Publications by authors named "Philip Cole"

Claim this Profile
H
Hydantion indolinones as AANAT inhibitors.
Nicole Wandrey, Jake Boley, Dirce Gómez-Galicia, Mackinzi Hill, Mason Bach, Philip A Cole

Bioorg Med Chem Lett· February 2026

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CoREST complex inhibition alters RNA splicing to promote neoantigen expression and enhance tumor immunity.
Robert J Fisher, Kihyun Park, Kwangwoon Lee, Katarina Pinjusic, Allison Vanasse, Philip A Cole

JCI Insight· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DNA bendability regulates transcription factor binding to nucleosomes.
Luca Mariani, Xiao Liu, Kwangwoon Lee, Stephen S Gisselbrecht, Philip A Cole

Nat Struct Mol Biol· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2.
Martin S Taylor, Maggie Chen, Matthew Hancock, Maximilian Wranik, Bryant D Miller, Philip A Cole

Science· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Allosteric Regulator Inositol Phosphate Dramatically Affects the Efficacy and Selectivity of Inhibitors for Different HDAC Complexes.
Wiktoria A Pytel, Urvashi Patel, Joshua P Smalley, Christopher J Millard, Edward A Brown, Philip A Cole

J Am Chem Soc· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML.
Mina M Tayari, Helena Gomes Dos Santos, Sadat Dokaneheifard, Samuel D Whedon, Monica Valencia, Philip A Cole

bioRxiv· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of a BCOR internal tandem duplication in mouse embryonic stem cell to neuronal precursor differentiation.
Zuzer Dhoondia, Hyuckjoon Kang, Kwangwoon Lee, Philip A Cole, Mitzi I Kuroda

Genetics· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biochemical analysis of PD-L1 ubiquitination by CRL3, ARIH1, and NEDD4 family ubiquitin ligases.
Guojiao Xie, Lin Gao, Renee Lu, Linxia Tian, Tiantian Zheng, Philip A Cole

Structure· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biochemistry and regulation of histone lysine L-lactylation.
Xinlei Sheng, Hening Lin, Philip A Cole, Yingming Zhao

Nat Rev Mol Cell Biol· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting NEDD9-SH3 with a Covalent Peptide Controls Endothelial Phenotype.
Andriy O Samokhin, Hyuk-Soo Seo, Alison Leed, Behnoush Hajian, Gregory H Bird, Philip A Cole

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural and enzymatic plasticity of SIRT6 deacylase activity.
Zhipeng A Wang, Jonathan Markert, Samuel D Whedon, Maheeshi Yapa Abeywardana, Xinlei Sheng, Philip A Cole

J Biol Chem· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN.
Reina Iwase, Isabella Jaen Maisonet, Kwangwoon Lee, Sara J Buhrlage, Philip A Cole

Bioorg Chem· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutant protein chemical rescue: From mechanisms to therapeutics.
Timothy R O'Meara, Brad A Palanski, Maggie Chen, Yingfeng Qiao, Philip A Cole

J Biol Chem· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.
Megan J R Yeo, Olivia Zhang, Xiaowen Xie, Eunju Nam, N Connor Payne, Philip A Cole

Nature· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations.
Xiaowen Xie, Olivia Zhang, Megan J R Yeo, Ceejay Lee, Ran Tao, Philip A Cole

Nature· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The CoREST complex is a therapeutic vulnerability in malignant peripheral nerve sheath tumors.
Imad Soukar, Robert J Fisher, Sanjana Bhagavatula, Marianne Collard, Philip A Cole

Sci Rep· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting lysine acetylation readers and writers.
Ming-Ming Zhou, Philip A Cole

Nat Rev Drug Discov· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis.
Ruilong Liu, Xuelian Ren, Yae Eun Park, Huixu Feng, Xinlei Sheng, Philip A Cole

Cell Metab· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance.
Nina Kozlova, Kayla A Cruz, Hanna M Doh, Antoine A Ruzette, Nicholas A Willis, Philip A Cole

bioRxiv· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Circular Engineered Sortase for Interrogating Histone H3 in Chromatin.
Samuel D Whedon, Kwangwoon Lee, Zhipeng A Wang, Emily Zahn, Congcong Lu, Philip A Cole

J Am Chem Soc· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CoREST Complex Inhibition Alters RNA Splicing to Promote Neoantigen Expression and Enhance Tumor Immunity.
Robert J Fisher, Kihyun Park, Kwangwoon Lee, Katarina Pinjusic, Allison Vanasse, Philip A Cole

bioRxiv· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The CoREST complex inhibitor, corin, leads to decreased tumor growth, increased cellular differentiation and extended lifespan in atypical teratoid rhabdoid tumor xenograft models.
Anupa Geethadevi, Nikhil Vaidya, Robert J Fisher, Tyler Findlay, Yiming Deng, Philip A Cole

bioRxiv· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
AANAT kinetics of CoASH-targeted electrophiles of tryptamine and related analogs.
Nicole Wandrey, Luke Hamilton, Jake Boley, Alexis Haynes, Makenna Redinger, Philip A Cole

Bioorg Med Chem Lett· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A circular engineered sortase for interrogating histone H3 in chromatin.
Samuel D Whedon, Kwangwoon Lee, Zhipeng A Wang, Emily Zahn, Congcong Lu, Philip A Cole

bioRxiv· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DNA flexibility regulates transcription factor binding to nucleosomes.
Luca Mariani, Xiao Liu, Kwangwoon Lee, Stephen S Gisselbrecht, Philip A Cole

bioRxiv· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis