Publications by authors named "Phing-How Lou"

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The Novel Lipid Emulsion Vegaven Is Well Tolerated and Elicits Distinct Biological Actions Compared With a Mixed-Oil Lipid Emulsion Containing Fish Oil: A Parenteral Nutrition Trial in Piglets.
Eliana Lucchinetti, Phing-How Lou, Akash Chakravarty, Camila Schultz Marcolla, Mirielle L Pauline

J Nutr· March 2025

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Optimizing Resuscitation of the Donation after Circulatory Death Heart by Mitochondrial Protection in a Female Porcine Model.
Fulin Wang, Eliana Lucchinetti, Phing-How Lou, Sanaz Hatami, Akash Chakravarty

Anesthesiology· September 2024

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Novel lipid emulsion for total parenteral nutrition based on 18-carbon n-3 fatty acids elicits a superior immunometabolic phenotype in a murine model compared with standard lipid emulsions.
Eliana Lucchinetti, Phing-How Lou, Gregory Holtzhauer, Nazek Noureddine, Paulina Wawrzyniak

Am J Clin Nutr· December 2022

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Lipid emulsion rich in n-3 polyunsaturated fatty acids elicits a pro-resolution lipid mediator profile in mouse tissues and in human immune cells.
Nazek Noureddine, Ivan Hartling, Paulina Wawrzyniak, Pakeerathan Srikanthan, Phing-How Lou

Am J Clin Nutr· September 2022

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Gut microbiome and circulating bacterial DNA ("blood microbiome") in a mouse model of total parenteral nutrition: Evidence of two distinct separate microbiotic compartments.
Eliana Lucchinetti, Phing-How Lou, Philipp Lemal, Lukas Bestmann, Martin Hersberger

Clin Nutr ESPEN· June 2022

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Quantitative profiling of inflammatory and pro-resolving lipid mediators in human adolescents and mouse plasma using UHPLC-MS/MS.
Ivan Hartling, Alessio Cremonesi, Ester Osuna, Phing-How Lou, Eliana Lucchinetti

Clin Chem Lab Med· October 2021

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Novel Strategies to Prevent Total Parenteral Nutrition-Induced Gut and Liver Inflammation, and Adverse Metabolic Outcomes.
Eliana Lucchinetti, Phing-How Lou, Paulina Wawrzyniak, Marcin Wawrzyniak, Michael Scharl

Mol Nutr Food Res· March 2021

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Choice of Lipid Emulsion Determines Inflammation of the Gut-Liver Axis, Incretin Profile, and Insulin Signaling in a Murine Model of Total Parenteral Nutrition.
Phing-How Lou, Eliana Lucchinetti, Paulina Wawrzyniak, Yasser Morsy, Marcin Wawrzyniak

Mol Nutr Food Res· March 2021

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Diabetic Rat Hearts Show More Favorable Metabolic Adaptation to Omegaven Containing High Amounts of n3 Fatty Acids Than Intralipid Containing n6 Fatty Acids.
Eliana Lucchinetti, Phing-How Lou, Martin Hersberger, Alexander S Clanachan, Michael Zaugg

Anesth Analg· September 2020

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The ER chaperone calnexin controls mitochondrial positioning and respiration.
Tomás Gutiérrez, Hong Qi, Megan C Yap, Nasser Tahbaz, Leanne A Milburn, Phing-How Lou

Sci Signal· June 2020

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Lipid Emulsion Containing High Amounts of n3 Fatty Acids (Omegaven) as Opposed to n6 Fatty Acids (Intralipid) Preserves Insulin Signaling and Glucose Uptake in Perfused Rat Hearts.
Phing-How Lou, Eliana Lucchinetti, Martin Hersberger, Alexander S Clanachan, Michael Zaugg

Anesth Analg· January 2020

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Enhanced myocardial protection in cardiac donation after circulatory death using Intralipid postconditioning in a porcine model.
Eliana Lucchinetti, Phing-How Lou, Sanaz Hatami, Xiao Qi, Alexander S Clanachan

Can J Anaesth· June 2019

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Metabolite Palmitoylcarnitine Mediates Intralipid Cardioprotection Rather Than Membrane Receptors.
Michael Zaugg, Alexander S Clanachan, Phing-How Lou, Eliana Lucchinetti

Anesthesiology· March 2019

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Differential Effects of Anesthetics and Opioid Receptor Activation on Cardioprotection Elicited by Reactive Oxygen Species-Mediated Postconditioning in Sprague-Dawley Rat Hearts.
Eliana Lucchinetti, Phing-How Lou, Manoj Gandhi, Alexander S Clanachan, Michael Zaugg

Anesth Analg· May 2018

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Postconditioning with Intralipid emulsion protects against reperfusion injury in post-infarct remodeled rat hearts by activation of ROS-Akt/Erk signaling.
Michael Zaugg, Phing-How Lou, Eliana Lucchinetti, Manoj Gandhi, Alexander S Clanachan

Transl Res· August 2017

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Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats.
Phing-How Lou, Eliana Lucchinetti, Katrina Y Scott, Yiming Huang, Manoj Gandhi

Physiol Rep· August 2017

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TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux.
Arun Raturi, Tomás Gutiérrez, Carolina Ortiz-Sandoval, Araya Ruangkittisakul, Maria Sol Herrera-Cruz, Phing-How Lou

J Cell Biol· August 2016

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Loss of Intralipid®- but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of fructose-fed rats: importance of ROS signaling.
Phing-How Lou, Eliana Lucchinetti, Liyan Zhang, Andreas Affolter, Manoj Gandhi

PLoS One· December 2015

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Propofol (Diprivan®) and Intralipid® exacerbate insulin resistance in type-2 diabetic hearts by impairing GLUT4 trafficking.
Phing-How Lou, Eliana Lucchinetti, Liyan Zhang, Andreas Affolter, Manoj Gandhi

Anesth Analg· February 2015

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The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.
Phing-How Lou, Eliana Lucchinetti, Liyan Zhang, Andreas Affolter, Marcus C Schaub

PLoS One· September 2014

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Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat.
Blair E Warren, Phing-How Lou, Eliana Lucchinetti, Liyan Zhang, Alexander S Clanachan

Am J Physiol Endocrinol Metab· March 2014

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Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury.
Phing-How Lou, Liyan Zhang, Eliana Lucchinetti, Markus Heck, Andreas Affolter

Cardiovasc Res· February 2013

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Antiproliferative effects of local anesthetics on mesenchymal stem cells: potential implications for tumor spreading and wound healing.
Eliana Lucchinetti, Ahmed E Awad, Mamoona Rahman, Jianhua Feng, Phing-How Lou

Anesthesiology· April 2012

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Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion.
Phing-How Lou, Natalia Gustavsson, Yue Wang, George K Radda, Weiping Han

PLoS One· March 2012

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Choice of anesthetic combination determines Ca2+ leak after ischemia-reperfusion injury in the working rat heart: favorable versus adverse combinations.
Michael Zaugg, Lianguo Wang, Liyan Zhang, Phing-How Lou, Eliana Lucchinetti

Anesthesiology· March 2012

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