Publications by authors named "Philippe Frossard"

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NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke.
Juan Lorenzo Rodriguez-Flores, Shareef Khalid, Neelroop Parikshak, Asif Rasheed, Bin Ye, Philippe Frossard

Nat Commun· September 2024

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South Asian medical cohorts reveal strong founder effects and high rates of homozygosity.
Jeffrey D Wall, J Fah Sathirapongsasuti, Ravi Gupta, Asif Rasheed, Radha Venkatesan, Philippe Frossard

Nat Commun· June 2023

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Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.
Allan Gurtan, John Dominy, Shareef Khalid, Linh Vong, Shari Caplan, Philippe Frossard

PLoS Genet· April 2022

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Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
Eric L Harshfield, Eric B Fauman, David Stacey, Dirk S Paul, Daniel Ziemek, Philippe Frossard

BMC Med· September 2021

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Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Praveen Surendran, Elena V Feofanova, Najim Lahrouchi, Ioanna Ntalla, Savita Karthikeyan, Philippe Frossard

Nat Genet· May 2021

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Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Praveen Surendran, Elena V Feofanova, Najim Lahrouchi, Ioanna Ntalla, Savita Karthikeyan, Philippe Frossard

Nat Genet· December 2020

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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
A Mesut Erzurumluoglu, Mengzhen Liu, Victoria E Jackson, Daniel R Barnes, Gargi Datta, Philippe Frossard

Mol Psychiatry· October 2020

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An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors.
Eric L Harshfield, Albert Koulman, Daniel Ziemek, Luke Marney, Eric B Fauman, Philippe Frossard

J Proteome Res· June 2019

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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Jason Flannick, Josep M Mercader, Christian Fuchsberger, Miriam S Udler, Anubha Mahajan, Philippe Frossard

Nature· June 2019

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Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.
John W Cole, Huichun Xu, Kathleen Ryan, Thomas Jaworek, Nicole Dueker, Philippe Frossard

PLoS One· April 2019

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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
Anubha Mahajan, Jennifer Wessel, Sara M Willems, Wei Zhao, Neil R Robertson, Philippe Frossard

Nat Genet· April 2018

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Exome-wide association study of plasma lipids in >300,000 individuals.
Dajiang J Liu, Gina M Peloso, Haojie Yu, Adam S Butterworth, Xiao Wang, Philippe Frossard

Nat Genet· December 2017

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Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung-Jin Lee, Adam S Butterworth, Philippe Frossard

Nat Genet· October 2017

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Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis.
Danish Saleheen, Philip C Haycock, Wei Zhao, Asif Rasheed, Adam Taleb, Philippe Frossard

Lancet Diabetes Endocrinol· July 2017

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Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
Joanna M M Howson, Wei Zhao, Daniel R Barnes, Weang-Kee Ho, Robin Young, Philippe Frossard

Nat Genet· July 2017

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Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.
Siddhartha Jaiswal, Pradeep Natarajan, Alexander J Silver, Christopher J Gibson, Alexander G Bick, Philippe Frossard

N Engl J Med· July 2017

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ANGPTL3 Deficiency and Protection Against Coronary Artery Disease.
Nathan O Stitziel, Amit V Khera, Xiao Wang, Andrew J Bierhals, A Christina Vourakis, Philippe M Frossard

J Am Coll Cardiol· April 2017

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Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.
Danish Saleheen, Pradeep Natarajan, Irina M Armean, Wei Zhao, Asif Rasheed, Philippe Frossard

Nature· April 2017

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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Praveen Surendran, Fotios Drenos, Robin Young, Helen Warren, James P Cook, Philippe Frossard

Nat Genet· October 2016

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Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.
Tanya Keenan, Wei Zhao, Asif Rasheed, Weang K Ho, Rainer Malik, Philippe Frossard

J Am Coll Cardiol· February 2016

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Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
Minako Imamura, Atsushi Takahashi, Toshimasa Yamauchi, Kazuo Hara, Kazuki Yasuda, Philippe Frossard

Nat Commun· January 2016

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Physical activity, smoking, and genetic predisposition to obesity in people from Pakistan: the PROMIS study.
Shafqat Ahmad, Wei Zhao, Frida Renström, Asif Rasheed, Maria Samuel, Philippe Frossard

BMC Med Genet· December 2015

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A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
Majid Nikpay, Anuj Goel, Hong-Hee Won, Leanne M Hall, Christina Willenborg, Philippe Frossard

Nat Genet· October 2015

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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Nat Genet· March 2014

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Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
Richa Saxena, Danish Saleheen, Latonya F Been, Martha L Garavito, Timothy Braun, Philippe Frossard

Diabetes· May 2013

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