Publications by authors named "Peter A Andreasen"

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Embelin ameliorated sepsis-induced disseminated intravascular coagulation intensities by simultaneously suppressing inflammation and thrombosis.
Dong Wang, Yongshuai Yang, Yu Wang, Valérie Proulle, Peter A Andreasen

Biomed Pharmacother· October 2020

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Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
Dong Wang, Yongshuai Yang, Longguang Jiang, Yu Wang, Jinyu Li, Peter A Andreasen

J Med Chem· February 2019

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Origin and diversification of the plasminogen activation system among chordates.
Andrés Chana-Muñoz, Agnieszka Jendroszek, Malene Sønnichsen, Tobias Wang, Michael Ploug, Peter A Andreasen

BMC Evol Biol· January 2019

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Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition.
Longguang Jiang, Emil Oldenburg, Tobias Kromann-Hansen, Peng Xu, Jan K Jensen, Peter A Andreasen

Biochim Biophys Acta Gen Subj· September 2018

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Crystal structure of plasma kallikrein reveals the unusual flexibility of the S1 pocket triggered by Glu217.
Mingming Xu, Yayu Chen, Peng Xu, Peter A Andreasen, Longguang Jiang

FEBS Lett· August 2018

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Structural Principles in the Development of Cyclic Peptidic Enzyme Inhibitors.
Peng Xu, Peter A Andreasen, Mingdong Huang

Int J Biol Sci· June 2018

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Ligand binding modulates the structural dynamics and activity of urokinase-type plasminogen activator: A possible mechanism of plasminogen activation.
Tobias Kromann-Hansen, Eva Louise Lange, Ida K Lund, Gunilla Høyer-Hansen, Peter A Andreasen

PLoS One· April 2018

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Multi-tissue RNA-seq and transcriptome characterisation of the spiny dogfish shark (Squalus acanthias) provides a molecular tool for biological research and reveals new genes involved in osmoregulation.
Andres Chana-Munoz, Agnieszka Jendroszek, Malene Sønnichsen, Rune Kristiansen, Jan K Jensen, Peter A Andreasen

PLoS One· October 2017

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Latency transition of plasminogen activator inhibitor type 1 is evolutionarily conserved.
Agnieszka Jendroszek, Malene S Sønnichsen, Andrés C Muñoz, Kato Leyman, Anni Christensen, Peter A Andreasen

Thromb Haemost· August 2017

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Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Tobias Kromann-Hansen, Eva Louise Lange, Hans Peter Sørensen, Gholamreza Hassanzadeh-Ghassabeh, Mingdong Huang, Peter A Andreasen

Sci Rep· June 2017

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A Conjugate of Two tPA-Binding RNA Aptamers Efficiently Inhibits Fibrinolysis.
Nils Bjerregaard, Daniel M Dupont, Peter A Andreasen

Nucleic Acid Ther· April 2017

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Expected and unexpected features of protein-binding RNA aptamers.
Nils Bjerregaard, Peter A Andreasen, Daniel M Dupont

Wiley Interdiscip Rev RNA· November 2016

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Urokinase links plasminogen activation and cell adhesion by cleavage of the RGD motif in vitronectin.
Valentina De Lorenzi, Gian Maria Sarra Ferraris, Jeppe B Madsen, Michela Lupia, Peter A Andreasen

EMBO Rep· July 2016

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Crystal Structure of a Two-domain Fragment of Hepatocyte Growth Factor Activator Inhibitor-1: FUNCTIONAL INTERACTIONS BETWEEN THE KUNITZ-TYPE INHIBITOR DOMAIN-1 AND THE NEIGHBORING POLYCYSTIC KIDNEY DISEASE-LIKE DOMAIN.
Zebin Hong, Laura De Meulemeester, Annemarie Jacobi, Jan Skov Pedersen, J Preben Morth, Peter A Andreasen

J Biol Chem· July 2016

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A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior.
Tobias Kromann-Hansen, Emil Oldenburg, Kristen Wing Yu Yung, Gholamreza H Ghassabeh, Serge Muyldermans, Peter A Andreasen

J Biol Chem· July 2016

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An RNA Aptamer Inhibits a Mutation-Induced Inactivating Misfolding of a Serpin.
Jeppe B Madsen, Lisbeth M Andersen, Daniel M Dupont, Morten B Trelle, Jesper S Johansen, Peter A Andreasen

Cell Chem Biol· June 2016

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Building a Molecular Trap for a Serine Protease from Aptamer and Peptide Modules.
Daniel M Dupont, Nils Bjerregaard, Ben Verpaalen, Peter A Andreasen, Jan K Jensen

Bioconjug Chem· April 2016

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Insights into the serine protease mechanism based on structural observations of the conversion of a peptidyl serine protease inhibitor to a substrate.
Longguang Jiang, Lisbeth Moreau Andersen, Peter A Andreasen, Liqing Chen, Mingdong Huang

Biochim Biophys Acta· March 2016

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Structural basis of specific inhibition of tissue-type plasminogen activator by plasminogen activators inhibitor-1.
Lihu Gong, Min Liu, Tu Zeng, Xiaoli Shi, Cai Yuan, Peter A Andreasen

Data Brief· March 2016

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Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo.
Kenneth A Botkjaer, Hang Fai Kwok, Mikkel G Terp, Aneesh Karatt-Vellatt, Salvatore Santamaria, Peter A Andreasen

Oncotarget· March 2016

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Characterisation of aptamer-target interactions by branched selection and high-throughput sequencing of SELEX pools.
Daniel M Dupont, Niels Larsen, Jan K Jensen, Peter A Andreasen, Jørgen Kjems

Nucleic Acids Res· December 2015

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Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein Inhibitor.
Peng Xu, Mingming Xu, Longguang Jiang, Qinglan Yang, Zhipu Luo, Peter A Andreasen

J Med Chem· November 2015

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Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1.
Lihu Gong, Min Liu, Tu Zeng, Xiaoli Shi, Cai Yuan, Peter A Andreasen

J Biol Chem· October 2015

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Selection of High-Affinity Peptidic Serine Protease Inhibitors with Increased Binding Entropy from a Back-Flip Library of Peptide-Protease Fusions.
Hans Peter Sørensen, Peng Xu, Longguang Jiang, Tobias Kromann-Hansen, Knud J Jensen, Peter A Andreasen

J Mol Biol· September 2015

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Tissue-type plasminogen activator-binding RNA aptamers inhibiting low-density lipoprotein receptor family-mediated internalisation.
Nils Bjerregaard, Kenneth A Bøtkjær, Nicky Helsen, Peter A Andreasen, Daniel M Dupont

Thromb Haemost· July 2015

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