Publications by authors named "Peter Searson"

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A tissue-engineered endothelial cell - smooth muscle cell arteriole-like model.
Ninghao Zhu, Lily Liang, Nan Zhao, Haosong Chen, Peter C Searson

Biomater Sci· November 2025

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Brain vascular basement membrane: Comparison of human and mouse brain at the transcriptomic and proteomic levels.
Nan Zhao, Alexander F Pessell, Tracy D Chung, Peter C Searson

Matrix Biol· August 2025

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Aged human serum induces vascular changes in an isogenic co-culture venule model.
Tracy D Chung, Raleigh M Linville, Nan Zhao, Linus Wang, Zikai Xia, Peter C Searson

Stem Cell Reports· July 2025

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Extravasation of Borrelia burgdorferi Across the Blood-Brain Barrier is an Extremely Rare Event.
Linus Wang, Zikai Xia, Anjan Singh, Bhavna Murarka, Nicole Baumgarth, Peter C Searson

Adv Sci (Weinh)· May 2025

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Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications.
Nan Zhao, Alexander F Pessell, Ninghao Zhu, Peter C Searson

Adv Healthc Mater· August 2024

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Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice.
Jeremy M Sullivan, Anna M Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Peter C Searson

Sci Transl Med· May 2024

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Disruption of epithelium integrity by inflammation-associated fibroblasts through prostaglandin signaling.
Yi Dong, Blake A Johnson, Linhao Ruan, Maged Zeineldin, Tianhao Bi, Peter Searson

Sci Adv· April 2024

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Corrigendum: The influence of physiological and pathological perturbations on blood-brain barrier function.
Nan Zhao, Tracy D Chung, Zhaobin Guo, John J Jamieson, Lily Liang, Peter C Searson

Front Neurosci· March 2024

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Modeling Substrate Entry into the P-Glycoprotein Efflux Pump at the Blood-Brain Barrier.
Christian Jorgensen, Martin B Ulmschneider, Peter C Searson

J Med Chem· December 2023

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A least-squares-fitting procedure for an efficient preclinical ranking of passive transport across the blood-brain barrier endothelium.
Christian Jorgensen, Evan P Troendle, Jakob P Ulmschneider, Peter C Searson, Martin B Ulmschneider

J Comput Aided Mol Des· November 2023

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A tissue-engineered model of the blood-tumor barrier during metastatic breast cancer.
Raleigh M Linville, Joanna Maressa, Zhaobin Guo, Tracy D Chung, Alanna Farrell, Peter C Searson

Fluids Barriers CNS· November 2023

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The Cancer Moonshot, the role of in vitro models, model accuracy, and the need for validation.
Peter C Searson

Nat Nanotechnol· October 2023

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The influence of physiological and pathological perturbations on blood-brain barrier function.
Nan Zhao, Tracy D Chung, Zhaobin Guo, John J Jamieson, Lily Liang, Peter C Searson

Front Neurosci· October 2023

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Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling: IAFs disrupt colon epithelium via PGE2-EP4.
Yi Dong, Blake A Johnson, Linhao Ruan, Maged Zeineldin, Albert Z Liu, Peter Searson

bioRxiv· September 2023

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Modeling angiogenesis in the human brain in a tissue-engineered post-capillary venule.
Nan Zhao, Sarah Kulkarni, Sophia Zhang, Raleigh M Linville, Tracy D Chung, Peter Searson

Angiogenesis· May 2023

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The feasibility of remotely monitoring physical, cognitive, and psychosocial function in individuals with stroke or chronic obstructive pulmonary disease.
Margaret A French, Eva Keatley, Junyao Li, Aparna Balasubramanian, Nadia N Hansel, Peter Searson

Digit Health· May 2023

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Visualization of the Dynamics of Invasion and Intravasation of the Bacterium That Causes Lyme Disease in a Tissue Engineered Dermal Microvessel Model.
Zhaobin Guo, Nan Zhao, Tracy D Chung, Anjan Singh, Ikshu Pandey, Peter C Searson

Adv Sci (Weinh)· December 2022

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Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood-brain barrier microvessels.
Raleigh M Linville, Matthew B Sklar, Gabrielle N Grifno, Renée F Nerenberg, Justin Zhou, Peter C Searson

Fluids Barriers CNS· November 2022

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Evaluation of physical health status beyond daily step count using a wearable activity sensor.
Zheng Xu, Nicole Zahradka, Seyvonne Ip, Amir Koneshloo, Ryan T Roemmich, Peter C Searson

NPJ Digit Med· November 2022

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Precision Rehabilitation: Optimizing Function, Adding Value to Health Care.
R James Cotton, Richard L Segal Rick, Bryant A Seamon, Amrita Sahu, Michelle M McLeod, Peter Searson

Arch Phys Med Rehabil· September 2022

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Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity.
David Pamies, Daphne Wiersma, Moriah E Katt, Liang Zhao, Johannes Burtscher, Peter C Searson

Neurobiol Dis· July 2022

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Engineering the human blood-brain barrier at the capillary scale using a double-templating technique.
Nan Zhao, Zhaobin Guo, Sarah Kulkarni, Danielle Norman, Sophia Zhang, Peter Searson

Adv Funct Mater· July 2022

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Brain microvascular endothelial cell dysfunction in an isogenic juvenile iPSC model of Huntington's disease.
Raleigh M Linville, Renée F Nerenberg, Gabrielle Grifno, Diego Arevalo, Zhaobin Guo, Peter C Searson

Fluids Barriers CNS· June 2022

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Hypoxia-induced blood-brain barrier dysfunction is prevented by pericyte-conditioned media via attenuated actomyosin contractility and claudin-5 stabilization.
John J Jamieson, YingYu Lin, Nicholas Malloy, Daniel Soto, Peter C Searson

FASEB J· May 2022

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Effects of acute and chronic oxidative stress on the blood-brain barrier in 2D and 3D in vitro models.
Tracy D Chung, Raleigh M Linville, Zhaobin Guo, Robert Ye, Ria Jha, Peter C Searson

Fluids Barriers CNS· May 2022

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