Publications by authors named "Johan Neyts"

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2
2-amido-3-aryl-4-methyl-thiazole derivatives as broad-spectrum anti-rhinoviral agents.
Sileshi Abera Ayele, Hye Lim Lee, Céline Sablon, Alba Reneesh, Kyeongdeok Seo, Johan Neyts

Eur J Med Chem· January 2026

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Functional Humoral Response During Intranasal Convalescent Plasma Prophylaxis for Severe Acute Respiratory Syndrome Coronavirus 2.
Caro Verbrugghe, Rana Abdelnabi, Tania Maes, Lotte Coelmont, Birgit Weynand, Johan Neyts

J Infect Dis· December 2025

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Antiviral activities of phenylalanine derivatives carrying carboxylic acid bioisosteres against chikungunya and parainfluenza virus type 3.
Merve Camcı Eren, Görkem Güngör, Steven De Jonghe, Dirk Jochmans, Mehmet Özbil, Johan Neyts

Bioorg Med Chem· December 2025

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Immunological and transcriptomic profile of chimeric live-attenuated Zika vaccine linked to protection in non-human primates.
Ji Ma, Bert Malengier-Devlies, Babs E Verstrepen, Yeranddy A Alpizar, Thomas Vercruysse, Johan Neyts

Nat Commun· December 2025

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Thiazolyl 4-carboxylate ketone as a new warhead for a highly potent SARS-CoV-2 main protease inhibitor.
Maria A Theodoropoulou, Haifa El Kilani, Christiana Mantzourani, Dirk Jochmans, Johan Neyts

Eur J Med Chem· November 2025

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Correction to "Discovery of Novel Arylethynyltriazole Ribonucleosides with Selective and Effective Antiviral and Antiproliferative Activity".
Jinqiao Wan, Yi Xia, Yang Liu, Menghua Wang, Palma Rocchi, Johan Neyts

J Med Chem· October 2025

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1'-Cyanocytidine-5'-isobutyryl is a potent SARS-CoV-2 inhibitor in culture and infected Syrian hamsters.
Franck Amblard, Mahesh Kasthuri, Julia C LeCher, Sijia Tao, Ramyani De, Johan Neyts

Sci Adv· October 2025

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Design, synthesis and evaluation of arylpurine-based sinefungin mimetics as zika virus methyltransferase inhibitors.
Natalia Del Río, Iván Arribas-Álvarez, José-María Orduña, Priscila Sutto-Ortiz, Johan Neyts

RSC Adv· October 2025

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Synthesis and antiviral activity of thiazolyl hydrazones against dengue virus.
Mohd Usman Mohd Siddique, Deepak Shilkar, Vasavi Garisetti, Sheikh Murtuja, Suzanne Kaptein, Johan Neyts

Bioorg Med Chem Lett· October 2025

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Proliferative Cell Targeting and Epithelial Cell Turnover Fuels Hepatitis E Virus Replication in Human Intestinal Enteroids.
Nanci Santos-Ferreira, Xin Zhang, Laura Corneillie, Jana Van Dycke, Winston Chiu, Johan Neyts

Gastro Hep Adv· October 2025

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Meeting report: 38th international conference on antiviral research in Las Vegas, United States of America, March 17-21, 2025.
Robert Jordan, Nancie M Archin, Valeria Cagno, Joy Y Feng, Haitao Guo, Johan Neyts

Antiviral Res· September 2025

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High-throughput split-GFP antiviral screening assay against fusogenic paramyxoviruses.
Laura Vandemaele, Thibault Francken, Joost Schepers, Winston Chiu, Niels Cremers, Johan Neyts

Antiviral Res· September 2025

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The Indispensable Value of Small-Molecule Antivirals in Epidemic and Pandemic Preparedness.
Ruxandra Draghia-Akli, Nina M Hill, Bruce Altevogt, Kenneth Bradley, Kelly Chibale, Johan Neyts

Clin Infect Dis· September 2025

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The multifaceted role of the viral 2A protease in enterovirus replication and antagonism of host antiviral responses.
Jelle G Schipper, Chiara Aloise, Sereina O Sutter, Marleen Zwaagstra, Arno L W van Vliet, Johan Neyts

PLoS Pathog· August 2025

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Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo.
Sam Verwimp, Jessica Wagoner, Elijah Gabriela Arenas, Lander De Coninck, Rana Abdelnabi, Johan Neyts

Antiviral Res· July 2025

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Discovery and Preclinical Profile of ALG-097558, a Pan-Coronavirus 3CLpro Inhibitor.
Dorothée Bardiot, David C McGowan, Kusum Gupta, Jerome Deval, Sandra Chang, Johan Neyts

J Med Chem· July 2025

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PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
Marwah Karim, Manjari Mishra, Chieh-Wen Lo, Sirle Saul, Halise Busra Cagirici, Johan Neyts

Nat Commun· July 2025

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Discovery of Small Molecules Targeting Norovirus 3CL Protease by Multi-Stage Virtual Screening.
Zhongling Shi, Na Liu, Fabao Zhao, Dongwei Kang, Steven De Jonghe, Johan Neyts

Int J Mol Sci· June 2025

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Discovery of orally bioavailable Zika and West Nile Virus antiviral compounds targeting the NS2B-NS3 protease.
Nathaniel T Kenton, Haim Barr, Artem Cherepakha, Lotte Coelmont, Caroline Collard, Johan Neyts

bioRxiv· June 2025

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Open-science discovery of DNDI-6510, a compound that addresses genotoxic and metabolic liabilities of the COVID Moonshot SARS-CoV-2 Mpro lead inhibitor.
Ed J Griffen, Daren Fearon, Briana L McGovern, Lizbe Koekemoer, Blake H Balcomb, Johan Neyts

bioRxiv· June 2025

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Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base.
Sieglinde De Cae, Inge Van Molle, Loes van Schie, Sophie R Shoemaker, Julie Deckers, Johan Neyts

Nat Commun· May 2025

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A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein.
Ellen Van Damme, Pravien Abeywickrema, Yanting Yin, Jiexiong Xie, Sofie Jacobs, Johan Neyts

Nature· April 2025

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A coronavirus assembly inhibitor that targets the viral membrane protein.
Manon Laporte, Dirk Jochmans, Dorothée Bardiot, Lowiese Desmarets, Oliver J Debski-Antoniak, Johan Neyts

Nature· April 2025

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6-Chlorocoumarin Conjugates with Nucleobases and Nucleosides as Potent Anti-Hepatitis C Virus Agents.
Shu-Yu Lin, Wen-Chieh Huang, Shwu-Chen Tsay, Johan Neyts, Pieter Leyssen

Molecules· April 2025

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The Combination of GS-441524 (Remdesivir) and Ribavirin Results in a Potent Antiviral Effect Against Human Parainfluenza Virus 3 Infection in Human Airway Epithelial Cell Cultures and in a Mouse Infection Model.
Yuxia Lin, Birgit Weynand, Xin Zhang, Manon Laporte, Dirk Jochmans, Johan Neyts

Viruses· January 2025

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