Publications by authors named "Peter Strack"

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Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.
Bryan Severyn, Thi Nguyen, Michael D Altman, Lixia Li, Kumiko Nagashima, Peter Strack

J Biomol Screen· October 2016

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Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression.
Peter J Stivers, Lauren Harmonay, Alexandra Hicks, Huseyin Mehmet, Melody Morris, Peter R Strack

PLoS One· June 2016

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Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models.
Chaoxin Hu, Tikva Dadon, Venugopal Chenna, Shinichi Yabuuchi, Rajat Bannerji, Peter Strack

Mol Cancer Ther· July 2015

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MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis.
Robert N Booher, Harold Hatch, Brian M Dolinski, Thi Nguyen, Lauren Harmonay, Peter Strack

PLoS One· June 2015

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Evaluating TBK1 as a therapeutic target in cancers with activated IRF3.
Asli Muvaffak, Qi Pan, Haiyan Yan, Rafael Fernandez, Jongwon Lim, Peter Strack

Mol Cancer Res· July 2014

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A zinc finger nuclease assay to rapidly quantitate homologous recombination proficiency in human cell lines.
Jing Yuan, Peter R Strack, Carlo Toniatti, Marc Pelletier

Anal Biochem· March 2013

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Level of phosphohistone H3 among various types of human cancers.
Amy Sun, Wei Zhou, Jared Lunceford, Peter Strack, Lisa M Dauffenbach

BMJ Open· October 2012

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Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.
Peter Grudzien, Shelly Lo, Kathy S Albain, Patricia Robinson, Prabha Rajan, Peter R Strack

Anticancer Res· October 2010

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Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres.
Jie Chen, Santosh Kesari, Christine Rooney, Peter R Strack, Jihua Chen

Genes Cancer· August 2010

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Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia.
Takaomi Sanda, Xiaoyu Li, Alejandro Gutierrez, Yebin Ahn, Donna S Neuberg, Peter R Strack

Blood· March 2010

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Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
Clay L Efferson, Christopher T Winkelmann, Christopher Ware, Timothy Sullivan, Saverio Giampaoli, Peter R Strack

Cancer Res· March 2010

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Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
Sudhir S Rao, Jennifer O'Neil, Cole D Liberator, James S Hardwick, Xudong Dai, Peter R Strack

Cancer Res· April 2009

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Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway.
Irene Graziani, Sandra Eliasz, Melissa A De Marco, Yuanbin Chen, Harvey I Pass, Peter R Strack

Cancer Res· December 2008

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Control of cell growth and survival by enzymes of the fatty acid synthesis pathway in HCT-116 colon cancer cells.
Yanai Zhan, Nicole Ginanni, Michael R Tota, Margaret Wu, Nathan W Bays, Peter R Strack

Clin Cancer Res· September 2008

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Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung.
Yuanbin Chen, Melissa A De Marco, Irene Graziani, Adi F Gazdar, Peter R Strack

Cancer Res· September 2007

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FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts

J Exp Med· August 2007

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Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.
Huw D Lewis, Matthew Leveridge, Peter R Strack, Christine D Haldon, Jennifer O'neil

Chem Biol· February 2007

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3-Aryl-4-hydroxyquinolin-2(1H)-one derivatives as type I fatty acid synthase inhibitors.
Alexey Rivkin, Yoona R Kim, Mark T Goulet, Nathan Bays, Armetta D Hill, Peter R Strack

Bioorg Med Chem Lett· September 2006

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Valosin-containing protein phosphorylation at Ser784 in response to DNA damage.
Mark Livingstone, Hong Ruan, Jessica Weiner, Karl R Clauser, Peter Strack

Cancer Res· September 2005

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Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors.
Zhihong Lai, Tao Yang, Young B Kim, Thais M Sielecki, Melody A Diamond, Peter Strack

Proc Natl Acad Sci U S A· November 2002

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