Publications by authors named "Philip D Charles"

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Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution.
Nikolas A Baya, Ilknur Sur Erdem, Samvida S Venkatesh, Saskia Reibe, Philip D Charles

Am J Hum Genet· October 2025

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The Developmental Environment Mediates Adult Seminal Proteome Allocation in Male Drosophila melanogaster.
Rebecca von Hellfeld, Rebecca Konietzny, Philip D Charles, Roman Fischer, Benedikt M Kessler

Mol Ecol· October 2025

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Scalable Deep Learning of Histology Images Reveals Genetic and Phenotypic Determinants of Adipocyte Hypertrophy.
Emil Jørsboe, Phil Kubitz, Julius Honecker, Andrea Flaccus, Dagmar Mvondo, Philip D Charles

medRxiv· September 2025

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TDP-43 pathology is associated with divergent protein profiles in ALS brain and spinal cord.
Emily Feneberg, Alexander G Thompson, Philip D Charles, Iolanda Vendrell, Benedikt M Kessler

Acta Neuropathol Commun· August 2025

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Omics Analyses Uncover Host Networks Defining Virus-Permissive and -Hostile Cellular States.
Honglin Chen, Philip D Charles, Quan Gu, Sabrina Liberatori, David L Robertson

Mol Cell Proteomics· May 2025

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Integrative proximal-ubiquitomics profiling for deubiquitinase substrate discovery applied to USP30.
Andreas Damianou, Hannah B L Jones, Athina Grigoriou, Mohammed A Akbor, Edward Jenkins, Philip D Charles

Cell Chem Biol· May 2025

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Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution.
Nikolas A Baya, Ilknur Sur Erdem, Samvida S Venkatesh, Saskia Reibe, Philip D Charles

medRxiv· March 2025

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A novel method to quantify fibrin-fibrin and fibrin-α-antiplasmin cross-links in thrombi formed from human trauma patient plasma.
Gael B Morrow, Sarah Flannery, Philip D Charles, Raphael Heilig, Timea Feller

J Thromb Haemost· June 2024

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Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation.
Thamali Ayagama, Philip D Charles, Samuel J Bose, Barry Boland, David A Priestman

iScience· June 2024

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High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response.
Yuxin Mi, Katie L Burnham, Philip D Charles, Raphael Heilig, Iolanda Vendrell, Charles J Hinds

Sci Transl Med· June 2024

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Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex.
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Philip D Charles

Life Sci Alliance· May 2024

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Stimulating and toxic effect of chromium on growth and photosynthesis of a marine chlorophyte.
Qiong Zhang, Philip D Charles, El Mahdi Bendif, Svenja S Hester, Shabaz Mohammad

New Phytol· January 2024

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Perfusate Proteomes Provide Biological Insight Into Oxygenated Versus Standard Hypothermic Machine Perfusion in Kidney Transplantation.
John F Mulvey, Sadr Ul Shaheed, Philip D Charles, Corinna Snashall, Maria Letizia Lo Faro

Ann Surg· November 2023

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Deep topographic proteomics of a human brain tumour.
Simon Davis, Connor Scott, Janina Oetjen, Philip D Charles, Benedikt M Kessler

Nat Commun· November 2023

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FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.
Ioanna A Rota, Adam E Handel, Stefano Maio, Fabian Klein, Fatima Dhalla, Philip D Charles

Sci Adv· December 2021

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Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP.
Emily Feneberg, Philip D Charles, Mattéa J Finelli, Connor Scott, Benedikt M Kessler

Brain Pathol· July 2021

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A comparative evaluation of telehealth and direct assessment when screening for spasticity in residents of two long-term care facilities.
Kelly A Harper, Emily C Butler, Mallory L Hacker, Aaditi Naik, Bryan R Eoff, Philip David Charles

Clin Rehabil· April 2021

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Network Analysis of the CSF Proteome Characterizes Convergent Pathways of Cellular Dysfunction in ALS.
Alexander G Thompson, Elizabeth Gray, Philip D Charles, Michele T M Hu, Kevin Talbot

Front Neurosci· March 2021

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Sex Peptide controls the assembly of lipid microcarriers in seminal fluid.
S Mark Wainwright, Ben R Hopkins, Cláudia C Mendes, Aashika Sekar, Benjamin Kroeger, Philip D Charles

Proc Natl Acad Sci U S A· February 2021

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An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.
Emily Feneberg, David Gordon, Alexander G Thompson, Mattéa J Finelli, Ruxandra Dafinca, Philip D Charles

Neurobiol Dis· October 2020

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CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis.
Alexander G Thompson, Elizabeth Gray, Imre Mäger, Marie-Laëtitia Thézénas, Philip D Charles

Clin Proteomics· August 2020

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Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable in .
Irem Sepil, Ben R Hopkins, Rebecca Dean, Eleanor Bath, Solomon Friedman, Philip D Charles

Proc Natl Acad Sci U S A· July 2020

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Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.
Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas

Elife· July 2020

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Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid.
Isabel V L Wilkinson, Kelly J Perkins, Hannah Dugdale, Lee Moir, Aini Vuorinen, Philip D Charles

Angew Chem Int Ed Engl· February 2020

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Identification of antigens presented by MHC for vaccines against tuberculosis.
Paulo Bettencourt, Julius Müller, Annalisa Nicastri, Daire Cantillon, Meera Madhavan, Philip D Charles

NPJ Vaccines· January 2020

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