Publications by authors named "Peter O Fedichev"

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Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit.
Timothy V Pyrkov, Konstantin Avchaciov, Andrei E Tarkhov, Leonid I Menshikov, Andrei V Gudkov, Peter O Fedichev

Nat Commun· May 2021

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AI-Driven Identification of Exceptionally Efficacious Polypharmacological Compounds That Extend the Lifespan of Caenorhabditis elegans.
Konstantin Avchaciov, Khalyd J Clay, Kirill A Denisov, Olga Burmistrova, Michael Petrascheck, Peter O Fedichev

Aging Cell· July 2025

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Challenges and recommendations for the translation of biomarkers of aging.

Nat Aging· October 2024

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Validation of biomarkers of aging.
Mahdi Moqri, Chiara Herzog, Jesse R Poganik, Kejun Ying, Jamie N Justice, Peter O Fedichev

Nat Med· February 2024

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Unsupervised learning of aging principles from longitudinal data.
Konstantin Avchaciov, Marina P Antoch, Ekaterina L Andrianova, Andrei E Tarkhov, Leonid I Menshikov, Peter O Fedichev

Nat Commun· November 2022

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Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis.
Irene Lopez-Fabuel, Marina Garcia-Macia, Costantina Buondelmonte, Olga Burmistrova, Nicolo Bonora, Peter O Fedichev

Nat Commun· January 2022

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Genetic and phenotypic analysis of the causal relationship between aging and COVID-19.
Kejun Ying, Ranran Zhai, Timothy V Pyrkov, Anastasia V Shindyapina, Marco Mariotti, Peter O Fedichev

Commun Med (Lond)· October 2021

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Association between housing type and accelerated biological aging in different sexes: moderating effects of health behaviors.
Ted Kheng Siang Ng, David Bruce Matchar, Timothy V Pyrkov, Peter O Fedichev, Angelique Wei-Ming Chan

Aging (Albany NY)· August 2021

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Deep longitudinal phenotyping of wearable sensor data reveals independent markers of longevity, stress, and resilience.
Timothy V Pyrkov, Ilya S Sokolov, Peter O Fedichev

Aging (Albany NY)· March 2021

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COVID-19 is an emergent disease of aging.
Didac Santesmasses, José Pedro Castro, Aleksandr A Zenin, Anastasia V Shindyapina, Maxim V Gerashchenko, Peter O Fedichev

Aging Cell· October 2020

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Identification of 12 genetic loci associated with human healthspan.
Aleksandr Zenin, Yakov Tsepilov, Sodbo Sharapov, Evgeny Getmantsev, L I Menshikov, Peter O Fedichev

Commun Biol· April 2020

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Germline burden of rare damaging variants negatively affects human healthspan and lifespan.
Anastasia V Shindyapina, Aleksandr A Zenin, Andrei E Tarkhov, Didac Santesmasses, Peter O Fedichev

Elife· April 2020

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Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice.
Olga Burmistrova, Ana Olias-Arjona, Rebeca Lapresa, Daniel Jimenez-Blasco, Tatiana Eremeeva, Peter O Fedichev

Sci Rep· August 2019

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A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories.
Andrei E Tarkhov, Ramani Alla, Srinivas Ayyadevara, Mikhail Pyatnitskiy, Leonid I Menshikov, Peter O Fedichev

Sci Rep· May 2019

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Quantitative characterization of biological age and frailty based on locomotor activity records.
Timothy V Pyrkov, Evgeny Getmantsev, Boris Zhurov, Konstantin Avchaciov, Mikhail Pyatnitskiy, Peter O Fedichev

Aging (Albany NY)· October 2018

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Hacking Aging: A Strategy to Use Big Data From Medical Studies to Extend Human Life.
Peter O Fedichev

Front Genet· October 2018

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Extracting biological age from biomedical data via deep learning: too much of a good thing?
Timothy V Pyrkov, Konstantin Slipensky, Mikhail Barg, Alexey Kondrashin, Boris Zhurov, Peter O Fedichev

Sci Rep· March 2018

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Strehler-Mildvan correlation is a degenerate manifold of Gompertz fit.
Andrei E Tarkhov, Leonid I Menshikov, Peter O Fedichev

J Theor Biol· March 2017

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Structure-based design of small-molecule ligands of phosphofructokinase-2 activating or inhibiting glycolysis.
Timothy V Pyrkov, Irina A Sevostyanova, Elena V Schmalhausen, Andrei N Shkoporov, Andrei A Vinnik, Peter O Fedichev

ChemMedChem· August 2013

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Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions.
Catherine Joce, Joshua A Stahl, Mitesh Shridhar, Mark R Hutchinson, Linda R Watkins, Peter O Fedichev

Bioorg Med Chem Lett· September 2010

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