Publications by authors named "Peter Arvan"

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The structure of natively iodinated bovine thyroglobulin.
Kookjoo Kim, Mykhailo Kopylov, Daija Bobe, Kotaro Kelley, Edward T Eng, Peter Arvan, Oliver B Clarke

Acta Crystallogr D Struct Biol· November 2021

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Stimulated thyroid hormone synthesis machinery drives thyrocyte cell death independent of ER stress.
Crystal Young, Xiaohan Zhang, Xiaofan Wang, Aaron P Kellogg, Kevin Pena, Peter Arvan

J Clin Invest· December 2025

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Recessive TMEM167A variants cause neonatal diabetes, microcephaly, and epilepsy syndrome.
Enrico Virgilio, Sylvia Tielens, Georgia Bonfield, Fang-Shin Nian, Toshiaki Sawatani, Peter Arvan

J Clin Invest· November 2025

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Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis.
Anoop Arunagiri, Leena Haataja, Maroof Alam, Noah F Gleason, Emma Mastroianni, Peter Arvan

J Clin Invest· November 2025

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Thyroidal expression of ER molecular chaperone GRP170 is required for efficient TSH-mediated thyroid hormone synthesis.
Xiaohan Zhang, Crystal Young, Xiao-Hui Liao, Samuel Refetoff, Stephanie M Mutchler, Peter Arvan

JCI Insight· September 2025

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Trapα deficiency impairs the early events of insulin biosynthesis and glucose homeostasis.
Xin Li, Jingxin Hu, Yumeng Huang, Hai Zhang, Ning Xu, Peter Arvan

J Clin Invest· July 2025

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A Genetically-Engineered Thyroid Gland Built for Selective Triiodothyronine Secretion.
Cintia E Citterio, Berenice Morales-Rodriguez, Xiao-Hui Liao, Catherine Vu, Rachel Nguyen, Peter Arvan

Int J Mol Sci· July 2025

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Quantification of Folded and Misfolded Proinsulin Forms Using Nonreducing SDS-PAGE and Proinsulin-Specific Immunoblotting.
Anoop Arunagiri, Insook Jang, Pamela Itkin-Ansari, Randal J Kaufman, Peter Arvan

Bio Protoc· June 2025

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Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues.
Emily M Walker, Gemma L Pearson, Nathan Lawlor, Ava M Stendahl, Anne Lietzke, Peter Arvan

Science· April 2025

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Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation.
Bhaskar K Chatterjee, Maroof Alam, Arghya Chakravorty, Shannon M Lacy, William Giblin, Peter Arvan

ACS Chem Biol· April 2025

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An Essential Role of IER3IP1 in β-Cell Development and Proinsulin Trafficking.
Wenli Feng, Peter Arvan, Ming Liu

Diabetes· April 2025

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FVB But Not B6 Mice Carrying the Thr92Ala-Dio2 Polymorphism Have Impaired Thyroid Hormonogenesis and Goiter.
Alice Batistuzzo, Xiaohan Zhang, Barbara M L C Bocco, Elizabeth A McAninch, Federico Salas-Lucia, Peter Arvan

Endocrinology· March 2025

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SEL1L-HRD1 ER-Associated Degradation Facilitates Prohormone Convertase 2 Maturation and Glucagon Production in Islet α Cells.
Wenzhen Zhu, Linxiu Pan, Xianwei Cui, Anna Chiara Russo, Rohit Ray, Peter Arvan

bioRxiv· March 2025

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Role of Sec61α2 Translocon in Insulin Biosynthesis.
Xiaoxi Xu, Thomas W Bell, Truc Le, Ivy Zhao, Emily Walker, Peter Arvan

Diabetes· December 2024

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Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway.
Rita A Avelar, Riya Gupta, Grace Carvette, Felipe da Veiga Leprevost, Medhasri Jasti, Peter Arvan

Cell Death Differ· December 2024

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SIGMAR1/Sigma-1 receptor: a key regulator in stabilizing and translating mRNA for autophagosome formation.
Yu-Jie Chen, Jeffrey Knupp, Emily Wang, Peter Arvan, Billy Tsai

Autophagy· December 2024

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Untangling the genetics of beta cell dysfunction and death in type 1 diabetes.
Catherine C Robertson, Ruth M Elgamal, Belle A Henry-Kanarek, Peter Arvan, Shuibing Chen

Mol Metab· August 2024

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Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy.
Jeffrey Knupp, Yu-Jie Chen, Emily Wang, Peter Arvan, Billy Tsai

Cell Rep· August 2024

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Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation.
Bhaskar K Chatterjee, Maroof Alam, Arghya Chakravorty, Shannon M Lacy, Jason Rech, Peter D Arvan

bioRxiv· July 2024

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Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Anoop Arunagiri, Maroof Alam, Leena Haataja, Hassan Draz, Bashiyer Alasad, Peter Arvan

Protein Sci· April 2024

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Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway.
Rita A Avelar, Riya Gupta, Gracie Carvette, Felipe da Veiga Leprevost, Jose Colina, Peter Arvan

Res Sq· March 2024

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Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity.
Yuwei Zhang, Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Peter Arvan

Mol Metab· February 2024

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Autophagy of the ER: the secretome finds the lysosome.
Jeffrey Knupp, Madison L Pletan, Peter Arvan, Billy Tsai

FEBS J· December 2023

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SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.
Hitoshi Iida, Tatsuyoshi Kono, Chih-Chun Lee, Preethi Krishnan, Matthew C Arvin, Peter Arvan

Diabetologia· November 2023

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Structural features of thyroglobulin linked to protein trafficking.
Cintia E Citterio, Kookjoo Kim, Bhavana Rajesh, Kevin Pena, Oliver Biggs Clarke, Peter Arvan

Protein Sci· November 2023

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Permanent Neonatal diabetes-causing Insulin mutations have dominant negative effects on beta cell identity.
Yuwei Zhang, Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Peter Arvan

bioRxiv· September 2023

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