Publications by authors named "Pin-Yu Perera"

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Noncoding-RNA-Based Therapeutics with an Emphasis on Prostatic Carcinoma-Progress and Challenges.
Victor E Nava, Pin-Yu Perera, Nirbhay Kumar, Maneesh Jain

Vaccines (Basel)· February 2022

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Development of leading first-generation vaccines against SARS-CoV-2.
Pin-Yu Perera, Liyanage P Perera

Microbes Infect· November 2021

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Inclusion of an E7 DNA Amplification Test Improves the Robustness of Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma Diagnosis.
Pin-Yu Perera, Liyanage P Perera, Lyvouch Filkoski, Wen Chen, Jack H Lichy

World J Oncol· February 2020

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Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T-cell malignancies.
Liyanage P Perera, Meili Zhang, Masao Nakagawa, Michael N Petrus, Michiyuki Maeda, Pin-Yu Perera

Am J Hematol· September 2017

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Janus Kinase Inhibitor Tofacitinib Shows Potent Efficacy in a Mouse Model of Autoimmune Lymphoproliferative Syndrome (ALPS).
Seiji Yokoyama, Pin-Yu Perera, Seigo Terawaki, Nobumasa Watanabe, Osamu Kaminuma, Liyanage P Perera

J Clin Immunol· October 2015

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Protective-antigen (PA) based anthrax vaccines confer protection against inhalation anthrax by precluding the establishment of a systemic infection.
Tod J Merkel, Pin-Yu Perera, Gloria M Lee, Anita Verma, Toyoko Hiroi, Liyanage P Perera

Hum Vaccin Immunother· September 2013

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Tofacitinib, a janus kinase inhibitor demonstrates efficacy in an IL-15 transgenic mouse model that recapitulates pathologic manifestations of celiac disease.
Seiji Yokoyama, Pin-Yu Perera, Thomas A Waldmann, Takachika Hiroi, Liyanage P Perera

J Clin Immunol· April 2013

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The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use.
Pin-Yu Perera, Jack H Lichy, Thomas A Waldmann, Liyanage P Perera

Microbes Infect· March 2012

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Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys.
Rafal J Zielinski, Jeremy V Smedley, Pin-Yu Perera, Peter M Silvera, Thomas A Waldmann, Liyanage P Perera

Vaccine· October 2010

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Development of a highly efficacious vaccinia-based dual vaccine against smallpox and anthrax, two important bioterror entities.
Tod J Merkel, Pin-Yu Perera, Vanessa K Kelly, Anita Verma, Zara N Llewellyn, Liyanage P Perera

Proc Natl Acad Sci U S A· October 2010

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Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes.
Seiji Yokoyama, Nobumasa Watanabe, Noriko Sato, Pin-Yu Perera, Lyvouch Filkoski, Liyanage P Perera

Proc Natl Acad Sci U S A· September 2009

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Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice.
Leo L M Poon, Y H Connie Leung, John M Nicholls, Pin-Yu Perera, Jack H Lichy, Liyanage P Perera

J Immunol· March 2009

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A multi-valent vaccinia virus-based tuberculosis vaccine molecularly adjuvanted with interleukin-15 induces robust immune responses in mice.
Pin-Yu Perera, Steven C Derrick, Kristopher Kolibab, Fumiki Momoi, Masafumi Yamamoto, Liyanage P Perera

Vaccine· March 2009

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Expression of NR1, NR2A and NR2B NMDA receptor subunits is not altered in the genetically-inbred Balb/c mouse strain with heightened behavioral sensitivity to MK-801, a noncompetitive NMDA receptor antagonist.
Pin-Yu Perera, Jack H Lichy, John Mastropaolo, Richard B Rosse, Stephen I Deutsch

Eur Neuropsychopharmacol· November 2008

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The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis.
Zachary J Roberts, Nadege Goutagny, Pin-Yu Perera, Hiroki Kato, Himanshu Kumar

J Exp Med· July 2007

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TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-beta-dependent signaling in TLR4-mediated responses.
Vladimir Toshchakov, Bryan W Jones, Arnd Lentschat, Aristobolo Silva, Pin-Yu Perera

J Endotoxin Res· January 2004

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The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events.
Nilofer Qureshi, Pin-Yu Perera, Jing Shen, Guochi Zhang, Arnd Lenschat

J Immunol· August 2003

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TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.
Vladimir Toshchakov, Bryan W Jones, Pin-Yu Perera, Karen Thomas, M Joshua Cody

Nat Immunol· April 2002

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