Publications by authors named "Pieter Wouters"

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Aberrant DNA methylation within circadian entrainment and clock genes two years after pediatric critical illness is associated with impaired physical and neurocognitive development.
Grégoire Coppens, Arnout B G Cramer, Ilse Vanhorebeek, Fabian Güiza, Pieter J Wouters

Clin Epigenetics· November 2025

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Brain Injury and Ketamine study (BIKe): a prospective, randomized controlled double blind clinical trial to study the effects of ketamine on therapy intensity level and intracranial pressure in severe traumatic brain injury patients.
Veerle De Sloovere, Liese Mebis, Pieter Wouters, Fabian Guïza, Eva Boonen

Trials· May 2025

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How many subjects are enough in a veterinary trial?-Literature review and insights from industrial statisticians.
Zikun Wang, Qi Cao, Qingzhi Liu, Divine Dufe, Pieter Wouters

Res Vet Sci· April 2025

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Impact of withholding early parenteral nutrition on 2-year mortality and functional outcome in critically ill adults.
Michael P Casaer, Hendrik Stragier, Greet Hermans, Alexandra Hendrickx, Pieter J Wouters

Intensive Care Med· October 2024

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Predicting adverse long-term neurocognitive outcomes after pediatric intensive care unit admission.
Felipe Kenji Nakano, Karolijn Dulfer, Ilse Vanhorebeek, Pieter J Wouters, Sascha C Verbruggen

Comput Methods Programs Biomed· June 2024

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Abnormal DNA methylation within HPA-axis genes years after paediatric critical illness.
Grégoire Coppens, Ilse Vanhorebeek, Fabian Güiza, Inge Derese, Pieter J Wouters

Clin Epigenetics· February 2024

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Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial.
Grégoire Coppens, Ilse Vanhorebeek, Ines Verlinden, Inge Derese, Pieter J Wouters

Epigenetics· December 2023

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Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU.
Jan Gunst, Yves Debaveye, Fabian Güiza, Jasperina Dubois, Astrid De Bruyn, Pieter J Wouters

N Engl J Med· September 2023

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Development and validation of the creatinine clearance predictor machine learning models in critically ill adults.
Chao-Yuan Huang, Fabian Güiza, Pieter Wouters, Liese Mebis, Giorgia Carra

Crit Care· July 2023

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Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time.
Ilse Vanhorebeek, Grégoire Coppens, Fabian Güiza, Inge Derese, Pieter J Wouters

Clin Epigenetics· July 2023

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The association of hypoglycemia with outcome of critically ill children in relation to nutritional and blood glucose control strategies.
Jan Gunst, Astrid De Bruyn, An Jacobs, Lies Langouche, Inge Derese, Pieter J Wouters

Crit Care· June 2023

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Development and validation of clinical prediction models for acute kidney injury recovery at hospital discharge in critically ill adults.
Chao-Yuan Huang, Fabian Güiza, Greet De Vlieger, Pieter Wouters, Jan Gunst

J Clin Monit Comput· February 2023

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Long-term impact of paediatric critical illness on the difference between epigenetic and chronological age in relation to physical growth.
Ines Verlinden, Grégoire Coppens, Ilse Vanhorebeek, Fabian Güiza, Inge Derese, Pieter J Wouters

Clin Epigenetics· January 2023

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Impact of tight blood glucose control within normal fasting ranges with insulin titration prescribed by the Leuven algorithm in adult critically ill patients: the TGC-fast randomized controlled trial.
Jan Gunst, Liese Mebis, Pieter J Wouters, Greet Hermans, Jasperina Dubois

Trials· September 2022

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Physical, Emotional/Behavioral, and Neurocognitive Developmental Outcomes From 2 to 4 Years After PICU Admission: A Secondary Analysis of the Early Versus Late Parenteral Nutrition Randomized Controlled Trial Cohort.
Ines Verlinden, Fabian Güiza, Karolijn Dulfer, Hanna Van Cleemput, Pieter J Wouters

Pediatr Crit Care Med· August 2022

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DNA methylation alterations in muscle of critically ill patients.
Lisa Van Dyck, Fabian Güiza, Inge Derese, Lies Pauwels, Michaël P Casaer, Pieter J Wouters

J Cachexia Sarcopenia Muscle· June 2022

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Impact of duration of critical illness and level of systemic glucocorticoid availability on tissue-specific glucocorticoid receptor expression and actions: A prospective, observational, cross-sectional human and two translational mouse studies.
Arno Téblick, Lisa Van Dyck, Nathalie Van Aerde, Sarah Van der Perre, Lies Pauwels, Pieter J Wouters

EBioMedicine· June 2022

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Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial.
Ilse Vanhorebeek, An Jacobs, Liese Mebis, Karolijn Dulfer, Renate Eveleens, Pieter J Wouters

Crit Care· May 2022

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Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?
Ilse Vanhorebeek, Govindan Malarvannan, Fabian Güiza, Giulia Poma, Inge Derese, Pieter J Wouters

Environ Int· January 2022

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C-reactive protein rise in response to macronutrient deficit early in critical illness: sign of inflammation or mediator of infection prevention and recovery.
Catherine Ingels, Lies Langouche, Jasperina Dubois, Inge Derese, Sarah Vander Perre, Pieter J Wouters

Intensive Care Med· January 2022

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Aerobic exercise capacity in long-term survivors of critical illness: secondary analysis of the post-EPaNIC follow-up study.
Nathalie Van Aerde, Philippe Meersseman, Yves Debaveye, Alexander Wilmer, Michael P Casaer, Pieter J Wouters

Intensive Care Med· December 2021

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Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness.
Ilse Vanhorebeek, Inge Derese, Jan Gunst, Pieter J Wouters, Greet Hermans

Crit Care· December 2021

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Postoperative Cerebral Oxygen Saturation in Children After Congenital Cardiac Surgery and Long-Term Total Intelligence Quotient: A Prospective Observational Study.
Giorgia Carra, Marine Flechet, An Jacobs, Sören Verstraete, Dirk Vlasselaers, Pieter Wouters

Crit Care Med· June 2021

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Five-year outcome of respiratory muscle weakness at intensive care unit discharge: secondary analysis of a prospective cohort study.
Nathalie Van Aerde, Philippe Meersseman, Yves Debaveye, Alexander Wilmer, Jan Gunst, Pieter J Wouters

Thorax· June 2021

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Time course of altered DNA methylation evoked by critical illness and by early administration of parenteral nutrition in the paediatric ICU.
Ines Verlinden, Fabian Güiza, Inge Derese, Pieter J Wouters, Koen Joosten

Clin Epigenetics· October 2020

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