Publications by authors named "Peter Karran"

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Mutation and aging: news from the pool.
Francesca Marcon, Margherita Bignami, Peter Karran

Aging (Albany NY)· May 2023

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Young transgenic hMTH1 mice are protected against dietary fat-induced metabolic stress-implications for enhanced longevity.
Francesca Marcon, Roberta Meschini, Egidio Iorio, Simonetta Palleschi, Gabriele De Luca, Peter Karran

Aging Cell· July 2022

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Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA.
Reto Brem, Melisa Guven, Peter Karran

Free Radic Biol Med· June 2017

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Oxidative stress induced by UVA photoactivation of the tryptophan UVB photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) inhibits nucleotide excision repair in human cells.
Reto Brem, Peter Macpherson, Melisa Guven, Peter Karran

Sci Rep· June 2017

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Photosensitized UVA-Induced Cross-Linking between Human DNA Repair and Replication Proteins and DNA Revealed by Proteomic Analysis.
Melisa Guven, Karin Barnouin, Ambrosius P Snijders, Peter Karran

J Proteome Res· December 2016

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Protein oxidation, UVA and human DNA repair.
Peter Karran, Reto Brem

DNA Repair (Amst)· August 2016

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Oxidative Stress-Induced Protein Damage Inhibits DNA Repair and Determines Mutation Risk and Therapeutic Efficacy.
Elizabeth McAdam, Reto Brem, Peter Karran

Mol Cancer Res· July 2016

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Oxidative Damage to RPA Limits the Nucleotide Excision Repair Capacity of Human Cells.
Melisa Guven, Reto Brem, Peter Macpherson, Matthew Peacock, Peter Karran

J Invest Dermatol· November 2015

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MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation.
Francesca Grasso, Vitalba Ruggieri, Gabriele De Luca, Paola Leopardi, Maria Teresa Mancuso, Peter Karran

Oncotarget· April 2015

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UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions.
Reto Brem, Xiaohui Zhang, Yao-Zhong Xu, Peter Karran

J Photochem Photobiol B· April 2015

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DNA repair inhibition by UVA photoactivated fluoroquinolones and vemurafenib.
Matthew Peacock, Reto Brem, Peter Macpherson, Peter Karran

Nucleic Acids Res· December 2014

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Response to Emanuele.
Quentin Gueranger, Feng Li, Matthew Peacock, Annabel Larnicol-Fery, Reto Brem, Peter Karran

J Invest Dermatol· July 2014

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Protein oxidation and DNA repair inhibition by 6-thioguanine and UVA radiation.
Quentin Gueranger, Feng Li, Matthew Peacock, Annabel Larnicol-Fery, Reto Brem, Peter Karran

J Invest Dermatol· May 2014

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Efficient long DNA gap-filling in a mammalian cell-free system: a potential new in vitro DNA replication assay.
Seiki Nakao, Sufang Zhang, Markku Vaara, Juhani E Syväoja, Marietta Y Lee, Peter Karran

Biochimie· February 2013

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Oxidation-mediated DNA cross-linking contributes to the toxicity of 6-thioguanine in human cells.
Reto Brem, Peter Karran

Cancer Res· September 2012

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Multiple forms of DNA damage caused by UVA photoactivation of DNA 6-thioguanine.
Reto Brem, Peter Karran

Photochem Photobiol· April 2012

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UVA photosensitization of thiopurines and skin cancer in organ transplant recipients.
Natalie R Attard, Peter Karran

Photochem Photobiol Sci· January 2012

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4-Thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy.
Olivier Reelfs, Peter Karran, Antony R Young

Photochem Photobiol Sci· January 2012

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Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells.
Olivier Reelfs, Peter Macpherson, Xiaolin Ren, Yao-Zhong Xu, Peter Karran

Nucleic Acids Res· December 2011

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6-Thioguanine damages mitochondrial DNA and causes mitochondrial dysfunction in human cells.
Ilse Daehn, Reto Brem, Eva Barkauskaite, Peter Karran

FEBS Lett· December 2011

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Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation.
Reto Brem, Ilse Daehn, Peter Karran

DNA Repair (Amst)· August 2011

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Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA.
Quentin Gueranger, Azadeh Kia, David Frith, Peter Karran

Nucleic Acids Res· July 2011

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Photo-oxidation of 6-thioguanine by UVA: the formation of addition products with low molecular weight thiol compounds.
Xiaolin Ren, Yao-Zhong Xu, Peter Karran

Photochem Photobiol· March 2011

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Carcinogenic mechanisms related to immunosuppressive therapy.
Conal M Perrett, Catherine A Harwood, Jane M McGregor, Peter Karran

Cancer Treat Res· September 2010

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Guanine sulphinate is a major stable product of photochemical oxidation of DNA 6-thioguanine by UVA irradiation.
Xiaolin Ren, Feng Li, Graham Jeffs, Xiaohong Zhang, Yao-Zhong Xu, Peter Karran

Nucleic Acids Res· April 2010

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