Publications by authors named "Peter Bretscher"

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On the nature of signal 1 delivered to lymphocytes: A critical response to some considerations put forward in support of the quantum model of T cell activation.
Peter A Bretscher

Scand J Immunol· February 2025

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The information overload, immunology and their relationship to world health.
Peter A Bretscher

Open Biol· January 2025

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Internal regulation between constitutively expressed T cell co-inhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants.
Adeolu O Adegoke, Govindarajan Thangavelu, Ting-Fang Chou, Marcos I Petersen, Kiyokazu Kakugawa, Peter A Bretscher

Open Biol· October 2024

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A Plausible Framework Reveals Potential Similarities in the Regulation of Immunity against Some Cancers and Some Infectious Agents: Implications for Prevention and Treatment.
Peter A Bretscher

Cancers (Basel)· April 2024

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Are There General Features of How Immune Responses Are Regulated That Can Provide Clues to How Remitting/Relapsing Multiple Sclerosis May Be Treated?
Peter Alan Bretscher

Int J Mol Sci· February 2024

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Relapsing/remitting multiple sclerosis: A speculative model and its implications for a novel treatment.
Peter Bretscher

Scand J Immunol· November 2023

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What Determines the Class of Immunity an Antigen Induces? A Foundational Question Whose Rational Consideration Has Been Undermined by the Information Overload.
Peter Bretscher

Biology (Basel)· September 2023

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On antigen-specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation.
Colin C Anderson, Elizabeth A Bonney, Thomas F Mueller, Alexandre Corthay, Calliopi Havele, Peter A Bretscher

Scand J Immunol· September 2023

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The Problem of Host and Pathogen Genetic Variability for Developing Strategies of Universally Efficacious Vaccination against and Personalised Immunotherapy of Tuberculosis: Potential Solutions?
Peter A Bretscher

Int J Mol Sci· January 2023

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Analyzing some concepts of immune regulation of the last three decades: Fostering greater research resilience despite the information overload. A personal view.
Peter A Bretscher

Front Immunol· November 2022

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Information overload and resilience in facing foundational issues.
Peter Bretscher

Proc Natl Acad Sci U S A· March 2022

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Facing the Increased Prevalence of Antibiotic-Resistant : Exploring the Feasibility of Realising Koch's Aspiration of Immunotherapy of Tuberculosis.
Peter A Bretscher

Antibiotics (Basel)· March 2022

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Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis.
Federica Piattini, Mai Matsushita, Jonathan Muri, Peter Bretscher, Xiaogang Feng

Eur J Immunol· October 2021

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The historical postulate: Is it the basis, at the level of the system, for self-nonself discrimination?
Peter A Bretscher

Scand J Immunol· August 2021

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Can interruption/withdrawl of anti-retroviral therapy provide personalized immunotherapy against HIV-1?
Peter A Bretscher, Ghassan Al-Yassin

Scand J Immunol· December 2020

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On Analyzing How the Th1/Th2 Phenotype of an Immune Response Is Determined: Classical Observations Must Not Be Ignored.
Peter Bretscher

Front Immunol· October 2020

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On T cell development, T cell signals, T cell specificity and sensitivity, and the autoimmunity facilitated by lymphopenia.
Peter A Bretscher, Ghassan Al-Yassin, Colin C Anderson

Scand J Immunol· June 2020

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On how the immune system preferentially interacts with antigen-specific molecules bound to antigen over unbound molecules, with emphasis on B cell receptor signalling.
Peter A Bretscher, Ghassan A Al-Yassin

Scand J Immunol· September 2019

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The history of the two-signal model of lymphocyte activation: A personal perspective.
Peter A Bretscher

Scand J Immunol· June 2019

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Does T Cell Activation Require a Quorum of Lymphocytes?
Ghassan A Al-Yassin, Peter A Bretscher

J Immunol· November 2018

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Is the Framework of Cohn's 'Tritope Model' for How T Cell Receptors Recognize Peptide/Self-MHC Complexes and Allo-MHC Plausible?
Peter A Bretscher

Scand J Immunol· May 2016

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Total Synthesis of Prostaglandin 15d-PGJ(2) and Investigation of its Effect on the Secretion of IL-6 and IL-12.
Julian Egger, Stefan Fischer, Peter Bretscher, Stefan Freigang, Manfred Kopf

Org Lett· September 2015

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Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2.
Peter Bretscher, Julian Egger, Abdijapar Shamshiev, Martin Trötzmüller, Harald Köfeler

EMBO Mol Med· May 2015

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Discovery of a highly potent anti-inflammatory epoxyisoprostane-derived lactone.
Julian Egger, Peter Bretscher, Stefan Freigang, Manfred Kopf, Erick M Carreira

J Am Chem Soc· December 2014

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The number of responding CD4 T cells and the dose of antigen conjointly determine the TH1/TH2 phenotype by modulating B7/CD28 interactions.
Christopher D Rudulier, K Kai McKinstry, Ghassan A Al-Yassin, David R Kroeger, Peter A Bretscher

J Immunol· June 2014

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