Publications by authors named "Peter Keizer"

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A Comparative Analysis of Grip Strength Evaluation Methods in a Large Cohort of Aged Mice.
Giorgia Bigossi, Serena Marcozzi, Maria Elisa Giuliani, Giovanni Lai, Beatrice Bartozzi, Peter L J de Keizer

J Cachexia Sarcopenia Muscle· October 2025

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A Novel Cognitive Frailty Index for Geriatric Mice.
Serena Marcozzi, Giorgia Bigossi, Maria Elisa Giuliani, Giovanni Lai, Beatrice Bartozzi, Peter L J de Keizer

Aging Cell· July 2025

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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.
Benjamin Bourgeois, Emil Spreitzer, Daniel Platero-Rochart, Margret Paar, Qishun Zhou, Peter L J de Keizer

Nat Commun· July 2025

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Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options.
Ilja Boone, Evelyn Houtman, Margo Tuerlings, Jim J van den Berg, Johannes Lehmann, Peter L J de Keizer

J Orthop Res· May 2025

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Are immunosenescent T cells really senescent?
Helena Slaets, Naomi Veeningen, Peter L J de Keizer, Niels Hellings, Sven Hendrix

Aging Cell· October 2024

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Identified senescence endotypes in aged cartilage are reflected in the blood metabolome.
Ilja Boone, Margo Tuerlings, Rodrigo Coutinho de Almeida, Johannes Lehmann, Yolande Ramos, Peter de Keizer

Geroscience· April 2024

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Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.
Rebeca Uceda-Castro, Andreia S Margarido, Lesley Cornet, Serena Vegna, Kerstin Hahn, Peter L J de Keizer

Cell Rep Med· November 2022

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WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion.
Johannes Lehmann, Roberto Narcisi, Natasja Franceschini, Danai Chatzivasileiou, Cindy G Boer, Peter L J de Keizer

Cell Mol Life Sci· January 2022

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Residual Disease in Glioma Recurrence: A Dangerous Liaison with Senescence.
Diana A Putavet, Peter L J de Keizer

Cancers (Basel)· March 2021

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ARDD 2020: from aging mechanisms to interventions.
Garik V Mkrtchyan, Kotb Abdelmohsen, Pénélope Andreux, Ieva Bagdonaite, Nir Barzilai, Peter de Keizer

Aging (Albany NY)· December 2020

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Senescent Cells Drive Frailty through Systemic Signals.
Johannes Lehmann, Marjolein P Baar, Peter L J de Keizer

Trends Mol Med· November 2018

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Musculoskeletal senescence: a moving target ready to be eliminated.
Marjolein P Baar, Eusebio Perdiguero, Pura Muñoz-Cánoves, Peter Lj de Keizer

Curr Opin Pharmacol· June 2018

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Cellular senescence as a therapeutic target to improve renal transplantation outcome.
Hester van Willigenburg, Peter L J de Keizer, Ron W F de Bruin

Pharmacol Res· April 2018

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Maintenance and repair of an aging life cycle.
Marjolein P Baar, Hester Van Willigenburg, Peter L J de Keizer

Oncotarget· October 2017

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The Fountain of Youth by Targeting Senescent Cells?
Peter L J de Keizer

Trends Mol Med· January 2017

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Pin1-FOXM1 inhibitors: a potential therapeutic for metastatic melanoma?
Peter Lj de Keizer

Melanoma Manag· September 2016

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Rapidly progressive Kaposi's Sarcoma in an Iraqi boy received Valproic acid: a case report and review of literature.
Lika'a Fasih Y Al-Kzayer, Peter Keizer, Farah T Abdulraheem, Kenji Sano, Minoru Kamata

BMC Pediatr· July 2016

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'Inverted' analogs of the antibiotic gramicidin S with an improved biological profile.
Varsha V Kapoerchan, Annemiek D Knijnenburg, Peter Keizer, Emile Spalburg, Albert J de Neeling

Bioorg Med Chem· October 2012

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Glucocorticoids suppress selected components of the senescence-associated secretory phenotype.
Remi-Martin Laberge, Lili Zhou, Melissa R Sarantos, Francis Rodier, Adam Freund, Peter L J de Keizer

Aging Cell· August 2012

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Forkhead box o as a sensor, mediator, and regulator of redox signaling.
Peter L J de Keizer, Boudewijn M T Burgering, Tobias B Dansen

Antioxid Redox Signal· March 2011

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The DNA damage repair protein Ku70 interacts with FOXO4 to coordinate a conserved cellular stress response.
Arjan B Brenkman, Niels J F van den Broek, Peter L J de Keizer, Dik C van Gent, Boudewijn M T Burgering

FASEB J· November 2010

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Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence.
Peter L J de Keizer, Leisl M Packer, Anna A Szypowska, Paulien E Riedl-Polderman, Niels J F van den Broek

Cancer Res· November 2010

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p53: Pro-aging or pro-longevity?
Peter L J de Keizer, Rémi-Martin Laberge, Judith Campisi

Aging (Albany NY)· July 2010

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Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity.
Tobias B Dansen, Lydia M M Smits, Miranda H van Triest, Peter L J de Keizer, Dik van Leenen

Nat Chem Biol· September 2009

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