Publications by authors named "Philip D Rye"

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Low Molecular Weight Alginate Oligosaccharides as Alternatives to PEG for Enhancement of the Diffusion of Cationic Nanoparticles Through Cystic Fibrosis Mucus.
Ruhina Maeshima, Aristides D Tagalakis, Dafni Gyftaki-Venieri, Stuart A Jones, Philip D Rye

Adv Healthc Mater· January 2025

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A chemo-enzymatic method for preparation of saturated oligosaccharides from alginate and other uronic acid-containing polysaccharides.
Mina Gravdahl, Olav A Aarstad, Agnes B Petersen, Stina G Karlsen, Ivan Donati, Philip D Rye

Carbohydr Polym· November 2024

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Structure-Activity Relationships of Low Molecular Weight Alginate Oligosaccharide Therapy against .
Manon F Pritchard, Lydia C Powell, Jennifer Y M Adams, Georgina Menzies, Saira Khan, Philip D Rye

Biomolecules· September 2023

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Alginate oligosaccharides enhance the antifungal activity of nystatin against candidal biofilms.
Lydia C Powell, Jennifer Y M Adams, Sadik Quoraishi, Charlène Py, Anaϊs Oger, Philip D Rye

Front Cell Infect Microbiol· February 2023

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Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection.
Rianald Fischer, Carsten Schwarz, Rebecca Weiser, Eshwar Mahenthiralingam, Knut Smerud, Philip D Rye

J Cyst Fibros· September 2022

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Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment.
Joana Stokniene, Mathieu Varache, Philip D Rye, Katja E Hill, David W Thomas

Sci Rep· March 2022

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Implementation of microbiota analysis in clinical trials for cystic fibrosis lung infection: Experience from the OligoG phase 2b clinical trials.
Rebecca Weiser, Philip D Rye, Eshwar Mahenthiralingam

J Microbiol Methods· February 2021

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Phenotypic and Genotypic Adaptations in Pseudomonas aeruginosa Biofilms following Long-Term Exposure to an Alginate Oligomer Therapy.
Juliette L Oakley, Rebecca Weiser, Lydia C Powell, Julian Forton, Eshwar Mahenthiralingam, Philip D Rye

mSphere· January 2021

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Bi-Functional Alginate Oligosaccharide-Polymyxin Conjugates for Improved Treatment of Multidrug-Resistant Gram-Negative Bacterial Infections.
Joana Stokniene, Lydia C Powell, Olav A Aarstad, Finn L Aachmann, Philip D Rye

Pharmaceutics· November 2020

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Exploiting Mannuronan C-5 Epimerases in Commercial Alginate Production.
Anne Tøndervik, Olav A Aarstad, Randi Aune, Susan Maleki, Philip D Rye

Mar Drugs· November 2020

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Inhaled dry powder alginate oligosaccharide in cystic fibrosis: a randomised, double-blind, placebo-controlled, crossover phase 2b study.
Silke van Koningsbruggen-Rietschel, Jane C Davies, Tacjana Pressler, Rainald Fischer, Gordon MacGregor, Philip D Rye

ERJ Open Res· October 2020

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Cellulose Nanofibril Formulations Incorporating a Low-Molecular-Weight Alginate Oligosaccharide Modify Bacterial Biofilm Development.
Alison A Jack, Henriette R Nordli, Lydia C Powell, Damian J J Farnell, Brita Pukstad, Philip D Rye

Biomacromolecules· August 2019

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Alginate Oligosaccharide-Induced Modification of the and Quorum-Sensing Systems in Pseudomonas aeruginosa.
Alison A Jack, Saira Khan, Lydia C Powell, Manon F Pritchard, Konrad Beck, Philip D Rye

Antimicrob Agents Chemother· May 2018

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A Low-Molecular-Weight Alginate Oligosaccharide Disrupts Pseudomonal Microcolony Formation and Enhances Antibiotic Effectiveness.
Manon F Pritchard, Lydia C Powell, Alison A Jack, Kate Powell, Konrad Beck, Philip D Rye

Antimicrob Agents Chemother· September 2017

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OligoG CF-5/20 normalizes cystic fibrosis mucus by chelating calcium.
Anna Ermund, Christian V Recktenwald, Gudmund Skjåk-Braek, Lauren N Meiss, Edvar Onsøyen, Philip D Rye

Clin Exp Pharmacol Physiol· June 2017

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The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption.
Manon F Pritchard, Lydia C Powell, Saira Khan, Peter C Griffiths, Omar T Mansour, Philip D Rye

Sci Rep· March 2017

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A novel guluronate oligomer improves intestinal transit and survival in cystic fibrosis mice.
Megan Vitko, Dana M Valerio, Philip D Rye, Edvar Onsøyen, Astrid H Myrset

J Cyst Fibros· November 2016

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OligoG CF-5/20 Disruption of Mucoid Pseudomonas aeruginosa Biofilm in a Murine Lung Infection Model.
Wang Hengzhuang, Zhijun Song, Oana Ciofu, Edvar Onsøyen, Philip D Rye

Antimicrob Agents Chemother· May 2016

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A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease.
Manon F Pritchard, Lydia C Powell, Georgina E Menzies, Paul D Lewis, Karl Hawkins, Philip D Rye

Mol Pharm· March 2016

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A nanoscale characterization of the interaction of a novel alginate oligomer with the cell surface and motility of Pseudomonas aeruginosa.
Lydia C Powell, Manon F Pritchard, Charlotte Emanuel, Edvar Onsøyen, Philip D Rye

Am J Respir Cell Mol Biol· March 2014

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