Publications by authors named "Pinzhu Huang"

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A novel cell-permeable LOXL2 inhibitor PAT-1251 potently suppresses biliary liver fibrosis via collagen crosslinking-dependent and -independent mechanisms.
Ping An, Guangyan Wei, Pinzhu Huang, Heansika Matta, Wenda Li

Hepatol Commun· January 2026

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Is neoadjuvant chemoradiotherapy necessary for locally advanced rectal cancer above the anterior peritoneal reflection?
Minyi He, Wuteng Cao, Qiulan He, Fujin Ye, Pinzhu Huang, Shuangling Luo, Liang Huang

Future Oncol· December 2025

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CD103-Positive Tumor-Infiltrating Lymphocytes Predict a Favorable Prognosis in Colorectal Cancer with Liver Metastasis.
Yuanhui Wu, Yumo Xie, Jinxin Lin, Ji Cui, Hui Yang, Pinzhu Huang, Anpei Huang, Meijin Huang

Ann Surg Oncol· November 2025

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Single-cell atlas of human liver and blood immune cells across fatty liver disease stages reveals distinct signatures linked to liver dysfunction and fibrogenesis.
Owen P Martin, Michael S Wallace, Christopher Oetheimer, Hailey B Patel, Michael D Butler, Pinzhu Huang

Nat Immunol· September 2025

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Assessment of compartment-specific CD103-positive cells for prognosis prediction of colorectal cancer.
Anpei Huang, Yuanhui Wu, Ji Cui, Muyan Cai, Yumo Xie, Pinzhu Huang, Meijin Huang

Cancer Immunol Immunother· June 2025

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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
Yered Pita-Juarez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C Melms, Sebastian Niezen, Pinzhu Huang

Genome Biol· March 2025

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Contrast-enhanced intraoperative ultrasound improved hepatic recurrence-free survival in initially unresectable colorectal cancer liver metastases.
HuiFang Li, Ming Shi, Xingzhang Long, Pinzhu Huang, Chuan Peng

Dig Liver Dis· February 2025

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Transposon-based oncogene integration in Abcb4(Mdr2) mice recapitulates high susceptibility to cholangiocarcinoma in primary sclerosing cholangitis.
Pinzhu Huang, Guangyan Wei, Jesse D Kirkpatrick, Yi Lin, Li Tan, Mingzhe Huang, Shuangshuang Zhao

J Hepatol· January 2025

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Clinical significance of positive resection margin for patients with rectal neuroendocrine tumors within 20 mm following initial endoscopic resection: A multi-center study.
Mengping Duan, Zhanzhen Liu, Yan Qiao, Pinzhu Huang, Hao Xie, Shuangling Luo, Liang Huang

Eur J Surg Oncol· November 2024

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Gamma-glutamyl transferase to aspartate aminotransferase ratio (GSR) predicts prognoses in patients with colorectal cancer with liver metastasis after microwave ablation.
Mingzhe Huang, Zhiliang Chen, Si Qin, Jiaming Zhou, Yan Huang, Pinzhu Huang, Jun Huang, Meijin Huang

BMC Gastroenterol· September 2024

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ASK1/ p38 axis inhibition blocks the release of mitochondrial "danger signals" from hepatocytes and suppresses progression to cirrhosis and liver cancer.
Zhenwei Peng, Guangyan Wei, Pinzhu Huang, Heansika Matta, Wen Gao, Shuangshuang Zhao

Hepatology· August 2024

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Postoperative urinary retention following transanal versus laparoscopic total mesorectal excision for rectal cancer: A randomized trial report from an experienced center.
Fujin Ye, Lei Ruan, Zhanzhen Liu, Hao Xie, Taixuan Wan, Pinzhu Huang, Liang Huang

Heliyon· July 2024

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Mitochondrial DNA copy number plays opposing roles in T-lymphocyte infiltration of colorectal cancer based on mismatch repair status: new directions for immunotherapy?
Mian Chen, Huashan Liu, Wenfeng Liang, Pinzhu Huang, Fujin Ye, Liang Huang

Br J Cancer· March 2024

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Inflammatory stress response after transanal vs laparoscopic total mesorectal excision: a cohort study based on the TaLaR trial.
Mian Chen, Fujin Ye, Pinzhu Huang, Zhenxing Liang, Huashan Liu, Shuangling Luo, Liang Huang

Int J Surg· January 2024

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Clinicopathological and molecular characteristics of colorectal adenosquamous carcinoma in an Asian population.
Fujin Ye, Mian Chen, Xiaobin Zheng, Pinzhu Huang, Chao Wang, Liang Huang

BMC Gastroenterol· January 2024

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RFX6 facilitates aerobic glycolysis-mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1.
Zhiyu Qiu, Chenwei Wang, Pinzhu Huang, Yichuan Yuan, Yunxing Shi, Zhenkun Huang

Clin Transl Med· December 2023

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Metabolic Hijacking of Hexose Metabolism to Ascorbate Synthesis Is the Unifying Biochemical Basis of Murine Liver Fibrosis.
Diren Beyoğlu, Pinzhu Huang, Disha Skelton-Badlani, Christine Zong, Yury V Popov

Cells· February 2023

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DNA methylation profile in CpG-depleted regions uncovers a high-risk subtype of early-stage colorectal cancer.
Huichuan Yu, Xiaolin Wang, Liangliang Bai, Guannan Tang, Kelly T Carter, Pinzhu Huang, Meijin Huang

J Natl Cancer Inst· January 2023

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Automated whole slide image analysis for a translational quantification of liver fibrosis.
Cindy Serdjebi, Karine Bertotti, Pinzhu Huang, Guangyan Wei, Disha Skelton-Badlani

Sci Rep· November 2022

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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
Yered Pita-Juarez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C Melms, Sebastian Niezen, Pinzhu Huang

bioRxiv· October 2022

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Development and external validation of prognostic nomograms for liver disease-free and overall survival in locally advanced rectal cancer with neoadjuvant therapy: a post cohort study based on the FOWARC trial.
Jiaming Zhou, Tuoyang Li, Yuanlv Xiao, Jinxin Lin, Xiaoqiong Chen, Mingzhe Huang, Pinzhu Huang, Meijin Huang

Ann Transl Med· June 2022

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HBV Infection Status Indicates Different Risks of Synchronous and Metachronous Liver Metastasis in Colorectal Cancer: A Retrospective Study of 3132 Patients with a 5-Year Follow-Up.
Jiaming Zhou, Xiaoyan Guo, Pinzhu Huang, Shuyun Tan, Rongwan Lin, Mingzhe Huang, Meijin Huang

Cancer Manag Res· April 2022

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MMP12 knockout prevents weight and muscle loss in tumor-bearing mice.
Lingbi Jiang, Mingming Yang, Shihui He, Zhengyang Li, Haobin Li, Pinzhu Huang, Mingzhe Huang

BMC Cancer· December 2021

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Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4 mouse model of PFIC3.
Guangyan Wei, Jingsong Cao, Pinzhu Huang, Ping An, Disha Badlani, Shuangshuang Zhao

J Hepatol· June 2021

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HBV infection may reduce the risk of metachronous liver metastasis in postoperative pathological stage 2 colorectal cancer.
Zhou Jiaming, Huang Pinzhu, Guo Xiaoyan, Tan Shuyun, Lin Rongwan, Huang Mingzhe, Huang Meijin

Int J Colorectal Dis· December 2020

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