Publications by authors named "Philipp A Jaeger"

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Co-targeting SOS1 enhances the antitumor effects of KRAS inhibitors by addressing intrinsic and acquired resistance.
Venu Thatikonda, Hengyu Lyu, Sabine Jurado, Kaja Kostyrko, Christopher A Bristow, Philipp A Jaeger

Nat Cancer· September 2024

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Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays.
Thomas Gerstberger, Helmut Berger, Frank H Büttner, Michael Gmachl, Dirk Kessler, Philipp A Jaeger

J Med Chem· July 2024

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Combined KRAS and SOS1 inhibition enhances and extends the anti-tumor response in KRAS-driven cancers by addressing intrinsic and acquired resistance.
Venu Thatikonda, Hengyu Lu, Sabine Jurado, Kaja Kostyrko, Christopher A Bristow, Philipp A Jaeger

bioRxiv· January 2023

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Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response.
Erica Silva, Manuel Michaca, Brenton Munson, Gordon J Bean, Philipp A Jaeger

G3 (Bethesda)· September 2020

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The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins.
Sonya Neal, Philipp A Jaeger, Sascha H Duttke, Christopher Benner, Christopher K Glass

Mol Cell· March 2018

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The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins.
Sonya Neal, Philipp A Jaeger, Sascha H Duttke, Christopher Benner, Christopher K Glass

Mol Cell· January 2018

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Systematic Gene-to-Phenotype Arrays: A High-Throughput Technique for Molecular Phenotyping.
Philipp A Jaeger, Lilia Ornelas, Cameron McElfresh, Lily R Wong, Randolph Y Hampton

Mol Cell· January 2018

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Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.
Philipp A Jaeger, Kurt M Lucin, Markus Britschgi, Badri Vardarajan, Ruo-Pan Huang

Mol Neurodegener· May 2016

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Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA.
Andrew M Gross, Philipp A Jaeger, Jason F Kreisberg, Katherine Licon, Kristen L Jepsen

Mol Cell· April 2016

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Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain.
Philipp A Jaeger, Kurt M Lucin, Markus Britschgi, Badri Vardarajan, Ruo-Pan Huang

Mol Neurodegener· April 2016

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Beyond Agar: Gel Substrates with Improved Optical Clarity and Drug Efficiency and Reduced Autofluorescence for Microbial Growth Experiments.
Philipp A Jaeger, Cameron McElfresh, Lily R Wong, Trey Ideker

Appl Environ Microbiol· August 2015

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Development of ultra-high-density screening tools for microbial "omics".
Gordon J Bean, Philipp A Jaeger, Sondra Bahr, Trey Ideker

PLoS One· October 2014

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ALK5-dependent TGF-β signaling is a major determinant of late-stage adult neurogenesis.
Yingbo He, Hui Zhang, Andrea Yung, Saul A Villeda, Philipp A Jaeger

Nat Neurosci· July 2014

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TDP-43 frontotemporal lobar degeneration and autoimmune disease.
Zachary A Miller, Katherine P Rankin, Neill R Graff-Radford, Leonel T Takada, Virginia E Sturm, Philipp A Jaeger

J Neurol Neurosurg Psychiatry· September 2013

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Modeling transcriptome dynamics in a complex world.
Philipp A Jaeger, Colleen Doherty, Trey Ideker

Cell· December 2012

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Beclin 1 complex in autophagy and Alzheimer disease.
Philipp A Jaeger, Tony Wyss-Coray

Arch Neurol· October 2010

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Regulation of amyloid precursor protein processing by the Beclin 1 complex.
Philipp A Jaeger, Fiona Pickford, Chung-Huan Sun, Kurt M Lucin, Eliezer Masliah

PLoS One· June 2010

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All-you-can-eat: autophagy in neurodegeneration and neuroprotection.
Philipp A Jaeger, Tony Wyss-Coray

Mol Neurodegener· April 2009

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The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
Fiona Pickford, Eliezer Masliah, Markus Britschgi, Kurt Lucin, Ramya Narasimhan, Philipp A Jaeger

J Clin Invest· June 2008

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