Publications by authors named "Peter B Ehmer"

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Simultaneous measurement of metabolic stability and metabolite identification of 7-methoxymethylthiazolo[3,2-a]pyrimidin-5-one derivatives in human liver microsomes using liquid chromatography/ion-trap mass spectrometry.
E Kantharaj, Peter B Ehmer, An Tuytelaars, Anne Van Vlaslaer, Claire Mackie

Rapid Commun Mass Spectrom· June 2005

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The use of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry to explore the in vitro metabolism of cyanoalkyl piperidine derivatives.
E Kantharaj, Peter B Ehmer, Katie De Wagter, An Tuytelaars, Pascale E A Proost

Biomed Chromatogr· April 2005

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Synthesis of hydroxy derivatives of highly potent non-steroidal CYP 17 inhibitors as potential metabolites and evaluation of their activity by a non cellular assay using recombinant human enzyme.
Tilman U Hutschenreuter, Peter B Ehmer, Rolf W Hartmann

J Enzyme Inhib Med Chem· February 2004

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Discovery of selective CYP11B2 (aldosterone synthase) inhibitors for the therapy of congestive heart failure and myocardial fibrosis.
Rolf W Hartmann, Ursula Müller, Peter B Ehmer

Eur J Med Chem· April 2003

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Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo.
Samer Haidar, Peter B Ehmer, Stephan Barassin, Christine Batzl-Hartmann, Rolf W Hartmann

J Steroid Biochem Mol Biol· April 2003

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Development of a test system for inhibitors of human aldosterone synthase (CYP11B2): screening in fission yeast and evaluation of selectivity in V79 cells.
Peter B Ehmer, Matthias Bureik, Rita Bernhardt, Ursula Müller, Rolf W Hartmann

J Steroid Biochem Mol Biol· June 2002

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Inhibition of CYP 17, a new strategy for the treatment of prostate cancer.
Rolf W Hartmann, Peter B Ehmer, Samer Haidar, Markus Hector, Joachim Jose

Arch Pharm (Weinheim)· April 2002

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