Publications by authors named "Peter Wermuth"

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Effects of Oxygen Manipulation on Myofibroblast Phenotypic Transformation in Patients With Radiation-Induced Fibrosis.
Eric V Mastrolonardo, Sarah Sussman, Bo Yun, Victor Jegede, Dev R Amin, Peter J Wermuth

Wound Repair Regen· September 2025

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Mechanisms of extracellular vesicle uptake and implications for the design of cancer therapeutics.
Stephanie R Jackson Cullison, Joseph P Flemming, Kubra Karagoz, Peter J Wermuth, Mỹ G Mahoney

J Extracell Biol· November 2024

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Extracellular Vesicles in the Skin Microenvironment: Emerging Roles as Biomarkers and Therapeutic Tools in Dermatologic Health and Disease.
Joseph P Flemming, Peter J Wermuth, Mỹ G Mahoney

J Invest Dermatol· February 2024

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Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis.
Morgan D Basta, Svetlana Petruk, Ross Summer, Joel Rosenbloom, Peter J Wermuth

iScience· May 2023

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Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases.
Edward J Macarak, Peter J Wermuth, Joel Rosenbloom, Jouni Uitto

Exp Dermatol· January 2021

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Chemical exposure-induced systemic fibrosing disorders: Novel insights into systemic sclerosis etiology and pathogenesis.
Sonsoles Piera-Velazquez, Peter J Wermuth, Juan J Gomez-Reino, John Varga, Sergio A Jimenez

Semin Arthritis Rheum· December 2020

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Molecular characteristics and functional differences of anti-PM/Scl autoantibodies and two other distinct and unique supramolecular structures known as "EXOSOMES".
Peter J Wermuth, Sergio A Jimenez

Autoimmun Rev· October 2020

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miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas.
Joseph P Flemming, Brianna L Hill, Mohammed W Haque, Jessica Raad, Claudine S Bonder, Peter J Wermuth

J Extracell Vesicles· July 2020

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Abrogation of transforming growth factor-β-induced tissue fibrosis in mice with a global genetic deletion of Nox4.
Peter J Wermuth, Fabian A Mendoza, Sergio A Jimenez

Lab Invest· April 2019

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Identification of novel systemic sclerosis biomarkers employing aptamer proteomic analysis.
Peter J Wermuth, Sonsoles Piera-Velazquez, Sergio A Jimenez

Rheumatology (Oxford)· October 2018

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Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib).
Peter J Wermuth, Sergio A Jimenez

PLoS One· August 2018

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Existing and novel biomarkers for precision medicine in systemic sclerosis.
Peter J Wermuth, Sonsoles Piera-Velazquez, Joel Rosenbloom, Sergio A Jimenez

Nat Rev Rheumatol· July 2018

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Trametinib prevents mesothelial-mesenchymal transition and ameliorates abdominal adhesion formation.
Edward J Macarak, Christine E Lotto, Deepika Koganti, Xiaoling Jin, Peter J Wermuth

J Surg Res· July 2018

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Exosomes isolated from serum of systemic sclerosis patients display alterations in their content of profibrotic and antifibrotic microRNA and induce a profibrotic phenotype in cultured normal dermal fibroblasts.
Peter J Wermuth, Sonsoles Piera-Velazquez, Sergio A Jimenez

Clin Exp Rheumatol· December 2017

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Desmoglein 2 modulates extracellular vesicle release from squamous cell carcinoma keratinocytes.
Andrew M Overmiller, Jennifer A Pierluissi, Peter J Wermuth, Sami Sauma, Ubaldo Martinez-Outschoorn

FASEB J· August 2017

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Stimulation of Transforming Growth Factor-β1-Induced Endothelial-To-Mesenchymal Transition and Tissue Fibrosis by Endothelin-1 (ET-1): A Novel Profibrotic Effect of ET-1.
Peter J Wermuth, Zhaodong Li, Fabian A Mendoza, Sergio A Jimenez

PLoS One· July 2017

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Endothelial cell-specific activation of transforming growth factor-β signaling in mice induces cutaneous, visceral, and microvascular fibrosis.
Peter J Wermuth, Kellan R Carney, Fabian A Mendoza, Sonsoles Piera-Velazquez, Sergio A Jimenez

Lab Invest· July 2017

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The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases.
Peter J Wermuth, Sergio A Jimenez

Clin Transl Med· April 2015

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Prevalence of mental disorders among detained asylum seekers in deportation arrest in Switzerland and validation of the Brief Jail Mental Health Screen BJMHS.
Marc Graf, Peter Wermuth, Dieter Häfeli, Andreas Weisert, Shuja Reagu

Int J Law Psychiatry· February 2014

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Caveolin-1 deficiency induces spontaneous endothelial-to-mesenchymal transition in murine pulmonary endothelial cells in vitro.
Zhaodong Li, Peter J Wermuth, Bryan S Benn, Michael P Lisanti, Sergio A Jimenez

Am J Pathol· February 2013

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Gadolinium compounds signaling through TLR4 and TLR7 in normal human macrophages: establishment of a proinflammatory phenotype and implications for the pathogenesis of nephrogenic systemic fibrosis.
Peter J Wermuth, Sergio A Jimenez

J Immunol· July 2012

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Effect of protein kinase C delta (PKC-δ) inhibition on the transcriptome of normal and systemic sclerosis human dermal fibroblasts in vitro.
Peter J Wermuth, Sankar Addya, Sergio A Jimenez

PLoS One· April 2012

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Persistent activation of dermal fibroblasts from patients with gadolinium-associated nephrogenic systemic fibrosis.
Sonsoles Piera-Velazquez, Natalia Louneva, Jolanta Fertala, Peter J Wermuth, Francesco Del Galdo

Ann Rheum Dis· November 2010

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NFκB activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of nephrogenic systemic fibrosis.
Francesco Del Galdo, Peter J Wermuth, Sankar Addya, Paolo Fortina, Sergio A Jimenez

Ann Rheum Dis· November 2010

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Induction of the expression of profibrotic cytokines and growth factors in normal human peripheral blood monocytes by gadolinium contrast agents.
Peter J Wermuth, Francesco Del Galdo, Sergio A Jiménez

Arthritis Rheum· May 2009

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