Publications by authors named "Peter B Stathopulos"

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Defining the interactome of the pancreas-specific SPCA2 isoform (SPCA2C) identifies unique links to store-operated Ca entry.
Petra Samardzija, Melissa A Fenech, Oneeb Hassan, Ryann Lang, McKenzie C Carter, Peter B Stathopulos

FEBS J· December 2025

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Protocol for deriving distance restraints from AlphaFold for use in solution NMR structure determination.
Qi-Tong Lin, Peter B Stathopulos

STAR Protoc· September 2025

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Skin disease-associated GJB4 variants differentially influence connexin stability, cell viability and channel function.
Sergiu A Lucaciu, Stephanie E Leighton, Robert S Wong, Varun Sekar, Alexandra Hauser, Peter B Stathopulos

J Physiol· August 2025

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The apo LETM1 F-EF-hand adopts a closed conformation that underlies a multi-modal sensory role in mitochondria.
Qi-Tong Lin, Danielle M Colussi, Peter B Stathopulos

FEBS Lett· April 2025

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Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb.
Danielle M Colussi, Ryan Grainger, Megan Noble, Taylor Lake, Murray Junop, Peter B Stathopulos

Comput Struct Biotechnol J· December 2024

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An AI-informed NMR structure reveals an extraordinary LETM1 F-EF-hand domain that functions as a two-way regulator of mitochondrial calcium.
Qi-Tong Lin, Danielle M Colussi, Taylor Lake, Peter B Stathopulos

Structure· November 2024

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MRS2 missense variation at Asp216 abrogates inhibitory Mg binding, potentiating cell migration and apoptosis resistance.
Sukanthathulse Uthayabalan, Taylor Lake, Peter B Stathopulos

Protein Sci· August 2024

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The mitochondrial calcium uniporter: Balancing tumourigenic and anti-tumourigenic responses.
Danielle M Colussi, Peter B Stathopulos

J Physiol· July 2024

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The MCU and MCUb amino-terminal domains tightly interact: mechanisms for low conductance assembly of the mitochondrial calcium uniporter complex.
Megan Noble, Danielle M Colussi, Murray Junop, Peter B Stathopulos

iScience· May 2024

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Essential role of N-terminal SAM regions in STIM1 multimerization and function.
Matthias Sallinger, Christina Humer, Hwei Ling Ong, Sasirekha Narayanasamy, Qi Tong Lin, Peter B Stathopulos

Proc Natl Acad Sci U S A· May 2024

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ERMA (TMEM94) is a P-type ATPase transporter for Mg uptake in the endoplasmic reticulum.
Neelanjan Vishnu, Manigandan Venkatesan, Travis R Madaris, Mridula K Venkateswaran, Kristen Stanley, Peter B Stathopulos

Mol Cell· April 2024

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Cx31.1 can selectively intermix with co-expressed connexins to facilitate its assembly into gap junctions.
Stephanie E Leighton, Robert S Wong, Sergiu A Lucaciu, Alexandra Hauser, Danielle Johnston, Peter B Stathopulos

J Cell Sci· April 2024

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Acetylenic tricyclic bis-(cyano enone) interacts with Cys 374 of actin, a residue necessary for stress fiber formation and cell migration.
Eddie Chan, Brennan S Dirk, Tadashi Honda, Peter B Stathopulos, Jimmy D Dikeakos

Biochim Biophys Acta Mol Cell Res· February 2024

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Human Cx50 Isoleucine177 prevents heterotypic docking and formation of functional gap junction channels with Cx43.
Robert S Wong, Honghong Chen, Yi X Li, Jessica L Esseltine, Peter B Stathopulos

Am J Physiol Cell Physiol· February 2024

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Aromatically stacking the odds in favour of increased ORAI1 activation.
Peter B Stathopulos, Mitsuhiko Ikura

Cell Calcium· January 2024

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Inherited disease-linked arginine76/75 mutants in Cx50 and Cx45 showed impaired homotypic and heterotypic gap junction function, but not Cx43.
Tianhe Li, Honghong Chen, Xiaole Li, Peter B Stathopulos, Donglin Bai

Biochem J· July 2023

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The human MRS2 magnesium-binding domain is a regulatory feedback switch for channel activity.
Sukanthathulse Uthayabalan, Neelanjan Vishnu, Muniswamy Madesh, Peter B Stathopulos

Life Sci Alliance· April 2023

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Limiting Mrs2-dependent mitochondrial Mg uptake induces metabolic programming in prolonged dietary stress.
Travis R Madaris, Manigandan Venkatesan, Soumya Maity, Miriam C Stein, Neelanjan Vishnu, Peter B Stathopulos

Cell Rep· March 2023

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From passage to inhibition: Uncovering the structural and physiological inhibitory mechanisms of MCUb in mitochondrial calcium regulation.
Danielle M Colussi, Peter B Stathopulos

FASEB J· January 2023

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An S-glutathiomimetic Provides Structural Insights into Stromal Interaction Molecule-1 Regulation.
Christian Sirko, Matthew J Novello, Peter B Stathopulos

J Mol Biol· December 2022

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The Hydrophobic Residues in Amino Terminal Domains of Cx46 and Cx50 Are Important for Their Gap Junction Channel Ion Permeation and Gating.
Roa'a Jaradat, Xiaole Li, Honghong Chen, Peter B Stathopulos, Donglin Bai

Int J Mol Sci· October 2022

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An Amino Acid Polymorphism within the HIV-1 Nef Dileucine Motif Functionally Uncouples Cell Surface CD4 and SERINC5 Downregulation.
Mitchell J Mumby, Aaron L Johnson, Steven M Trothen, Cassandra R Edgar, Richard Gibson, Peter B Stathopulos

J Virol· July 2021

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Differential Domain Distribution of gnomAD- and Disease-Linked Connexin Missense Variants.
Donglin Bai, Jiayi Wang, Tianhe Li, Ryan Chan, Mena Atalla, Peter B Stathopulos

Int J Mol Sci· July 2021

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The leucine zipper EF-hand containing transmembrane protein-1 EF-hand is a tripartite calcium, temperature, and pH sensor.
Qi-Tong Lin, Rachel Lee, Allen L Feng, Michael S Kim, Peter B Stathopulos

Protein Sci· April 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Peter B Stathopulos

Autophagy· January 2021

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