Publications by authors named "Praful Aggarwal"

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Biomimetic fractal topography enhances podocyte maturation in vitro.
Chuan Liu, Praful Aggarwal, Karl T Wagner, Shira Landau, Teng Cui

Nat Commun· December 2025

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SARS-CoV-2 pathogenesis in an angiotensin II-induced heart-on-a-chip disease model and extracellular vesicle screening.
Qinghua Wu, Naimeh Rafatian, Karl T Wagner, Jacob Blamer, Jacob Smith, Praful Aggarwal

Proc Natl Acad Sci U S A· July 2024

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Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs-a proof-of-concept study with doxorubicin.
Li Pang, Chengzhong Cai, Praful Aggarwal, Dong Wang, Vikrant Vijay

Toxicol Sci· June 2024

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Transcriptional Variabilities in Human hiPSC-derived Cardiomyocytes: All Genes Are Not Equal and Their Robustness May Foretell Donor's Disease Susceptibility.
C Charles Gu, Andrea Matter, Amy Turner, Praful Aggarwal, Wei Yang

bioRxiv· April 2024

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Enhancing the functional maturity of hiPSC-derived cardiomyocytes to assess inotropic compounds.
Xiaoyu Zhang, Praful Aggarwal, Ulrich Broeckel, Yama A Abassi

J Pharmacol Toxicol Methods· November 2023

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Identification of CYP2D6 Haplotypes that Interfere with Commonly Used Assays for Copy Number Variation Characterization.
Amy J Turner, Praful Aggarwal, Erin C Boone, Cyrine-Eliana Haidar, Mary V Relling

J Mol Diagn· May 2021

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Donor-specific phenotypic variation in hiPSC cardiomyocyte-derived exosomes impacts endothelial cell function.
Amy Turner, Praful Aggarwal, Andrea Matter, Benjamin Olson, C Charles Gu

Am J Physiol Heart Circ Physiol· March 2021

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Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify , , and of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population.
Marguerite R Irvin, Praful Aggarwal, Steven A Claas, Lisa de las Fuentes, Anh N Do

Front Genet· February 2021

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Characterization of Reference Materials for Genetic Testing of CYP2D6 Alleles: A GeT-RM Collaborative Project.
Andrea Gaedigk, Amy Turner, Robin E Everts, Stuart A Scott, Praful Aggarwal

J Mol Diagn· November 2019

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Human IL12RB1 expression is allele-biased and produces a novel IL12 response regulator.
Allison E Reeme, Tiffany A Claeys, Praful Aggarwal, Amy J Turner, John M Routes

Genes Immun· March 2019

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Thymic regulatory T cells arise via two distinct developmental programs.
David L Owen, Shawn A Mahmud, Louisa E Sjaastad, Jason B Williams, Justin A Spanier, Praful Aggarwal

Nat Immunol· February 2019

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A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling.
Yimu Zhao, Naimeh Rafatian, Nicole T Feric, Brian J Cox, Roozbeh Aschar-Sobbi, Praful Aggarwal

Cell· February 2019

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PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.
Mei Yu, Yuhong Chen, Hu Zeng, Yongwei Zheng, Guoping Fu, Praful Aggarwal

Nat Commun· November 2017

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Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes: A GeT-RM Collaborative Project.
Victoria M Pratt, Robin E Everts, Praful Aggarwal, Brittany N Beyer, Ulrich Broeckel

J Mol Diagn· January 2016

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The introduction of RNA-DNA differences underlies interindividual variation in the human IL12RB1 mRNA repertoire.
Amy J Turner, Praful Aggarwal, Halli E Miller, Jill Waukau, John M Routes

Proc Natl Acad Sci U S A· December 2015

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Comprehensive evaluation of AmpliSeq transcriptome, a novel targeted whole transcriptome RNA sequencing methodology for global gene expression analysis.
Wenli Li, Amy Turner, Praful Aggarwal, Andrea Matter, Erin Storvick

BMC Genomics· December 2015

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RNA expression profiling of human iPSC-derived cardiomyocytes in a cardiac hypertrophy model.
Praful Aggarwal, Amy Turner, Andrea Matter, Steven J Kattman, Alexander Stoddard

PLoS One· June 2015

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IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy.
Erica G Schmitt, Dipica Haribhai, Jason B Williams, Praful Aggarwal, Shuang Jia

J Immunol· December 2012

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