Publications by authors named "Pinghui Feng"

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Human-specific activation of the DUX4-SLC34A2 axis by herpesviruses suppresses antiviral innate immunity.
Ming Gao, Xi Cheng, Chuchu Zhang, Jiali Ma, Xuezhang Tian, Pinghui Feng

mBio· December 2025

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HSV-1 infection induces brain cofilin hyperphosphorylation in the 5×FAD Alzheimer's Disease mouse model.
Laia Gharavi-Naeini, Zhenfeng Shu, Farhang Alem, Shu Feng, Linda D Chilin, Pinghui Feng

bioRxiv· August 2025

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Establishment and Quantification of De Novo Lytic Infection by Cell-free Kaposi's Sarcoma-Associated Herpesvirus.
Qing Zhu, Janvhi Suresh Machhar, Pinghui Feng, Chengyu Liang

J Vis Exp· August 2025

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Targeting CTP synthetase 1 to restore interferon induction and impede nucleotide synthesis in SARS-CoV-2 infection.
Youliang Rao, Chao Qin, Bianca Espinosa, Ting-Yu Wang, Shu Feng, Pinghui Feng

mBio· June 2025

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Kaposi's sarcoma-associated herpesvirus induces mitochondrial fission to evade host immune responses and promote viral production.
Qing Zhu, Robert McElroy, Janvhi Suresh Machhar, Joel Cassel, Zihan Zheng, Pinghui Feng

Nat Microbiol· June 2025

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Oral Neisseria gonorrhoeae Promotes KSHV Lytic Replication.
Shu Feng, Wen Fu, Shutong Li, Wayne Yeh, Rosemary She, Pinghui Feng

J Med Virol· April 2025

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Disrupting the OTUD4-USP7 deubiquitinase complex to suppress herpesvirus replication: a novel antiviral strategy.
Shaowei Wang, Xuezhang Tian, Yunhong Zhong, Xiaoyu Xie, Ming Gao, Pinghui Feng

PLoS Pathog· April 2025

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Pyrimidine synthesis enzyme CTP synthetase 1 suppresses antiviral interferon induction by deamidating IRF3.
Youliang Rao, Chao Qin, Ali Can Savas, Qizhi Liu, Shu Feng, Pinghui Feng

Immunity· January 2025

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Cryptic phosphoribosylase activity of NAMPT restricts the virion incorporation of viral proteins.
Shu Feng, Na Xie, Yongzhen Liu, Chao Qin, Ali Can Savas, Pinghui Feng

Nat Metab· December 2024

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The emerging roles of glutamine amidotransferases in metabolism and immune defense.
Taolin Xie, Chao Qin, Ali Can Savas, Wayne Wei Yeh, Pinghui Feng

Nucleosides Nucleotides Nucleic Acids· November 2024

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Non-canonical regulation of the reactivation of an oncogenic herpesvirus by the OTUD4-USP7 deubiquitinases.
Shaowei Wang, Xuezhang Tian, Yaru Zhou, Jun Xie, Ming Gao, Pinghui Feng

PLoS Pathog· January 2024

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Metabolic Enzymes in Viral Infection and Host Innate Immunity.
Chao Qin, Taolin Xie, Wayne Wei Yeh, Ali Can Savas, Pinghui Feng

Viruses· December 2023

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The Apolipoprotein E neutralizing antibody inhibits SARS-CoV-2 infection by blocking cellular entry of lipoviral particles.
Qi Cui, Arjit Vijey Jeyachandran, Gustavo Garcia, Chao Qin, Yu Zhou, Lizhao Feng, Pinghui Feng

MedComm (2020)· October 2023

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The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection.
Shu Zhang, Na Xie, Yongzhen Liu, Chao Qin, Ali Can Savas, Pinghui Feng

bioRxiv· October 2023

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Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease.
Chau Ngo, William Fried, Saba Aliyari, Joshua Feng, Chao Qin, Pinghui Feng

J Med Chem· September 2023

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METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle.
Xinquan Zhang, Wen Meng, Jian Feng, Xinghong Gao, Chao Qin, Pinghui Feng

Cell Death Dis· September 2023

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Mechanistic insights into the role of herpes simplex virus 1 in Alzheimer's disease.
Shu Feng, Yongzhen Liu, Yu Zhou, Zhenfeng Shu, Zhuxi Cheng, Pinghui Feng

Front Aging Neurosci· September 2023

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STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2.
Liting Zhang, Congqing Jiang, Yunhong Zhong, Kongliang Sun, Huiru Jing, Pinghui Feng

Nat Cell Biol· August 2023

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Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses.
Xuezhang Tian, Yaru Zhou, Shaowei Wang, Ming Gao, Yanlin Xia, Pinghui Feng

mBio· April 2023

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Factor Xa cleaves SARS-CoV-2 spike protein to block viral entry and infection.
Wenjuan Dong, Jing Wang, Lei Tian, Jianying Zhang, Erik W Settles, Pinghui Feng

Nat Commun· April 2023

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STeerING PI4P for innate immune activation.
Chao Qin, Shu Feng, Pinghui Feng

Immunity· March 2023

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Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models.
Hongjia Lu, Zhewei Liu, Xiangxue Deng, Siyang Chen, Ruiting Zhou, Pinghui Feng

PLoS Pathog· March 2023

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The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness.
Kyumin Kim, Peter Calabrese, Shanshan Wang, Chao Qin, Youliang Rao, Pinghui Feng

Sci Rep· September 2022

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SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis.
Chao Qin, Youliang Rao, Hao Yuan, Ting-Yu Wang, Jun Zhao, Pinghui Feng

Proc Natl Acad Sci U S A· June 2022

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The Roles of APOBEC-mediated RNA Editing in SARS-CoV-2 Mutations, Replication and Fitness.
Kyumin Kim, Peter Calabrese, Shanshan Wang, Chao Qin, Youliang Rao, Pinghui Feng

Res Sq· April 2022

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