Publications by authors named "Prabitha P"

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Beyond peptides: Unveiling the design strategies, structure activity correlations and protein-ligand interactions of small molecule inhibitors against PD-1/PD-L1.
Pujan Sasmal, P Prabitha, B R Prashantha Kumar, B R Swetha, Sajeev Kumar Babasahib

Bioorg Chem· January 2025

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Novel PPAR-γ agonists as potential neuroprotective agents against Alzheimer's disease: rational design, synthesis evaluation, PPAR-γ binding assay and transactivation and expression studies.
Priya D, Umme Hani, Nazima Haider, Sirajunisa Talath, Dhivya Shanmugarajan

RSC Adv· October 2024

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Multi-conformational frame from molecular dynamics as a structure-based pharmacophore model for mapping, screening and identifying ligands against PPAR-γ: a new protocol to develop promising candidates.
P Prabitha, Dhivya Shanmugarajan, T Durai Ananda Kumar, B R Prashantha Kumar

J Biomol Struct Dyn· April 2022

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Glitazones, PPAR-γ and Neuroprotection.
Ashwini Prem Kumar, Prabitha P, B R Prashantha Kumar, Victoria Jeyarani, S P Dhanabal

Mini Rev Med Chem· August 2021

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Glitazones Activate PGC-1α Signaling via PPAR-γ: A Promising Strategy for Antiparkinsonism Therapeutics.
Prabitha P, Antony Justin, T Durai Ananda Kumar, Mithuna Chinaswamy, B R Prashantha Kumar

ACS Chem Neurosci· July 2021

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Development of Novel Rhodanine Analogs as Anticancer Agents: Design, Synthesis, Evaluation and CoMSIA Study.
Uma Krithika, Prabhakaran Prabitha, Subhankar P Mandal, Sivamani Yuvaraj, Durai Priya

Med Chem· June 2021

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Minutes of PPAR-γ agonism and neuroprotection.
B R Prashantha Kumar, Ashwini Prem Kumar, Jincy A Jose, P Prabitha, S Yuvaraj

Neurochem Int· November 2020

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Two Rationally Identified Novel Glitazones Reversed the Behavioral Dysfunctions and Exhibited Neuroprotection Through Ameliorating Brain Cytokines and Oxy-Radicals in ICV-LPS Neuroinflammatory Rat Model.
Antony Justin, Premkumar Ashwini, Jincy A Jose, Victoria Jeyarani, S P Dhanabal

Front Neurosci· September 2020

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Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets.
Dhivya Shanmugarajan, Prabitha P, B R Prashantha Kumar, B Suresh

RSC Adv· August 2020

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Rational Design, Synthesis, and In Vitro Neuroprotective Evaluation of Novel Glitazones for PGC-1α Activation via PPAR-γ: a New Therapeutic Strategy for Neurodegenerative Disorders.
Antony Justin, Subhankar Mandal, P Prabitha, S Dhivya, S Yuvaraj

Neurotox Res· March 2020

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Novel glitazones as PPARγ agonists: molecular design, synthesis, glucose uptake activity and 3D QSAR studies.
Subhankar P Mandal, Aakriti Garg, P Prabitha, Ashish D Wadhwani, Laxmi Adhikary

Chem Cent J· December 2018

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