Publications by authors named "Phillip Hylemon"

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Bile acid dysmetabolism in Bangladeshi infants associated with poor linear growth, enteric inflammation, and small intestine bacterial overgrowth.
Farah Hasan, Phillip B Hylemon, Rashidul Haque, William A Petri, Abu Syed Golam Faruque

World J Gastroenterol· November 2025

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Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes.
Sayed Obaidullah Aseem, Jing Wang, Maleeha F Kalaiger, Grayson Way, Derrick Zhao, Phillip B Hylemon

Hepatol Commun· August 2025

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Tailored Levofloxacin Incorporated Extracellular Matrix Nanoparticles for Pulmonary Infections.
Raahi Patel, Ignacio Moyano, Masahiro Sakagami, Jason D Kang, Phillip B Hylemon

Int J Mol Sci· August 2025

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An expanded metabolic pathway for androgen production by commensal bacteria.
Taojun Wang, Saeed Ahmad, Angélica Cruz-Lebrón, Sarah E Ernst, Kelly Yovani Olivos Caicedo, Phillip B Hylemon

Nat Microbiol· May 2025

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LECT2-PHB2 axis: a new mechanistic insight and therapeutic opportunity in alcohol-associated hepatitis.
Hui Li, Meiyi Song, Phillip B Hylemon, Huiping Zhou

Gut· May 2025

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Discovery of a novel regulator, 3β-sulfate-5-cholestenoic acid, of lipid metabolism and inflammation.
Yaping Wang, Arun J Sanyal, Phillip Hylemon, Shunlin Ren

Am J Physiol Endocrinol Metab· April 2025

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Gut Microbiome and Bile Acid Interactions: Mechanistic Implications for Cholangiocarcinoma Development, Immune Resistance, and Therapy.
Nan Wu, Sareh Bayatpour, Phillip B Hylemon, Sayed O Aseem, Paul J Brindley

Am J Pathol· March 2025

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Transcriptomics, lipidomics, and single-nucleus RNA sequencing integration: exploring sphingolipids in MASH-HCC progression.
Jing Zeng, Grayson Way, Nan Wu, Xixian Jiang, Yun-Ling Tai, Phillip B Hylemon

Cell Biosci· March 2025

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Bile acid dysmetabolism in Bangladeshi infants is associated with poor linear growth, enteric inflammation, and small intestine bacterial overgrowth.
Farah Hasan, Phillip B Hylemon, Rashidul Haque, William A Petri, Abu S G Faruque

medRxiv· February 2025

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Intestinal mucosal mitochondrial oxidative phosphorylation worsens with cirrhosis progression and is ameliorated with fecal microbiota transplantation.
Jing Zeng, Derrick Zhao, Grayson Way, Andrew Fagan, Michael Fuchs, Phillip B Hylemon

JCI Insight· January 2025

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Sphingosine kinase 2 (SphK2) depletion alters redox metabolism and enhances inflammation in a diet-induced MASH mouse model.
Kaitlyn G Jackson, Derrick Zhao, Lianyong Su, Marissa K Lipp, Cameron Toler, Phillip B Hylemon

Hepatol Commun· December 2024

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Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes.
Sayed Obaidullah Aseem, Grayson Way, Jing Wang, Derrick Zhao, Yunling Tai, Phillip B Hylemon

bioRxiv· November 2024

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Inhalable tobramycin EEG powder formulation for treating Pseudomonas aeruginosa-induced lung infection.
Rudra Pangeni, Surendra Poudel, Mohammad A M Momin, Dale Farkas, Caleb Dalton, Phillip Hylemon

Int J Pharm· September 2024

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Cholestenoic acid as endogenous epigenetic regulator decreases hepatocyte lipid accumulation in vitro and in vivo.
Yaping Wang, Williams M Pandak, Phillip B Hylemon, Hae-Ki Min, John Min

Am J Physiol Gastrointest Liver Physiol· February 2024

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The RIVET RCT: Rifamycin SV MMX improves muscle mass, physical function, and ammonia in cirrhosis and minimal encephalopathy.
Jasmohan S Bajaj, Andrew Fagan, Edith A Gavis, Travis Mousel, Mary L Gallagher, Phillip B Hylemon

Hepatol Commun· February 2024

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Therapeutic potential of berberine in attenuating cholestatic liver injury: insights from a PSC mouse model.
Yanyan Wang, Derrick Zhao, Lianyong Su, Yun-Ling Tai, Grayson W Way, Phillip B Hylemon

Cell Biosci· January 2024

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Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC.
Muyiwa Awoniyi, Jeremy Wang, Billy Ngo, Vik Meadows, Jason Tam, Phillip B Hylemon

Gut· April 2023

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Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis.
Joy Sarkar, Hiroaki Aoki, Rongrong Wu, Masayo Aoki, Phillip Hylemon

Ann Surg Oncol· March 2023

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Bile Acids and Biliary Fibrosis.
Sayed Obaidullah Aseem, Phillip B Hylemon, Huiping Zhou

Cells· March 2023

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Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer.
Yanyan Wang, Jing Zeng, Weidong Chen, Jiangao Fan, Phillip B Hylemon

Noncoding RNA· March 2023

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RNA binding protein HuR protects against NAFLD by suppressing long noncoding RNA H19 expression.
Yanyan Wang, Yun-Ling Tai, Grayson Way, Jing Zeng, Derrick Zhao, Phillip B Hylemon

Cell Biosci· October 2022

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Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice.
Jennifer T Wolstenholme, Justin M Saunders, Maren Smith, Jason D Kang, Phillip B Hylemon

Nat Commun· October 2022

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Bile Acids, Gut Microbiome and the Road to Fatty Liver Disease.
Phillip B Hylemon, Lianyong Su, Po-Cheng Zheng, Jasmohan S Bajaj, Huiping Zhou

Compr Physiol· December 2021

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25-Hydroxycholesterol 3-Sulfate Recovers Acetaminophen Induced Acute Liver Injury via Stabilizing Mitochondria in Mouse Models.
Yaping Wang, William M Pandak, Edward J Lesnefsky, Phillip B Hylemon, Shunlin Ren

Cells· November 2021

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Bile Acid Receptors and the Gut-Liver Axis in Nonalcoholic Fatty Liver Disease.
Rui Xue, Lianyong Su, Shengyi Lai, Yanyan Wang, Derrick Zhao, Phillip B Hylemon

Cells· October 2021

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