Publications by authors named "Piia Takabe"

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Extracellular vesicles derived from pro-inflammatory M1 macrophages induce an inflammatory and invasive phenotype in melanoma cells.
Kaisa Mäki-Mantila, Einari A Niskanen, Kirsi Kainulainen, Laia Puig Pardas, Niina Aaltonen, Piia Takabe

Cell Commun Signal· December 2025

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Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.
Ashik Jawahar Deen, Simone Adinolfi, Jouni Härkönen, Tommi Patinen, Xiaonan Liu, Piia Takabe

Redox Biol· February 2024

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SRSF3 shapes the structure of miR-17-92 cluster RNA and promotes selective processing of miR-17 and miR-20a.
Madara Ratnadiwakara, Mohamed Nm Bahrudeen, Erika Aikio, Piia Takabe, Rebekah M Engel

EMBO Rep· July 2023

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M1 Macrophages Induce Protumor Inflammation in Melanoma Cells through TNFR-NF-κB Signaling.
Kirsi Kainulainen, Piia Takabe, Sami Heikkinen, Niina Aaltonen, Carol de la Motte

J Invest Dermatol· November 2022

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Fatty Acid Fingerprints and Hyaluronic Acid in Extracellular Vesicles from Proliferating Human Fibroblast-like Synoviocytes.
Anne-Mari Mustonen, Tommi Paakkonen, Johanna Matilainen, Kirsi Rilla, Reijo Käkelä, Piia Takabe

Int J Mol Sci· May 2022

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The Impact of Hyaluronan on Tumor Progression in Cutaneous Melanoma.
Piia Takabe, Hanna Siiskonen, Aino Rönkä, Kirsi Kainulainen, Sanna Pasonen-Seppänen

Front Oncol· January 2022

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Metformin decreases hyaluronan synthesis by vascular smooth muscle cells.
Annele Sainio, Piia Takabe, Sanna Oikari, Henriikka Salomäki-Myftari, Markku Koulu

J Investig Med· February 2020

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Melanocyte Hyaluronan Coat Fragmentation Enhances the UVB-Induced TLR-4 Receptor Signaling and Expression of Proinflammatory Mediators IL6, IL8, CXCL1, and CXCL10 via NF-κB Activation.
Piia Takabe, Riikka Kärnä, Leena Rauhala, Markku Tammi, Raija Tammi

J Invest Dermatol· September 2019

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Extracellular ATP activates hyaluronan synthase 2 () in epidermal keratinocytes via P2Y, Ca signaling, and MAPK pathways.
Leena Rauhala, Tiina Jokela, Riikka Kärnä, Geneviève Bart, Piia Takabe

Biochem J· May 2018

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UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression.
Ashik Jawahar Deen, Uma Thanigai Arasu, Sanna Pasonen-Seppänen, Antti Hassinen, Piia Takabe

Cell Mol Life Sci· August 2016

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Hyaluronan synthase 3 (HAS3) overexpression downregulates MV3 melanoma cell proliferation, migration and adhesion.
Piia Takabe, Geneviève Bart, Antti Ropponen, Kirsi Rilla, Markku Tammi

Exp Cell Res· September 2015

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Interleukin-1β-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesive Hyaluronan Coats.
Tiina Jokela, Sanna Oikari, Piia Takabe, Kirsi Rilla, Riikka Kärnä

J Biol Chem· May 2015

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Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase.
Niina Aaltonen, Juha R Savinainen, Casandra Riera Ribas, Jani Rönkkö, Anne Kuusisto, Piia Takabe

Chem Biol· March 2013

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Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling.
Sanna Pasonen-Seppänen, Piia Takabe, Michael Edward, Leena Rauhala, Kirsi Rilla

Histochem Cell Biol· December 2012

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