Publications by authors named "Peter Parsons"

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Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade.
Jason K Cullen, Pei-Yi Yap, Blake Ferguson, Zara C Bruce, Motoko Koyama, Peter G Parsons

J Immunother Cancer· April 2024

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Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds.
Lydia C Powell, Jason K Cullen, Glen M Boyle, Tom De Ridder, Pei-Yi Yap, Peter G Parsons

Sci Transl Med· September 2022

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Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree ().
Giuseppina Chianese, Hawraz Ibrahim M Amin, Chiara Maioli, Paul Reddell, Peter Parsons

J Nat Prod· August 2022

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Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes.
Jason K Cullen, Glen M Boyle, Pei-Yi Yap, Stefan Elmlinger, Jacinta L Simmons, Peter G Parsons

Sci Rep· January 2021

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Synthetic Tigliane Intermediates Engage Thiols to Induce Potent Cell Line Selective Anti-Cancer Activity.
Sharon Chow, Tanja Krainz, Christian J Bettencourt, Natasa Broit, Blake Ferguson, Peter G Parsons

Chemistry· October 2020

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EBC-232 and 323: A Structural Conundrum Necessitating Unification of Five In Silico Prediction and Elucidation Methods.
Lidia A Maslovskaya, Andrei I Savchenko, Elizabeth H Krenske, Sharon Chow, Tina Holt, Peter G Parsons

Chemistry· September 2020

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Potent Antibacterial Prenylated Acetophenones from the Australian Endemic Plant .
Trong D Tran, Malin A Olsson, David J McMillan, Jason K Cullen, Peter G Parsons

Antibiotics (Basel)· August 2020

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Topical treatments for skin cancer.
Jason K Cullen, Jacinta L Simmons, Peter G Parsons, Glen M Boyle

Adv Drug Deliv Rev· January 2020

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Antibacterial 5α-Spirostane Saponins from the Fruit of .
Trong D Tran, Malin A Olsson, Md Abu Choudhury, David J McMillan, Jason K Cullen, Peter G Parsons

J Nat Prod· October 2019

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Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate.
Catherine M E Barnett, Natasa Broit, Pei-Yi Yap, Jason K Cullen, Peter G Parsons

Invest New Drugs· February 2019

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New Casbanes and the First trans-Cyclopropane seco-Casbane from the Australian Rainforest Plant Croton insularis.
Lidiya A Maslovskaya, Andrei I Savchenko, Carly J Pierce, Glen M Boyle, Victoria A Gordon, Peter G Parsons

Chemistry· January 2019

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Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.
Benjamin A Chalmers, Hui Xing, Sevan Houston, Charlotte Clark, Sussan Ghassabian, Peter G Parsons

Angew Chem Int Ed Engl· July 2018

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Furofuran lignans from the Simpson Desert species Eremophila macdonnellii.
Yuen P Tan, Andrei I Savchenko, Natasa Broit, Glen M Boyle, Peter G Parsons

Fitoterapia· April 2018

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The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells.
David Wilson, Glen M Boyle, Lachlan McIntyre, Matthew J Nolan, Peter G Parsons

Toxins (Basel)· October 2017

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The First Casbane Hydroperoxides EBC-304 and EBC-320 from the Australian Rainforest.
Lidiya A Maslovskaya, Andrei I Savchenko, Victoria A Gordon, Paul W Reddell, Carly J Pierce, Peter G Parsons

Chemistry· January 2017

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Expression profiling of cutaneous squamous cell carcinoma with perineural invasion implicates the p53 pathway in the process.
Timothy A Warren, Natasa Broit, Jacinta L Simmons, Carly J Pierce, Sharad Chawla, Peter G Parsons

Sci Rep· September 2016

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Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.
Benjamin A Chalmers, Hui Xing, Sevan Houston, Charlotte Clark, Sussan Ghassabian, Peter G Parsons

Angew Chem Int Ed Engl· March 2016

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Intra-lesional injection of the novel PKC activator EBC-46 rapidly ablates tumors in mouse models.
Glen M Boyle, Marjorie M A D'Souza, Carly J Pierce, Ryan A Adams, Aaron S Cantor, Peter G Parsons

PLoS One· January 2016

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Ectopic expression of protein kinase C-β sensitizes head and neck squamous cell carcinoma to diterpene esters.
Ryan A Adams, Marjorie M A D'Souza, Carly J Pierce, Natasa Korica, Ben Wallwork, Peter G Parsons

Anticancer Res· March 2015

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The value of nature's natural product library for the discovery of New Chemical Entities: the discovery of ingenol mebutate.
Steven M Ogbourne, Peter G Parsons

Fitoterapia· October 2014

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Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324.
Lidiya A Maslovskaya, Andrei I Savchenko, Elizabeth H Krenske, Victoria A Gordon, Paul W Reddell, Peter G Parsons

Chem Commun (Camb)· October 2014

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Unprecedented 1,14-seco-crotofolanes from Croton insularis: oxidative cleavage of crotofolin C by a putative homo-Baeyer-Villiger rearrangement.
Lidiya A Maslovskaya, Andrei I Savchenko, Carly J Pierce, Victoria A Gordon, Paul W Reddell, Peter G Parsons

Chemistry· October 2014

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EBC-219: a new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond.
Lidiya A Maslovskaya, Andrei I Savchenko, Elizabeth H Krenske, Carly J Pierce, Victoria A Gordon, Peter G Parsons

Angew Chem Int Ed Engl· July 2014

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Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo.
Barbara E Rolfe, Idriss Blakey, Oliver Squires, Hui Peng, Nathan R B Boase, Peter G Parsons

J Am Chem Soc· February 2014

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Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment.
Ying Dong, Carson Stephens, Carina Walpole, Joakim E Swedberg, Glen M Boyle, Peter G Parsons

PLoS One· September 2013

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