceutics· June 2023

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Dynamics of Human Serum Transferrin in Varying Physicochemical Conditions Explored by Using Molecular Dynamics Simulations.
Sowmya Indrakumar, Alina Kulakova, Pernille Harris, Günther H J Peters

Mol Pharm· August 2022

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pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils.
Christin Pohl, Gregory Effantin, Eaazhisai Kandiah, Sebastian Meier, Guanghong Zeng, Pernille Harris

Nat Commun· June 2022

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Investigation of the pH-dependent aggregation mechanisms of GCSF using low resolution protein characterization techniques and advanced molecular dynamics simulations.
Suk Kyu Ko, Carolin Berner, Alina Kulakova, Markus Schneider, Iris Antes, Pernille Harris

Comput Struct Biotechnol J· March 2022

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Combination of high throughput and structural screening to assess protein stability - A screening perspective.
Christin Pohl, Sujata Mahapatra, Alina Kulakova, Werner Streicher, Günther H J Peters, Pernille Harris

Eur J Pharm Biopharm· February 2022

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Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling.
Sujata Mahapatra, Marco Polimeni, Lorenzo Gentiluomo, Dierk Roessner, Wolfgang Frieß, Pernille Harris

Mol Pharm· February 2022

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Electrostatics Drive Oligomerization and Aggregation of Human Interferon Alpha-2a.
Christin Pohl, Marco Polimeni, Sowmya Indrakumar, Werner Streicher, Günther H J Peters, Pernille Harris

J Phys Chem B· December 2021

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A Multi-Method Approach to Assess the Self-Interaction Behavior of Infliximab.
Martin Domnowski, Takahiro Maruno, Kanta Enomoto, Felix Kummer, Alina Kulakova, Pernille Harris

J Pharm Sci· May 2021

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Development of a fast screening method for selecting excipients in formulations using MD simulations, NMR and microscale thermophoresis.
Sowmya Indrakumar, Matja Zalar, Nuska Tschammer, Christin Pohl, Allan Nørgaard, Pernille Harris

Eur J Pharm Biopharm· January 2021

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The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action.
Julia Weikum, Alina Kulakova, Giulio Tesei, Shogo Yoshimoto, Line Vejby Jægerum, Pernille Harris

Sci Rep· December 2020

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The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide: Development of a Screening Protocol for Peptide Stability Screening.
Christin Pohl, Matja Zalar, Inas El Bialy, Sowmya Indrakumar, Günther H J Peters, Pernille Harris

Mol Pharm· September 2020

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Albumin-neprilysin fusion protein: understanding stability using small angle X-ray scattering and molecular dynamic simulations.
Alina Kulakova, Sowmya Indrakumar, Pernille Sønderby Tuelung, Sujata Mahapatra, Werner W Streicher, Pernille Harris

Sci Rep· June 2020

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Isothermal Chemical Denaturation: Data Analysis, Error Detection, and Correction by PARAFAC2.
Dillen Augustijn, Alina Kulakova, Sujata Mahapatra, Pernille Harris, Åsmund Rinnan

Anal Chem· May 2020

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Concentrated protein solutions investigated using acoustic levitation and small-angle X-ray scattering.
Pernille Sønderby, Christopher Söderberg, Christian G Frankær, Günther Peters, Jens T Bukrinski, Pernille Harris

J Synchrotron Radiat· March 2020

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Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization.
Lorenzo Gentiluomo, Hristo L Svilenov, Dillen Augustijn, Inas El Bialy, Maria Laura Greco, Pernille Harris

Mol Pharm· February 2020

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Investigations of Albumin-Insulin Detemir Complexes Using Molecular Dynamics Simulations and Free Energy Calculations.
Line A Ryberg, Pernille Sønderby, Jens T Bukrinski, Pernille Harris, Günther H J Peters

Mol Pharm· January 2020

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Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin.
Alina Kulakova, Sowmya Indrakumar, Pernille Sønderby, Lorenzo Gentiluomo, Werner Streicher, Pernille Harris

J Struct Biol X· November 2019

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Use of F Differential Labelling for the Simultaneous Detection and Monitoring of Three Individual Proteins in a Serum Environment.
John M Edwards, Pernille Harris, Jens T Bukrinski, Alexander P Golovanov

Chempluschem· May 2019

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