Publications by authors named "Pitchai Balakumar"

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A map of molecular drug targets and therapeutics for the US FDA-approved drugs: The impact of expedited regulatory pathways and first-in-class drug approvals on drug innovation.
Pitchai Balakumar, N V L Sirisha Mulukuri, Gowraganahalli Jagadeesh

Pharmacol Ther· January 2026

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Differential Pre- and Post-Treatment Effects of Low-Dose Antidyslipidemic Drugs on Gentamicin-Induced Acute Nephrotoxicity in the Rat: A Histopathological and Biochemical Study.
Pitchai Balakumar, Sultan Alshahrani, Noohu Abdulla Khan, Rajavel Varatharajan, K M Sundram

J Appl Toxicol· November 2025

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Game-changing breakthroughs to redefine the landscape of the renin-angiotensin-aldosterone system in health and disease.
Pitchai Balakumar, Gowraganahalli Jagadeesh

Cell Signal· February 2025

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Impact of the local renin-angiotensin system in perivascular adipose tissue on vascular health and disease.
Pitchai Balakumar, Khalid M Orayj, Noohu Abdulla Khan, Kumaran Shanmugam, Gowraganahalli Jagadeesh

Cell Signal· December 2024

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The art and science of research methodology, biostatistics, manuscript writing, and publication ethics: An invigorating training for improving research aptitudes in southern Indian biomedical institutions.
Pitchai Balakumar, Shubhada Nagarkar, Gangaboriah Bilagumba, Ramesh Alluri, Gowraganahalli Jagadeesh

J Ayurveda Integr Med· June 2024

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Unleashing the pathological role of epithelial-to-mesenchymal transition in diabetic nephropathy: The intricate connection with multifaceted mechanism.
Pitchai Balakumar

World J Nephrol· June 2024

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India: neutralizing temptation by predatory journals.
Pitchai Balakumar, Gowraganahalli Jagadeesh

Nature· September 2023

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Mechanistic insights into the beneficial effects of curcumin on insulin resistance: Opportunities and challenges.
Pitchai Balakumar, Kumar Venkatesan, Noohu Abdulla Khan, N M Raghavendra, Vijayan Venugopal

Drug Discov Today· July 2023

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A Unifying Perspective in Blunting the Limited Oral Bioavailability of Curcumin: A Succinct Look.
Pitchai Balakumar, Taha Alqahtani, Ali Alqahtani, R Sulochana Lakshmiraj, Gurfateh Singh

Curr Drug Metab· January 2023

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Unraveling the Differentially Articulated Axes of the Century-Old Renin-Angiotensin-Aldosterone System: Potential Therapeutic Implications.
Pitchai Balakumar, Shaminder Handa, Ali Alqahtani, Taha Alqahtani, Noohu Abdulla Khan

Cardiovasc Toxicol· March 2022

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Dysregulation of the renin-angiotensin system in septic shock: Mechanistic insights and application of angiotensin II in clinical management.
Fortunato Senatore, Pitchai Balakumar, Gowraganahalli Jagadeesh

Pharmacol Res· December 2021

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The renin-angiotensin-aldosterone system: A century-old diversified system with several therapeutic avenues.
Pitchai Balakumar, Gowraganahalli Jagadeesh

Pharmacol Res· December 2021

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The physiologic and physiopathologic roles of perivascular adipose tissue and its interactions with blood vessels and the renin-angiotensin system.
Pitchai Balakumar, Ali Alqahtani, Noohu Abdulla Khan, Taha Alqahtani, Thangathirupathi A

Pharmacol Res· November 2021

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The potential modulatory role of curcumin on renal epithelial-to-mesenchymal transition in renal diseases.
Pitchai Balakumar, Ali Alqahtani, Nanjaian Mahadevan, Noohu Abdulla Khan, A Thangathirupathi

Pharmacol Res· July 2021

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Mechanistic insights into hyperuricemia-associated renal abnormalities with special emphasis on epithelial-to-mesenchymal transition: Pathologic implications and putative pharmacologic targets.
Pitchai Balakumar, Ali Alqahtani, Noohu Abdulla Khan, Nanjaian Mahadevan, Sokkalingam A Dhanaraj

Pharmacol Res· November 2020

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A Contemporary Overview of PPARα/γ Dual Agonists for the Management of Diabetic Dyslipidemia.
Pitchai Balakumar, Nanjaian Mahadevan, Ramanathan Sambathkumar

Curr Mol Pharmacol· March 2020

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A potential role of the renin-angiotensin-aldosterone system in epithelial-to-mesenchymal transition-induced renal abnormalities: Mechanisms and therapeutic implications.
Pitchai Balakumar, Ramanathan Sambathkumar, Nanjaian Mahadevan, Abdullatif Bin Muhsinah, Abdulrhman Alsayari

Pharmacol Res· August 2019

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Molecular targets of fenofibrate in the cardiovascular-renal axis: A unifying perspective of its pleiotropic benefits.
Pitchai Balakumar, Ramanathan Sambathkumar, Nanjaian Mahadevan, Abdullatif Bin Muhsinah, Abdulrhman Alsayari

Pharmacol Res· June 2019

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Renin-angiotensin-aldosterone: An inclusive, an invigorative, an interactive and an interminable system.
Pitchai Balakumar, Madhu B Anand-Srivastava, Gowraganahalli Jagadeesh

Pharmacol Res· November 2017

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Effects of pre and post-treatments with dipyridamole in gentamicin-induced acute nephrotoxicity in the rat.
Pitchai Balakumar, Wei Ern WitnessKoe, Yi Syen Gan, Soo Mei JemayPuah, Subramaniam Kuganesswari

Regul Toxicol Pharmacol· March 2017

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Prevalence and prevention of cardiovascular disease and diabetes mellitus.
Pitchai Balakumar, Khin Maung-U, Gowraganahalli Jagadeesh

Pharmacol Res· November 2016

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Chronic oral administration of low-dose combination of fenofibrate and rosuvastatin protects the rat heart against experimentally induced acute myocardial infarction.
Monika Garg, Deepa Khanna, Sanjeev Kalra, Pitchai Balakumar

Fundam Clin Pharmacol· October 2016

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Effect of edaravone in diabetes mellitus-induced nephropathy in rats.
Rajavel Varatharajan, Li Xin Lim, Kelly Tan, Chai Sze Tay, Yi Leng Teoh, Pitchai Balakumar

Korean J Physiol Pharmacol· July 2016

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Cardiovascular drugs-induced oral toxicities: A murky area to be revisited and illuminated.
Pitchai Balakumar, Muthu Kavitha, Suresh Nanditha

Pharmacol Res· December 2015

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Implications of fundamental signalling alterations in diabetes mellitus-associated cardiovascular disease .
Pitchai Balakumar

Indian J Biochem Biophys· December 2014

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