Publications by authors named "Philipp Demuth"

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Targeting PARP-1 and DNA Damage Response Defects in Colorectal Cancer Chemotherapy with Established and Novel PARP Inhibitors.
Philipp Demuth, Lea Thibol, Anna Lemsch, Felix Potlitz, Lukas Schulig

Cancers (Basel)· October 2024

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p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol.
Max J Carlsson, Anastasia S Vollmer, Philipp Demuth, Daniel Heylmann, Diana Reich

Cell Death Dis· November 2022

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The Mitochondrial Disruptor Devimistat (CPI-613) Synergizes with Genotoxic Anticancer Drugs in Colorectal Cancer Therapy in a Bim-Dependent Manner.
Carina Arnold, Philipp Demuth, Nina Seiwert, Simon Wittmann, Kerstin Boengler

Mol Cancer Ther· January 2022

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Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-type and Mutant Colorectal Cancer.
Apisada Jiso, Philipp Demuth, Madeleine Bachowsky, Manuel Haas, Nina Seiwert

Cancers (Basel)· June 2021

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Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.
Nina Seiwert, Sabine Wecklein, Philipp Demuth, Solveig Hasselwander, Talke A Kemper

Cell Death Dis· September 2020

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Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities.
Carina Neitzel, Philipp Demuth, Simon Wittmann, Jörg Fahrer

Cancers (Basel)· June 2020

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Zinc overload mediated by zinc oxide nanoparticles as innovative anti-tumor agent.
Nadine Wiesmann, Martin Kluenker, Philipp Demuth, Walburgis Brenner, Wolfgang Tremel

J Trace Elem Med Biol· January 2019

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