Publications by authors named "Peter Arhem"

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Ligand with Two Modes of Interaction with the Dopamine D Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism.
Richard Ågren, Hugo Zeberg, Tomasz Maciej Stępniewski, R Benjamin Free, Sean W Reilly

ACS Chem Neurosci· October 2020

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Closed and open state dependent block of potassium channels cause opposing effects on excitability - a computational approach.
Richard Ågren, Johanna Nilsson, Peter Århem

Sci Rep· June 2019

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The Beta-Arrestin-Biased Dopamine D2 Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation.
Richard Ågren, Peter Århem, Johanna Nilsson, Kristoffer Sahlholm

Int J Neuropsychopharmacol· December 2018

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The Importance of the Dissociation Rate in Ion Channel Blocking.
Hugo Zeberg, Johanna Nilsson, Peter Århem

Front Cell Neurosci· February 2018

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Point mutation of a conserved aspartate, D69, in the muscarinic M receptor does not modify voltage-sensitive agonist potency.
Richard Ågren, Kristoffer Sahlholm, Johanna Nilsson, Peter Århem

Biochem Biophys Res Commun· January 2018

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Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1.
Fredrik Elinder, Michael Madeja, Hugo Zeberg, Peter Århem

Biophys J· October 2016

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The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor.
Kristoffer Sahlholm, Hugo Zeberg, Johanna Nilsson, Sven Ove Ögren, Kjell Fuxe

Eur Neuropsychopharmacol· March 2016

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G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy.
Chuang Lyu, Jan Mulder, Swapnali Barde, Kristoffer Sahlholm, Hugo Zeberg

Mol Pain· July 2015

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Density of voltage-gated potassium channels is a bifurcation parameter in pyramidal neurons.
Hugo Zeberg, Hugh P C Robinson, Peter Århem

J Neurophysiol· January 2015

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Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor.
Kristoffer Sahlholm, Daniel Marcellino, Johanna Nilsson, Sven Ove Ögren, Kjell Fuxe

Int J Neuropsychopharmacol· January 2014

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Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model.
Tie-Jun Sten Shi, Ming-Dong Zhang, Hugo Zeberg, Johanna Nilsson, Jacob Grünler, Peter Arhem

Proc Natl Acad Sci U S A· January 2013

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Voltage sensitivities and deactivation kinetics of histamine H₃ and H₄ receptors.
Kristoffer Sahlholm, Johanna Nilsson, Daniel Marcellino, Kjell Fuxe, Peter Arhem

Biochim Biophys Acta· December 2012

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Agonist-specific voltage sensitivity at the dopamine D2S receptor--molecular determinants and relevance to therapeutic ligands.
Kristoffer Sahlholm, Ofra Barchad-Avitzur, Daniel Marcellino, Maricel Gómez-Soler, Kjell Fuxe, Peter Arhem

Neuropharmacology· February 2012

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Spontaneous ryanodine-receptor-dependent Ca2+-activated K+ currents and hyperpolarizations in rat medial preoptic neurons.
Göran Klement, Michael Druzin, David Haage, Evgenya Malinina, Peter Arhem

J Neurophysiol· May 2010

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Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer.
Daniel Marcellino, Gemma Navarro, Kristoffer Sahlholm, Johanna Nilsson, Luigi F Agnati

Biochem Biophys Res Commun· April 2010

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Ion channel density regulates switches between regular and fast spiking in soma but not in axons.
Hugo Zeberg, Clas Blomberg, Peter Arhem

PLoS Comput Biol· April 2010

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Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics.
Johanna Nilsson, Michael Madeja, Fredrik Elinder, Peter Arhem

Biophys J· December 2008

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Voltage-sensitivity at the human dopamine D2S receptor is agonist-specific.
Kristoffer Sahlholm, Daniel Marcellino, Johanna Nilsson, Kjell Fuxe, Peter Arhem

Biochem Biophys Res Commun· December 2008

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Electrophysiology-based analysis of human histamine H(4) receptor pharmacology using GIRK channel coupling in Xenopus oocytes.
Kristoffer Sahlholm, Johanna Nilsson, Daniel Marcellino, Kjell Fuxe, Peter Arhem

Eur J Pharmacol· September 2008

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Differential voltage-sensitivity of D2-like dopamine receptors.
Kristoffer Sahlholm, Daniel Marcellino, Johanna Nilsson, Kjell Fuxe, Peter Arhem

Biochem Biophys Res Commun· September 2008

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Voltage-dependence of the human dopamine D2 receptor.
Kristoffer Sahlholm, Johanna Nilsson, Daniel Marcellino, Kjell Fuxe, Peter Arhem

Synapse· June 2008

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A tyrosine substitution in the cavity wall of a k channel induces an inverted inactivation.
Göran Klement, Johanna Nilsson, Peter Arhem, Fredrik Elinder

Biophys J· April 2008

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On the opening of voltage-gated ion channels.
Fredrik Elinder, Johanna Nilsson, Peter Arhem

Physiol Behav· September 2007

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The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes.
Kristoffer Sahlholm, Johanna Nilsson, Daniel Marcellino, Kjell Fuxe, Peter Arhem

Eur J Pharmacol· July 2007

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Ion channel density and threshold dynamics of repetitive firing in a cortical neuron model.
Peter Arhem, Clas Blomberg

Biosystems· June 2007

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