Publications by authors named "Philip D Dunne"

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Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation.
Georgios Kanellos, Chiara Giacomelli, Alexander Raven, Nikola Vlahov, Hu Jin, Philip D Dunne

Nat Genet· December 2025

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Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding.
Zhichun Gao, Yuhan Gao, Louise R Dutton, Melibea Berzosa Suner, Grace Todd, Philip D Dunne

J Biol Chem· November 2025

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MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance.
Mark White, Megan L Mills, Laura M Millett, Kathryn Gilroy, Yourae Hong, Philip D Dunne

Nature· November 2025

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Stromal cells modulate innate immune cell phenotype and function in colorectal cancer via the Sialic acid/Siglec axis.
Aoise O'Neill, Norashikin Zakaria, Courtney Bull, Hannah Egan, Shania M Corry, Philip D Dunne

J Immunother Cancer· October 2025

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Loss of colonic fidelity enables multilineage plasticity and metastasis.
Patrizia Cammareri, Michela Raponi, Yourae Hong, Caroline V Billard, Nat Peckett, Philip D Dunne

Nature· August 2025

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Restoration of NOX4 signalling reverses endothelial colony-forming cell angiogenic dysfunction associated with experimental and clinical diabetes.
Karla M O'Neill, Kevin S Edgar, Shun Hay Pun, David C Campbell, Tinrui Toh, Philip D Dunne

Stem Cell Res Ther· June 2025

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Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis.
Ibrahim Al Bakir, Kit Curtius, George D Cresswell, Heather E Grant, Nadia Nasreddin, Philip D Dunne

Gut· April 2025

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Targeting the PREX2/RAC1/PI3Kβ Signaling Axis Confers Sensitivity to Clinically Relevant Therapeutic Approaches in Melanoma.
Catriona A Ford, Dana Koludrovic, Patricia P Centeno, Mona Foth, Elpida Tsonou, Philip D Dunne

Cancer Res· February 2025

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Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data.
Courtney Bull, Ryan M Byrne, Natalie C Fisher, Shania M Corry, Raheleh Amirkhah, Philip D Dunne

Sci Rep· December 2024

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Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids.
Hojjat Naderi-Meshkin, Wiwit A Wahyu Setyaningsih, Andrew Yacoub, Garrett Carney, Victoria A Cornelius, Philip D Dunne

Stem Cells· September 2024

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Tumor-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signaling.
Niamh A Leonard, Shania M Corry, Eileen Reidy, Hannah Egan, Grace O'Malley, Philip D Dunne

iScience· September 2024

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Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures.
Umair Mahmood, Andrew Blake, Sanjay Rathee, Leslie Samuel, Graeme Murray, Philip D Dunne

Cancer Res Commun· July 2024

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Low coverage whole genome sequencing of low-grade dysplasia strongly predicts colorectal cancer risk in ulcerative colitis.
Ibrahim Al Bakir, Kit Curtius, George D Cresswell, Heather E Grant, Nadia Nasreddin, Philip D Dunne

medRxiv· July 2024

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Radiation-induced changes in gene expression in rectal cancer specimens.
Lily Victoria Sarah Hillson, Ashley Kathryn McCulloch, Joanne Edwards, Philip David Dunne, Sean Michael O'Cathail

Clin Transl Oncol· June 2024

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Author Correction: Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer.
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Philip D Dunne

Nat Genet· June 2024

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Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer.
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Philip D Dunne

Nat Genet· March 2024

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Molecular pathological classification of colorectal cancer-an update.
Philip D Dunne, Mark J Arends

Virchows Arch· February 2024

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Correction to: Molecular pathological classification of colorectal cancer-an update.
Philip D Dunne, Mark J Arends

Virchows Arch· February 2024

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PLAC8-Mediated Activation of NOX4 Signalling Restores Angiogenic Function of Endothelial Colony-Forming Cells in Experimental Hypoxia.
Shun Hay Pun, Karla M O'Neill, Kevin S Edgar, Eleanor K Gill, Arya Moez, Philip D Dunne

Cells· September 2023

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β-Catenin Drives Butyrophilin-like Molecule Loss and γδ T-cell Exclusion in Colon Cancer.
Toshiyasu Suzuki, Anna Kilbey, Nuria Casa-Rodríguez, Amy Lawlor, Anastasia Georgakopoulou, Philip D Dunne

Cancer Immunol Res· August 2023

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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment.
Hannah Egan, Oliver Treacy, Kevin Lynch, Niamh A Leonard, Grace O'Malley, Philip D Dunne

Cell Rep· May 2023

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MmCMS: mouse models' consensus molecular subtypes of colorectal cancer.
Raheleh Amirkhah, Kathryn Gilroy, Sudhir B Malla, Tamsin R M Lannagan, Ryan M Byrne, Philip D Dunne

Br J Cancer· March 2023

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Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Dustin J Flanagan, Raheleh Amirkhah, David F Vincent, Nuray Gunduz, Pauline Gentaz, Philip D Dunne

Nat Commun· January 2023

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Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Dustin J Flanagan, Raheleh Amirkhah, David F Vincent, Nuray Gunduz, Pauline Gentaz, Philip D Dunne

Nat Commun· December 2022

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Distinct Molecular Profiles of Sporadic Early-Onset Colorectal Cancer: A Population-Based Cohort and Systematic Review.
Ashleigh C Hamilton, Finian J Bannon, Philip D Dunne, Jacqueline James, Stephen McQuaid

Gastro Hep Adv· November 2022

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