Publications by authors named "Pierangelo Geppetti"

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Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo.
Valentina Albanese, Matilde Marini, Martina Tesi, Lorenzo Landini, Elisa Bellantoni, Pierangelo Geppetti

Eur J Med Chem· September 2025

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Targeting prostaglandin E receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation.
Romina Nassini, Lorenzo Landini, Matilde Marini, Martina Chieca, Daniel Souza Monteiro de Araújo, Pierangelo Geppetti

Nat Commun· September 2025

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Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Pierangelo Geppetti

Br J Pharmacol· August 2025

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Advanced oxidation protein products activated TRPA1 in a neuropathic multiple sclerosis model.
Patrícia Rodrigues, Julia Maria Frare, Náthaly Andrighetto Ruviaro, Diulle Spat Peres, Fernanda Tibolla Vieiro, Pierangelo Geppetti

Brain· August 2025

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Pain Signaling by GPCRs and RTKs.
Brain L Schmidt, Francesco De Logu, Romina Nassini, Pierangelo Geppetti, Nigel W Bunnett

Trends Pharmacol Sci· April 2025

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Evidence-based guidelines for the pharmacological treatment of migraine.
Raffaele Ornello, Valeria Caponnetto, Fayyaz Ahmed, Haidar M Al-Khazali, Anna Ambrosini, Pierangelo Geppetti

Cephalalgia· April 2025

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Evidence-based guidelines for the pharmacological treatment of migraine, summary version.
Raffaele Ornello, Valeria Caponnetto, Fayyaz Ahmed, Haidar M Al-Khazali, Anna Ambrosini, Pierangelo Geppetti

Cephalalgia· April 2025

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Characterisation of periorbital mechanical allodynia in the reserpine-induced fibromyalgia model in mice: The role of the Schwann cell TRPA1/NOX1 signalling pathway.
Evelyne Silva Brum, Lorenzo Landini, Daniel Souza Monteiro de Araújo, Matilde Marini, Pierangelo Geppetti

Free Radic Biol Med· March 2025

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Impact of duration of chronic migraine on long-term effectiveness of monoclonal antibodies targeting the calcitonin gene-related peptide pathway-A real-world study.
Raffaele Ornello, Francesca Baldini, Agnese Onofri, Chiara Rosignoli, Federico De Santis, Pierangelo Geppetti

Headache· January 2025

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Schwann cell transient receptor potential ankyrin 1 (TRPA1) ortholog in zebrafish larvae mediates chemotherapy-induced peripheral neuropathy.
Elisa Bellantoni, Matilde Marini, Martina Chieca, Chiara Gabellini, Erica Lucia Crapanzano, Pierangelo Geppetti

Br J Pharmacol· December 2024

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A p75 neurotrophin receptor-sparing nerve growth factor protects retinal ganglion cells from neurodegeneration by targeting microglia.
Laura Latini, Daniel Souza Monteiro De Araujo, Rosario Amato, Alessio Canovai, Lucia Buccarello, Pierangelo Geppetti

Br J Pharmacol· December 2024

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An evolving machine-learning-based algorithm to early predict response to anti-CGRP monoclonal antibodies in patients with migraine.
Marina Romozzi, Ammar Lokhandwala, Catello Vollono, Giulia Vigani, Andrea Burgalassi, Pierangelo Geppetti

Cephalalgia· December 2024

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Outcomes, unmet needs, and challenges in the management of patients who withdraw from anti-CGRP monoclonal antibodies: A prospective cohort study.
Andrea Burgalassi, Marina Romozzi, Giulia Vigani, Roberto De Icco, Bianca Raffaelli, Pierangelo Geppetti

Cephalalgia· November 2024

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Schwann cell C5aR1 co-opts inflammasome NLRP1 to sustain pain in a mouse model of endometriosis.
Mustafa Titiz, Lorenzo Landini, Daniel Souza Monteiro de Araujo, Matilde Marini, Viola Seravalli, Pierangelo Geppetti

Nat Commun· November 2024

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Exploring the multifaceted characteristics of aura in migraine: A multicenter, cross-sectional study.
Giorgio Dalla Volta, Antonio Russo, Marcello Silvestro, Raffaele Ornello, Valeria Caponnetto, Pierangelo Geppetti

Cephalalgia· November 2024

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Schwann cell TRPA1 elicits reserpine-induced fibromyalgia pain in mice.
Evelyne Silva Brum, Maria Fernanda Pessano Fialho, Daniel Souza Monteiro de Araújo, Lorenzo Landini, Matilde Marini, Pierangelo Geppetti

Br J Pharmacol· September 2024

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Perineural invasion score system and clinical outcomes in resected pancreatic cancer patients.
Filippo Nozzoli, Martina Catalano, Luca Messerini, Fabio Cianchi, Romina Nassini, Pierangelo Geppetti

Pancreatology· June 2024

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The first interim analysis of Italian patients enrolled in the real-world, Pan-European, prospective, observational, phase 4 PEARL study of fremanezumab effectiveness.
Cristina Tassorelli, Piero Barbanti, Cinzia Finocchi, Pierangelo Geppetti, Pinar Kokturk

Neurol Sci· May 2024

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Patterns of anti-CGRP mAbs use and variation of triptan consumption following treatment initiation: A descriptive drug utilization study in the Tuscany region, Italy.
Giulia Hyeraci, Olga Paoletti, Luigi Francesco Iannone, Rosa Gini, Francesco De Cesaris, Pierangelo Geppetti

Headache· December 2023

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Long-Term Treatment Over 52 Weeks with Monthly Fremanezumab in Drug-Resistant Migraine: A Prospective Multicenter Cohort Study.
Valeria Caponnetto, Antonio Russo, Marcello Silvestro, Alessandro Tessitore, Roberto De Icco, Pierangelo Geppetti

CNS Drugs· December 2023

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Retreating migraine patients in the second year with monoclonal antibodies anti-CGRP pathway: the multicenter prospective cohort RE-DO study.
Fabrizio Vernieri, Nicoletta Brunelli, Simona Guerzoni, Luigi Francesco Iannone, Carlo Baraldi, Pierangelo Geppetti

J Neurol· November 2023

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TRP Channels in Cancer: Signaling Mechanisms and Translational Approaches.
Matilde Marini, Mustafa Titiz, Daniel Souza Monteiro de Araújo, Pierangelo Geppetti, Romina Nassini

Biomolecules· October 2023

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Endometriosis and the diagnosis of different forms of migraine: an association with dysmenorrhoea.
Benedetta Pasquini, Viola Seravalli, Silvia Vannuccini, Francesco La Torre, Pierangelo Geppetti

Reprod Biomed Online· July 2023

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Migraine Treatment: Towards New Pharmacological Targets.
Marcello Silvestro, Luigi Francesco Iannone, Ilaria Orologio, Alessandro Tessitore, Gioacchino Tedeschi, Pierangelo Geppetti

Int J Mol Sci· July 2023

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Neuropathic-like Nociception and Spinal Cord Neuroinflammation Are Dependent on the TRPA1 Channel in Multiple Sclerosis Models in Mice.
Diéssica Padilha Dalenogare, Daniel Souza Monteiro de Araújo, Lorenzo Landini, Mustafa Titiz, Gaetano De Siena, Pierangelo Geppetti

Cells· May 2023

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