Publications by authors named "Philippe Loiseau"

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Are hydrophilic deep eutectic solvents a potential vehicle for topical delivery of Amphotericin B against cutaneous leishmaniasis? An investigation of physicochemical properties, tolerability and antileishmanial efficacy.
Cảnh Hưng Nguyễn, Catherine Cailleau, Natalie Fournier, Luc Augis, Françoise Mercier-Nomé, Philippe M Loiseau

Int J Pharm· December 2025

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Re-sensitization of antimony-resistant Leishmania by highly potent Sb-porphyrin through the involvement of ERG6-coding gene.
Ellen Gonçalves de Oliveira, Juliane Sousa Lanza, Sandrine Cojean, Paulo Otávio L Moreira, Luiza Guimarães Tunes, Philippe M Loiseau

Biomed Pharmacother· June 2025

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Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy.
Lhana Tisseur, Cédric Logé, Sandrine Cojean, Khadidiatou Gassama, Lilian Karcher, Philippe M Loiseau

RSC Med Chem· June 2025

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Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition.
Lhana Tisseur, Sandrine Cojean, Khadidiatou Gassama, Cédric Logé, Fabrice Pagniez, Philippe M Loiseau

ChemMedChem· March 2025

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Effect of Phlebotomus papatasi on the fitness, infectivity and antimony-resistance phenotype of antimony-resistant Leishmania major Mon-25.
Nalia Mekarnia, Kamal-Eddine Benallal, Jovana Sádlová, Barbora Vojtková, Aurélie Mauras, Philippe M Loiseau

Int J Parasitol Drugs Drug Resist· August 2024

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Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4-tetrahydro-thiopyran-4-one -Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones.
Thibault Gendron, Don Antoine Lanfranchi, Nicole I Wenzel, Hripsimée Kessedjian, Beate Jannack, Philippe M Loiseau

Molecules· April 2024

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The Synthesis of 2'-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities.
Imen Abid, Wassim Moslah, Sandrine Cojean, Nicolas Imbert, Philippe M Loiseau

Molecules· April 2024

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Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in .
Sameh Obeid, Eloisa Berbel-Manaia, Valérie Nicolas, Indira Dennemont, Julien Barbier, Philippe M Loiseau

iScience· November 2023

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Synthesis of new 3-acetyl-1,3,4-oxadiazolines combined with pyrimidines as antileishmanial and antiviral agents.
Saida Lachhab, Az-Eddine El Mansouri, Ahmad Mehdi, Indira Dennemont, Johan Neyts, Philippe M Loiseau

Mol Divers· October 2023

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Supramolecular assemblies from antimony(V) complexes for the treatment of leishmaniasis.
Cynthia Demicheli, Virgínia M R Vallejos, Juliane S Lanza, Guilherme S Ramos, Bruno R Do Prado, Philippe M Loiseau

Biophys Rev· August 2023

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Mechanochemical Studies on Coupling of Hydrazines and Hydrazine Amides with Phenolic and Furanyl Aldehydes-Hydrazones with Antileishmanial and Antibacterial Activities.
Anna Kapusterynska, Christian Bijani, Damian Paliwoda, Laure Vendier, Valérie Bourdon, Philippe Marie Loiseau

Molecules· July 2023

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Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides.
Christina L Koumpoura, Michel Nguyen, Christian Bijani, Laure Vendier, Elena G Salina, Philippe M Loiseau

ACS Omega· October 2022

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Stimulation of excystment by enzyme treatment and consequences on trophozoite growth.
Zineb Fechtali-Moute, Philippe M Loiseau, Sébastien Pomel

Front Cell Dev Biol· September 2022

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Pharmacokinetics, biodistribution, and activity of Amphotericin B-loaded nanocochleates on the Leishmania donovani murine visceral leishmaniasis model.
Antonio Lipa Castro, Sébastien Pomel, Catherine Cailleau, Natalie Fournier, Indira Dennemont, Philippe M Loiseau

Int J Pharm· August 2022

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Nanoassemblies from Amphiphilic Sb Complexes Target Infection Sites in Models of Visceral and Cutaneous Leishmaniases.
Juliane S Lanza, Virginia M R Vallejos, Guilherme S Ramos, Ana Carolina B de Oliveira, Cynthia Demicheli, Philippe M Loiseau

Pharmaceutics· August 2022

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Targeting chalcone binding sites in living Leishmania using a reversible fluorogenic benzochalcone probe.
Ariane S Batista, Suellen D S Oliveira, Sébastien Pomel, Pierre-Henri Commere, Valérie Mazan, Philippe M Loiseau

Biomed Pharmacother· May 2022

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Formulation of Amphotericin B in PEGylated Liposomes for Improved Treatment of Cutaneous Leishmaniasis by Parenteral and Oral Routes.
Guilherme S Ramos, Virgínia M R Vallejos, Gabriel S M Borges, Raquel M Almeida, Izabela M Alves, Philippe M Loiseau

Pharmaceutics· May 2022

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The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates.
Philippe M Loiseau, Kaluvu Balaraman, Gillian Barratt, Sébastien Pomel, Rémy Durand

Molecules· April 2022

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Minor Impact of A258D Mutation on Biochemical and Enzymatic Properties of GDP-Mannose Pyrophosphorylase.
Wei Mao, Noureddine Lazar, Herman van Tilbeurgh, Philippe M Loiseau, Sébastien Pomel

Microorganisms· January 2022

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Anti-protozoal and anti-fungal evaluation of 3,5-disubstituted 1,2-dioxolanes.
Alexis Pinet, Sandrine Cojean, Linh Thuy Nguyen, Pedro Vásquez-Ocmín, Alexandre Maciuk, Philippe M Loiseau

Bioorg Med Chem Lett· September 2021

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An adamantamine derivative as a drug candidate for the treatment of visceral leishmaniasis.
Sébastien Pomel, Sandrine Cojean, Valérie Pons, Jean-Christophe Cintrat, Laetitia Nguyen, Philippe M Loiseau

J Antimicrob Chemother· September 2021

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Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis.
Doumet Georges Helou, Aurélie Mauras, François Fasquelle, Juliane Sousa Lanza, Philippe M Loiseau

PLoS Negl Trop Dis· August 2021

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Drugs used for the treatment of cerebral and disseminated infections caused by free-living amoebae.
Alexandre Taravaud, Zineb Fechtali-Moute, Philippe M Loiseau, Sébastien Pomel

Clin Transl Sci· May 2021

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In vitro antileishmanial potentialities of essential oils from Citrus limon and Pistacia lentiscus harvested in Tunisia.
Zeineb Maaroufi, Sandrine Cojean, Philippe M Loiseau, Marwa Yahyaoui, Florence Agnely

Parasitol Res· April 2021

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Alkyl-Resorcinol Derivatives as Inhibitors of GDP-Mannose Pyrophosphorylase with Antileishmanial Activities.
Hélène Levaique, Olivier Pamlard, Cécile Apel, Jérôme Bignon, Margaux Arriola, Philippe M Loiseau

Molecules· March 2021

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