Publications by authors named "Peter A Keyel"

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Vav2 is a master regulator of repair against bacterial pore-forming toxins.
Victor Gbenga Kayejo, Ashlee Hensley, Tejal Katore, Peter A Keyel

bioRxiv· August 2025

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The fungal peptide toxin candidalysin induces distinct membrane repair mechanisms compared to bacterial pore-forming toxins.
Roshan Thapa, Victor Kayejo, Bernhard Hube, Julian R Naglik, Peter A Keyel

bioRxiv· May 2025

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Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice.
Minal Engavale, Colton J Hernandez, Angelica Infante, Tanya LeRoith, Elliott Radovan, Peter A Keyel

J Leukoc Biol· November 2023

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Translational implications of targeting annexin A2: From membrane repair to muscular dystrophy, cardiovascular disease and cancer.
Victor G Kayejo, Hannah Fellner, Roshan Thapa, Peter A Keyel

Clin Transl Discov· October 2023

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The sphingolipids ceramide and inositol phosphorylceramide protect the Leishmania major membrane from sterol-specific toxins.
Chaitanya S Haram, Samrat Moitra, Rilee Keane, F Matthew Kuhlmann, Cheryl Frankfater, Peter A Keyel

J Biol Chem· June 2023

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Pathogenic Mutations in the C2A Domain of Dysferlin form Amyloid that Activates the Inflammasome.
Isaac L Scott, Matthew J Dominguez, Adam Snow, Faraz M Harsini, Justin Williams, Peter A Keyel

bioRxiv· May 2023

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Patch repair protects cells from the small pore-forming toxin aerolysin.
Roshan Thapa, Peter A Keyel

J Cell Sci· April 2023

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Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice.
Minal Engavale, Colton J Hernandez, Angelica Infante, Tanya LeRoith, Elliott Radovan, Peter A Keyel

bioRxiv· April 2023

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Deciphering the Molecular Mechanism and Function of Pore-Forming Toxins using Leishmania major.
Chaitanya S Haram, Samrat Moitra, Rilee Keane, Elana Breslav, Kai Zhang, Peter A Keyel

J Vis Exp· October 2022

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Structural features of Dnase1L3 responsible for serum antigen clearance.
Jon J McCord, Minal Engavale, Elahe Masoumzadeh, Johanna Villarreal, Britney Mapp, Peter A Keyel

Commun Biol· August 2022

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Membrane repair triggered by cholesterol-dependent cytolysins is activated by mixed lineage kinases and MEK.
Sucharit Ray, Robyn Roth, Peter A Keyel

Sci Adv· March 2022

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Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity.
Yujiao Zu, Ling Zhao, Lei Hao, Yehia Mechref, Masoud Zabet-Moghaddam, Peter A Keyel

J Control Release· May 2021

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Interaction of Macrophages and Cholesterol-Dependent Cytolysins: The Impact on Immune Response and Cellular Survival.
Roshan Thapa, Sucharit Ray, Peter A Keyel

Toxins (Basel)· August 2020

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Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins.
Sucharit Ray, Roshan Thapa, Peter A Keyel

Toxins (Basel)· December 2018

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Cholesterol-dependent cytolysins impair pro-inflammatory macrophage responses.
Pushpak Bhattacharjee, Peter A Keyel

Sci Rep· April 2018

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Dnases in health and disease.
Peter A Keyel

Dev Biol· September 2017

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Intrinsic repair protects cells from pore-forming toxins by microvesicle shedding.
Matthew Romero, Michelle Keyel, Guilan Shi, Pushpak Bhattacharjee, Robyn Roth, Peter A Keyel

Cell Death Differ· May 2017

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Dnase1L3 Regulates Inflammasome-Dependent Cytokine Secretion.
Guilan Shi, Kennady N Abbott, Wenbo Wu, Russell D Salter, Peter A Keyel

Front Immunol· May 2017

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Methylthioadenosine reprograms macrophage activation through adenosine receptor stimulation.
Peter A Keyel, Matthew Romero, Wenbo Wu, Daniel H Kwak, Qin Zhu

PLoS One· April 2015

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How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1.
Peter A Keyel

Cytokine· September 2014

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The second transmembrane domain of P2X7 contributes to dilated pore formation.
Chengqun Sun, Michelle E Heid, Peter A Keyel, Russell D Salter

PLoS One· November 2013

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Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation.
Michelle E Heid, Peter A Keyel, Christelle Kamga, Sruti Shiva, Simon C Watkins

J Immunol· November 2013

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Reduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation.
Peter A Keyel, Robyn Roth, Wayne M Yokoyama, John E Heuser, Russell D Salter

Toxins (Basel)· June 2013

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Coordinate stimulation of macrophages by microparticles and TLR ligands induces foam cell formation.
Peter A Keyel, Olga A Tkacheva, Adriana T Larregina, Russell D Salter

J Immunol· November 2012

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Visualization of bacterial toxin induced responses using live cell fluorescence microscopy.
Peter A Keyel, Michelle E Heid, Simon C Watkins, Russell D Salter

J Vis Exp· October 2012

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