Publications by authors named "Samuel D Whedon"

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Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML.
Mina M Tayari, Helena Gomes Dos Santos, Sadat Dokaneheifard, Samuel D Whedon, Monica Valencia

bioRxiv· October 2025

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Structural and enzymatic plasticity of SIRT6 deacylase activity.
Zhipeng A Wang, Jonathan Markert, Samuel D Whedon, Maheeshi Yapa Abeywardana, Xinlei Sheng

J Biol Chem· May 2025

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Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1.
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Samuel D Whedon

Nat Chem Biol· February 2025

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Circular Engineered Sortase for Interrogating Histone H3 in Chromatin.
Samuel D Whedon, Kwangwoon Lee, Zhipeng A Wang, Emily Zahn, Congcong Lu

J Am Chem Soc· December 2024

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Multifaceted regulation of sirtuin 2 (Sirt2) deacetylase activity.
Maheeshi Yapa Abeywardana, Samuel D Whedon, Kwangwoon Lee, Eunju Nam, Rafael Dovarganes

J Biol Chem· September 2024

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A circular engineered sortase for interrogating histone H3 in chromatin.
Samuel D Whedon, Kwangwoon Lee, Zhipeng A Wang, Emily Zahn, Congcong Lu

bioRxiv· September 2024

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A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes.
Anne E Smolko, Daniel W Sullivan, Sarah Naomi Olsen, Hyuckjoon Kang, Samuel D Whedon

Proc Natl Acad Sci U S A· June 2024

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Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination.
Reina Iwase, Daniel R Dempsey, Samuel D Whedon, Hanjie Jiang, Brad A Palanski

J Am Chem Soc· March 2023

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Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation.
Zhipeng A Wang, Jonathan W Markert, Samuel D Whedon, Maheeshi Yapa Abeywardana, Kwangwoon Lee

J Am Chem Soc· March 2023

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KATs off: Biomedical insights from lysine acetyltransferase inhibitors.
Samuel D Whedon, Philip A Cole

Curr Opin Chem Biol· February 2023

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Distinct biochemical properties of the class I histone deacetylase complexes.
Kwangwoon Lee, Samuel D Whedon, Zhipeng A Wang, Philip A Cole

Curr Opin Chem Biol· October 2022

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Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase.
Zhipeng A Wang, Samuel D Whedon, Mingxuan Wu, Siyu Wang, Edward A Brown

J Am Chem Soc· March 2022

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Trimethylation of the R5 Silica-Precipitating Peptide Increases Silica Particle Size by Redirecting Orthosilicate Binding.
Erika L Buckle, Janani Sampath, Nina Michael, Samuel D Whedon, Calvin J A Leonen

Chembiochem· November 2020

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A clickable glutamine (CliQ) derivative for the traceless reversible modification of peptides and proteins.
Samuel D Whedon, Marissa K Parker, Elizabeth L Tyson, Tobias Ritterhoff, Patrick M M Shelton

Chem Commun (Camb)· February 2019

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Biological consequences of improving the structural stability of hairpins that have antimicrobial activity.
Kalkena Sivanesam, Brandon L Kier, Samuel D Whedon, Champak Chatterjee, Niels H Andersen

J Pept Sci· December 2017

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Hairpin structure stability plays a role in the activity of two antimicrobial peptides.
Kalkena Sivanesam, Brandon L Kier, Samuel D Whedon, Champak Chatterjee, Niels H Andersen

FEBS Lett· December 2016

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Selenocysteine as a Latent Bioorthogonal Electrophilic Probe for Deubiquitylating Enzymes.
Samuel D Whedon, Nagula Markandeya, Ambar S J B Rana, Nicholas A Senger, Caroline E Weller

J Am Chem Soc· October 2016

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Aromatic thiol-mediated cleavage of N-O bonds enables chemical ubiquitylation of folded proteins.
Caroline E Weller, Abhinav Dhall, Feizhi Ding, Edlaine Linares, Samuel D Whedon

Nat Commun· September 2016

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A time-resolved Förster resonance energy transfer assay to measure activity of the deamidase of the prokaryotic ubiquitin-like protein.
Ian C Eustis, Jessica Huang, Meagan E Pilkerton, Samuel D Whedon, Champak Chatterjee

Anal Biochem· October 2015

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