Publications by authors named "Peter J Flor"

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Novel Inhibitory Site Revealed by Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Nunzia Cristiano, Alexandre Cabayé, Isabelle Brabet, Ralf Glatthar, Amelie Tora, Peter J Flor

J Med Chem· July 2024

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Blocking Metabotropic Glutamate Receptor Subtype 7 via the Venus Flytrap Domain Promotes a Chronic Stress-Resilient Phenotype in Mice.
Karolyne A R Estrela, Lisa Senninger, Josephine Arndt, Melanie Kabas, Ferdinand Schmid, Peter J Flor

Cells· June 2022

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Metabotropic glutamate receptor subtype 7 controls maternal care, maternal motivation and maternal aggression in mice.
Katharina Gryksa, Laura Mittmann, Angelika Bauer, Daniel Peterlik, Peter J Flor

Genes Brain Behav· January 2020

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Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis.
Dominik Langgartner, Daniel Peterlik, Sandra Foertsch, Andrea M Füchsl, Petra Brokmann, Peter J Flor

Brain Behav Immun· August 2017

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Pharmacological modulation of metabotropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependent manner.
David A Slattery, Inga D Neumann, Peter J Flor, Iulia Zoicas

Behav Brain Res· June 2017

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Relief from detrimental consequences of chronic psychosocial stress in mice deficient for the metabotropic glutamate receptor subtype 7.
Daniel Peterlik, Christina Stangl, Anna Bludau, Dominik Grabski, Robert Strasser, Peter J Flor

Neuropharmacology· March 2017

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Type-7 metabotropic glutamate receptors negatively regulate α-adrenergic receptor signalling.
Luisa Iacovelli, Luisa Di Menna, Daniel Peterlik, Christina Stangl, Rosamaria Orlando, Peter J Flor

Neuropharmacology· February 2017

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The Emerging Role of Metabotropic Glutamate Receptors in the Pathophysiology of Chronic Stress-Related Disorders.
Daniel Peterlik, Peter J Flor, Nicole Uschold-Schmidt

Curr Neuropharmacol· January 2017

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Blocking metabotropic glutamate receptor subtype 5 relieves maladaptive chronic stress consequences.
Daniel Peterlik, Christina Stangl, Amelie Bauer, Anna Bludau, Jana Keller, Peter J Flor

Brain Behav Immun· January 2017

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Metabotropic Glutamate Receptor Subtype 7 in the Bed Nucleus of the Stria Terminalis is Essential for Intermale Aggression.
Miwako Masugi-Tokita, Peter J Flor, Mitsuhiro Kawata

Neuropsychopharmacology· February 2016

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AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization.
Ivo Vranesic, Silvio Ofner, Peter Josef Flor, Graeme Bilbe, Rochdi Bouhelal

Bioorg Med Chem· November 2014

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Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior.
Christine E Gee, Daniel Peterlik, Christoph Neuhäuser, Rochdi Bouhelal, Klemens Kaupmann, Peter J Flor

J Biol Chem· April 2014

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Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse.
Richard M O'Connor, Deepak R Thakker, Markus Schmutz, Herman van der Putten, Daniel Hoyer, Peter J Flor

Neuropharmacology· September 2013

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Differential roles of mGlu(7) and mGlu(8) in amygdala-dependent behavior and physiology.
Markus Fendt, Stefan Imobersteg, Daniel Peterlik, Frédérique Chaperon, Catherine Mattes, Peter J Flor

Neuropharmacology· September 2013

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Differential effects of baclofen and oxytocin on the increased ethanol consumption following chronic psychosocial stress in mice.
Sebastian Peters, David A Slattery, Peter J Flor, Inga D Neumann, Stefan O Reber

Addict Biol· January 2013

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Orthosteric versus allosteric GPCR activation: the great challenge of group-III mGluRs.
Peter J Flor, Francine C Acher

Biochem Pharmacol· August 2012

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Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats.
Amine Bahi, Katharina Fizia, Monika Dietz, Fabrizio Gasparini, Peter J Flor

Addict Biol· March 2012

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Pharmacological interference with metabotropic glutamate receptor subtype 7 but not subtype 5 differentially affects within- and between-session extinction of Pavlovian conditioned fear.
Iulia Toth, Monika Dietz, Daniel Peterlik, Sabine E Huber, Markus Fendt, Peter J Flor

Neuropharmacology· March 2012

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Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues.
Marcela Julio-Pieper, Peter J Flor, Timothy G Dinan, John F Cryan

Pharmacol Rev· March 2011

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Metabotropic glutamate receptor 7: at the interface of cognition and emotion.
Richard M O'Connor, Beate C Finger, Peter J Flor, John F Cryan

Eur J Pharmacol· August 2010

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Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission.
Katarzyna Stachowicz, Piotr Brañski, Kinga Kłak, Herman van der Putten, John F Cryan, Peter J Flor

Behav Pharmacol· September 2008

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Amygdaloid metabotropic glutamate receptor subtype 7 is involved in the acquisition of conditioned fear.
Stephanie Siegl, Peter J Flor, Markus Fendt

Neuroreport· July 2008

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Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.
Agnieszka Palucha, Kinga Klak, Piotr Branski, Herman van der Putten, Peter J Flor

Psychopharmacology (Berl)· November 2007

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Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking.
Christina Zeitz, Ursula Forster, John Neidhardt, Silke Feil, Stefan Kälin, Peter J Flor

Hum Mutat· August 2007

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Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first class of 3'-substituted trans C1'-2'-2-(2'-phosphonocyclopropyl)glycines.
Maura Marinozzi, Michaela Serpi, Laura Amori, Monica Gavilan Diaz, Gabriele Costantino, Peter J Flor

Bioorg Med Chem· May 2007

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