Publications by authors named "Pierre Nimsgern"

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Harnessing Glutamine-117 Plasticity toward Structure-Based Identification of Triazole IL-17 Inhibitors.
Matthias R Bauer, Juraj Velcicky, Alban Goetz, Pascal Furet, Pierre Nimsgern

J Med Chem· December 2025

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Discovery and Exploration of 1,3,4-Oxadiazole and α-Fluoroacrylate Containing IL-17 Inhibitors.
Juraj Velcicky, Matthias R Bauer, Achim Schlapbach, Guillaume Lapointe, Arndt Meyer, Pierre Nimsgern

J Med Chem· September 2024

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Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an Efficacious TLR7/8 Antagonist.
Claudia Betschart, Michael Faller, Florence Zink, René Hemmig, Jutta Blank, Pierre Nimsgern

ACS Med Chem Lett· April 2022

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Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4.
Robin A Fairhurst, Thomas Knoepfel, Nicole Buschmann, Catherine Leblanc, Robert Mah, Pierre Nimsgern

J Med Chem· November 2020

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Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay.
Thomas Knoepfel, Pierre Nimsgern, Sébastien Jacquier, Marjorie Bourrel, Eric Vangrevelinghe

J Med Chem· August 2020

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An Amphiphilic Polymer-Supported Strategy Enables Chemical Transformations under Anhydrous Conditions for DNA-Encoded Library Synthesis.
Yves Ruff, Roberto Martinez, Xavier Pellé, Pierre Nimsgern, Pascale Fille

ACS Comb Sci· March 2020

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