Publications by authors named "Pin-Ju Chueh"

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Olivomycin A Targets Epithelial-Mesenchymal Transition, Apoptosis, and Mitochondrial Quality Control in Renal Cancer Cells.
Ching-Yu Hsieh, Yih-Farng Liou, Yu-Tung Shih, Alexander S Tikhomirov, Andrey E Shchekotikhin, Pin Ju Chueh

Antioxidants (Basel)· November 2025

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Soft coral Lobophytum crassum extract inhibits migration and induces apoptosis capabilities in human oral squamous cell carcinoma cells.
Shih-Min Wang, Mei-Chin Lu, Yu-Ming Hsu, Chun-Chung Huang, Chih-Yuan Fang, Pin Ju Chueh

J Dent Sci· January 2025

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Carvacrol inhibits the progression of oral submucous fibrosis via downregulation of PVT1/miR-20a-5p-mediated pyroptosis.
Cheng-Chia Yu, Pei-Ling Hsieh, Shih-Chi Chao, Yi-Wen Liao, Chuan-Hang Yu, Pin Ju Chueh

J Cell Mol Med· September 2024

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Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells.
Atikul Islam, Yu-Chun Chang, Xiao-Chi Chen, Chia-Wei Weng, Chien-Yu Chen, Pin Ju Chueh

Elife· April 2024

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The Use of Immune Regulation in Treating Head and Neck Squamous Cell Carcinoma (HNSCC).
Che-Wei Wang, Pulak Kumar Biswas, Atikul Islam, Mu-Kuan Chen, Pin Ju Chueh

Cells· February 2024

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Essential Oils Induce ROS-Mediated Autophagy and Apoptosis by Targeting SIRT1 in Colon Cancer Cells.
Atikul Islam, Yu-Chun Chang, Nai-Wen Tsao, Sheng-Yang Wang, Pin Ju Chueh

Antioxidants (Basel)· February 2024

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Bis(chloroacetamidino)-Derived Heteroarene-Fused Anthraquinones Bind to and Cause Proteasomal Degradation of tNOX, Leading to c-Flip Downregulation and Apoptosis in Oral Cancer Cells.
Jeng Shiun Chang, Chien-Yu Chen, Alexander S Tikhomirov, Atikul Islam, Ru-Hao Liang, Pin Ju Chueh

Cancers (Basel)· September 2022

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Antibiotic heliomycin and its water-soluble 4-aminomethylated derivative provoke cell death in T24 bladder cancer cells by targeting sirtuin 1 (SIRT1).
Ming Hung Lin, Atikul Islam, Yen-Hui Liu, Chia-Wei Weng, Jun-Han Zhan, Pin Ju Chueh

Am J Cancer Res· March 2022

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Capsaicin exerts therapeutic effects by targeting tNOX-SIRT1 axis and augmenting ROS-dependent autophagy in melanoma cancer cells.
Atikul Islam, Pei-Fang Hsieh, Pei-Fen Liu, Jou-Chun Chou, Jiunn-Wang Liao, Pin Ju Chueh

Am J Cancer Res· September 2021

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Water-Soluble Heliomycin Derivatives to Target i-Motif DNA.
Alexander S Tikhomirov, Mahmoud A S Abdelhamid, Georgy Y Nadysev, George V Zatonsky, Eugene E Bykov, Pin Ju Chueh

J Nat Prod· May 2021

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Capsaicin acts through tNOX (ENOX2) to induce autophagic apoptosis in p53-mutated HSC-3 cells but autophagy in p53-functional SAS oral cancer cells.
Chin-Fang Chang, Atikul Islam, Pei-Fen Liu, Jun-Han Zhan, Pin Ju Chueh

Am J Cancer Res· October 2020

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Capsaicin Targets tNOX (ENOX2) to Inhibit G1 Cyclin/CDK Complex, as Assessed by the Cellular Thermal Shift Assay (CETSA).
Atikul Islam, Ally J Su, Zih-Ming Zeng, Pin Ju Chueh, Ming-Hung Lin

Cells· October 2019

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miR-1246 as a therapeutic target in oral submucosa fibrosis pathogenesis.
Chia-Ming Liu, Yi-Wen Liao, Pei-Ling Hsieh, Chuan-Hang Yu, Pin Ju Chueh

J Formos Med Assoc· July 2019

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Capsaicin attenuates cell migration via SIRT1 targeting and inhibition to enhance cortactin and β-catenin acetylation in bladder cancer cells.
Atikul Islam, Ya-Ting Yang, Wei-Hou Wu, Pin Ju Chueh, Ming-Hung Lin

Am J Cancer Res· June 2019

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MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-κB signaling.
K J Senthil Kumar, M Gokila Vani, Hen-Wen Hsieh, Chin-Chung Lin, Jiunn-Wang Liao, Pin-Ju Chueh

Carcinogenesis· April 2019

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Immune response evoked by tumor-associated NADH oxidase (tNOX) confers potential inhibitory effect on lung carcinoma in a mouse model.
Pei-Fang Hsieh, Pin Ju Chueh, Pei-Fen Liu, Jiunn-Wang Liao, Ming-Kun Hsieh

Am J Cancer Res· April 2019

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A one-pot analysis approach to simplify measurements of protein stability and folding kinetics.
Yi-Kai Liu, Huei-Yu Chen, Pin Ju Chueh, Pei-Fen Liu

Biochim Biophys Acta Proteins Proteom· March 2019

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Engagement with tNOX (ENOX2) to Inhibit SIRT1 and Activate p53-Dependent and -Independent Apoptotic Pathways by Novel 4,11-Diaminoanthra[2,3-]furan-5,10-diones in Hepatocellular Carcinoma Cells.
Chia-Yang Lin, Atikul Islam, Claire J Su, Alexander S Tikhomirov, Andrey E Shchekotikhin, Pin Ju Chueh

Cancers (Basel)· March 2019

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Regulation of tNOX expression through the ROS-p53-POU3F2 axis contributes to cellular responses against oxaliplatin in human colon cancer cells.
Huei-Yu Chen, Atikul Islam, Tien-Ming Yuan, Shi-Wen Chen, Pei-Fen Liu, Pin Ju Chueh

J Exp Clin Cancer Res· July 2018

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Hinokitiol ablates myofibroblast activation in precancerous oral submucous fibrosis by targeting Snail.
Hui-Wen Yang, Ming-Yi Lu, Yu-Wei Chiu, Yi-Wen Liao, Yu-Feng Huang, Pin Ju Chueh

Environ Toxicol· April 2018

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New antitumor anthra[2,3-b]furan-3-carboxamides: Synthesis and structure-activity relationship.
Alexander S Tikhomirov, Chia-Yang Lin, Yulia L Volodina, Lyubov G Dezhenkova, Victor V Tatarskiy, Pin Ju Chueh

Eur J Med Chem· March 2018

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Glabridin inhibits the activation of myofibroblasts in human fibrotic buccal mucosal fibroblasts through TGF-β/smad signaling.
Ping-Hui Lee, Pei-Ming Chu, Pei-Ling Hsieh, Hui-Wen Yang, Pin Ju Chueh

Environ Toxicol· February 2018

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Aminomethylation of heliomycin: Preparation and anticancer characterization of the first series of semi-synthetic derivatives.
Georgy Y Nadysev, Alexander S Tikhomirov, Ming-Hung Lin, Ya-Ting Yang, Lyubov G Dezhenkova, Pin Ju Chueh

Eur J Med Chem· January 2018

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Tumor-associated NADH oxidase (tNOX)-NAD+-sirtuin 1 axis contributes to oxaliplatin-induced apoptosis of gastric cancer cells.
Huei-Yu Chen, Hsiao-Ling Cheng, Yi-Hui Lee, Tien-Ming Yuan, Shi-Wen Chen, Pin Ju Chueh

Oncotarget· February 2017

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Combined Use of Zoledronic Acid Augments Ursolic Acid-Induced Apoptosis in Human Osteosarcoma Cells through Enhanced Oxidative Stress and Autophagy.
Chia-Chieh Wu, Yi-Fu Huang, Chen-Pu Hsieh, Pin-Ju Chueh, Yao-Li Chen

Molecules· November 2016

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