Publications by authors named "Peter Dorff"

Claim this Profile
D
Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer's Disease.
Martin Pettersson, Douglas S Johnson, John M Humphrey, Christopher W Am Ende, Todd W Butler, Peter H Dorff

J Med Chem· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Deprotection of N-Boc Groups under Continuous-Flow High-Temperature Conditions.
Bryan Li, Ruizhi Li, Peter Dorff, J Christopher McWilliams, Robert M Guinn

J Org Chem· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis of three alpha 7 agonists in labeled form.
Charles S Elmore, Scott Landvatter, Peter N Dorff, Mark E Powell, David Killick

J Labelled Comp Radiopharm· May 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Radiochemical synthesis and in vivo evaluation of [18F]AZ11637326: an agonist probe for the α7 nicotinic acetylcholine receptor.
Hayden T Ravert, Peter Dorff, Catherine A Foss, Ronnie C Mease, Hong Fan

Nucl Med Biol· August 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and optimization of a novel spiropyrrolidine inhibitor of β-secretase (BACE1) through fragment-based drug design.
Ivan V Efremov, Felix F Vajdos, Kris A Borzilleri, Steven Capetta, Hou Chen, Peter H Dorff

J Med Chem· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metabolism of a G protein-coupled receptor modulator, including two major 1,2,4-oxadiazole ring-opened metabolites and a rearranged cysteine-piperazine adduct.
Chungang Gu, Charles S Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff

Drug Metab Dispos· June 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Application of the bicyclo[1.1.1]pentane motif as a nonclassical phenyl ring bioisostere in the design of a potent and orally active γ-secretase inhibitor.
Antonia F Stepan, Chakrapani Subramanyam, Ivan V Efremov, Jason K Dutra, Theresa J O'Sullivan, Peter H Dorff

J Med Chem· April 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metabolism-directed design of oxetane-containing arylsulfonamide derivatives as γ-secretase inhibitors.
Antonia F Stepan, Kapil Karki, W Scott McDonald, Peter H Dorff, Jason K Dutra

J Med Chem· November 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes.
Neil Vasdev, Peter N Dorff, James P O'Neil, Frederick T Chin, Stephen Hanrahan

Bioorg Med Chem· May 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Absence of direct effects on the dopamine D2 receptor by mGluR2/3-selective receptor agonists LY 354,740 and LY 379,268.
John R Zysk, Dan Widzowski, Linda A Sygowski, Katharine S Knappenberger, Nathan Spear, Peter Dorff

Synapse· January 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro assessment of metabolic drug–drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through cytochrome P(450) enzyme identification, inhibition, and induction studies.
Yan Li, Diansong Zhou, Stephen S Ferguson, Peter Dorff, Thomas R Simpson

Xenobiotica· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
D2 receptor occupancy in conscious rat brain is not significantly distinguished with [3H]-MNPA, [3H]-(+)-PHNO, and [3H]-raclopride.
Teng Peng, John Zysk, Peter Dorff, Charles S Elmore, Peter Ström

Synapse· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A new strategy for preparing molecular imaging and therapy agents using fluorine-rich (fluorous) soluble supports.
Amanda Donovan, Jane Forbes, Peter Dorff, Paul Schaffer, John Babich

J Am Chem Soc· March 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potent small molecule CCR1 antagonists.
John C Kath, William H Brissette, Matthew F Brown, Maryrose Conklyn, Amy P DiRico, Peter Dorff

Bioorg Med Chem Lett· May 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis